Clinical and laboratory characteristics of cerebral infarction in tuberculous meningitis: A comparative study

Evaluation of cerebral infarction in tuberculous meningitis by diffusion weighted imaging

“…34 Koh et al reported cerebral infarction only in eight out of 38 (21.1%) patients. 14 The increased incidence of infarct in the present study as compared to the study of Chang et al and Koh et al may be due to the use of DWI, which is more sensitive and superior to the conventional MRI sequences in detecting small infarcts in the acute stage.…”

British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children

“…81 Infarctions as a result of ongoing vasculitis or tuberculoma are found in approximately 20% of patients at presentation. 80,82,83 More than 70% develop tuberculoma during treatment, although the majority are asymptomatic. 23 Infarctions most commonly involve the basal ganglia and the territories of the medial striate and thalamoperforating arteries.…”

Tuberculous cerebrovascular disease: A review

“…13,31,47 In an Argentinian study of 65 children with TBM, the age and sex of patients, degree of hydrocephalus and basal cistern enhancement, CSF biochemistry, cell and bacillary counts were similar in the two groups. Tuberculomas were more common in patients without infarcts, perhaps implying differences in bacterial virulence and/or host immunity.…”

“…Focal signs may be the first manifestation of TBM 27,33 or may occur after illness of short duration (less than one week). 13,16 Infarction, however, does appear to be most common in cases of longer duration, 16,31,42 although this may to some extent reflect increasing ease of infarct detection with time or the fact that severely ill patients on admission cannot be scanned. Vascular complications are more commonly seen in chronic meningitides in general than in promptly treated acute symptomatic bacterial infections.…”