Clinical and microbiological features of bacteraemia with Gram-positive anaerobic cocci: a population-based retrospective study

Abstract

GPAC bacteraemia is much more common than previously reported. GPAC-bacteraemia is a condition with significant mortality mainly affecting elderly persons with comorbidities.

Clinical characteristics of bloodstream infection by Parvimonas micra: retrospective case series and literature review

“…However, since combined data of clinical characteristics about P. micra and other Parvimonas spp. were demonstrated in that study, we described the results of the literature by Badri et al in the section of discussion [9]. In 27 literature cases, P. micra bacteremia was frequently associated with spondylodiscitis (8/27, 29.6%), oropharyngeal infection (7/27, 25.9%) intraabdominal abscess (4/27, 14.8%), GIT infection (3/27, 11.1%), IE (3/ 27, 11.1%), and septic pulmonary emboli (3/27, 11.1%).…”

“…1) and were mostly detected using MALDI-TOF MS or 16S rRNA gene sequencing ( Table 2 and sTable 1). In a recent population-based study, GPAC bacteremia, identified using MALDI-TOF MS or 16S rRNA gene sequencing, was reported to be much more common than previously reported with an annual incidence of 3.4 cases per 100,000 persons per year [9], while P. micra was the most commonly isolated in the study. Thus, these new techniques might enable accurate diagnosis of P. micra bacteremia for appropriate treatment.…”

“…(96 P. micra and 4 Parvimonas spp. ), in which common focal infections were in the abdominal tract, bones and joints, the respiratory tract, and in skin/soft tissue, however, oropharyngeal infection were rarely identified [9]. Our case series and literature review indicated that it is necessary to note the GIT, oropharyngeal tract, pulmonary, vertebral spine, intra-abdominal region, and heart valves as infectious sites of P. micra bacteremia.…”

“…Recently, Badri et al demonstrated that P. micra was one of the most commonly isolated GPAC species and characteristics of Parvimonas spp. bacteremia (mostly P. micra) were discussed [9]. However, due to historical difficulties with laboratory identification, there is a paucity of published data about the clinical characteristics or mortality due to bloodstream infection by P. micra.…”

A rare case of emphysematous pyelonephritis caused by Candida parapsilosis and Finegoldia magna complicated by medical care avoidance

“…This bacteria is implicated in a range of infections including urinary tract infections, necrotizing pneumonia, Necrosis and acute inflammation extend to involve the perinephric adipose tissue (10× magnification). Blue ink was placed at the time of grossing to denote the surface of the specimen infective endocarditis, and meningitis [9]. Finegoldia magna, and other anaerobic bacteria, are well known as gas-producing pathogens.…”