Clinical and Laboratory Profile of People Living with HIV/AIDS with Oral Kaposi Sarcoma

Alves, Carlos Augusto Ferreira; Assis, Midian Sousa; Maciel, Anderson da Silva; Silva, Janaína Caribé da; Ribeiro, Patrícia Miranda Leite; Lins-Kusterer, Liliane; Sarmento, Viviane Almeida

doi:10.1089/aid.2020.0311

Cited by 1 publication

(2 citation statements)

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“…The results of our evaluation are concordant with a Brazilian study on 39 patients with AIDS related KS, predominantly men, with similar mean ages (36 years vs. 32.5 years) and significant immunosuppression at the time of diagnosis of KS (LCD4 = 95.25/mm 3 vs. LCD4 = 52.6/mm 3 ) [21]. Different to the Brazilian study which referred to black race subjects, our patients were Caucasian, with a higher rate of oral cavity involvement (80% vs. 22, 8%) and a lower frequency of KS disclosing immunosuppression and HIV diagnosis (40% vs. 85.1%) [22].…”

Section: Discussionsupporting

confidence: 88%

See 1 more Smart Citation

AIDS Related Kaposi’s Sarcoma: A 20-Year Experience in a Clinic from the South-East of Romania

Arbune

Padurariu-Covit

Rebegea

et al. 2021

JCM

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Kaposi’s sarcoma (KS) was peculiarly described in the first notified cases of the acquired immunodeficiency syndrome as an opportunistic condition. However, the medical progress and the development of active antiretroviral therapy allowed the control of the HIV/AIDS epidemic, although the features of KS have changed throughout the past decades. The purpose of our study is to assess the epidemiological and clinical features of AIDS related KS in Romanian patients. A retrospective follow-up study was achieved in a single infectious diseases’ clinic from Galati—Romania, between 2001 and 2021. Referring to 290 new HIV diagnosed cases from our clinic retained in care, the prevalence of KS was 3.4%. The main characteristics of patients with KS are a median age of 33, a predominance of males, prevalent severe systemic forms of diseases, frequent association of past or concomitant tuberculosis, and context of immune reconstruction syndrome. The mortality rate was 70%. KS has occurred in patients with delayed HIV diagnoses and inadequate adherence to therapy. Early recognition of both infections, the close monitoring of latent or symptomatic tuberculosis, improving the antiretroviral adherence and raising the access to oncologic procedures in Romanian HIV patients could improve their prognosis related to KS.

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Section: Discussionsupporting

confidence: 88%

“…All patients from this study had severe immunosuppression, with LCD4 < 200/mm 3 at the time of KS diagnosis, as was expected for an opportunistic disease, but several studies during the HAART era sustain the risk of KS in HIV patients, irrespective of immunity level [20,21].…”

Section: Discussionmentioning

confidence: 60%