“…Furthermore, in the studies carried out in India, Pakistan, and Saudi Arabia, the rate of affliction with IE was higher in men compared to women [21], [22], [24]. In our study, fever was the most frequent clinical sign in patients, which is similar to other studies [13], [18], [23], [28], [29], [30], [31]. Also, in spite of the high prevalence of vegetation among the patients, the clinical signs were not seen in all patients indicating that clinical signs can not be the key to the essential diagnosis of cardiac involvement and therefore, radiologic studies like echocardiography are necessary for its determination.…”