Clinical and Morphological Aspects of the Application of Platelet Growth Factors in Patients With Pilonidal Cyst With Abscess

Ачкасов, Е Е; Соломка, А. Я.; Ульянов, А. А.; Безуглов, Э. Н.; Orekhova, E.V.; Жарикова, Т.М.

doi:10.24884/0042-4625-2018-177-2-52-56

Cited by 3 publications

(7 citation statements)

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“…Five studies investigated the use of PRP in open pilonidal surgery [26–28, 30, 31], three in minimally invasive pilonidal surgery [29, 33, 34], and one study reported patients in both groups [32]. A total of 621 and 309 patients were included in the open and minimally invasive groups, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 37 studies were identified and nine met the inclusion criteria (Tables 2 & 3); the included studies originated from Greece [26], Iran [27][28][29], Russia [30], Egypt [31] and Turkey [32][33][34] and were conducted between 2009 and 2021. Eight included studies were RCT's [26][27][28][29][30][31][32][33], and one was a case control study by Kurt et al [34], and all studies compared PRP treated wounds to dressings alone (Tables 2, 3). Five studies applied PRP solution to wounds on multiple days post-operatively [26,28,[30][31][32], while the other four studies all applied it within the first 36 h [27,29,33,34].…”

Section: Resultsmentioning

confidence: 99%

“…Eight included studies were RCT's [26][27][28][29][30][31][32][33], and one was a case control study by Kurt et al [34], and all studies compared PRP treated wounds to dressings alone (Tables 2, 3). Five studies applied PRP solution to wounds on multiple days post-operatively [26,28,[30][31][32], while the other four studies all applied it within the first 36 h [27,29,33,34].…”

Section: Resultsmentioning

confidence: 99%

“…All six RCTs which analyzed wound healing in open pilonidal surgery favored PRP vs dressings alone [26–28, 30–32]. An individual and combined analysis revealed significantly faster healing times for wounds treated with PRP, with pooled analysis suggesting a reduction by almost 14 days.…”

Section: Discussionmentioning

confidence: 99%

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Platelet‐Rich Plasma (PRP) for Sacrococcygeal Pilonidal Disease: An Updated Systematic Review and Meta‐Analysis

2022

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Background Pilonidal disease can be a debilitating condition which carries a significant physical and economic burden. This systematic review and updated meta‐analysis presents the evidence for the use of platelet‐rich plasma (PRP) for wound healing following open and minimally‐invasive sacrococcygeal pilonidal surgery. Methods A literature search was performed during December 2021 for studies relating to platelet‐rich plasma and pilonidal wound healing following surgery. Results Nine studies remained after applying the exclusion criteria, incorporating a total of 621 (open surgery group) and 309 (minimally‐invasive group) patients, respectively. Pooled analysis of the six open surgery group studies demonstrated a significant reduction in wound healing time (mean difference [MD] = − 13.98 days, 95% CI − 18.41 to − 9.55, p < 0.001, I2 = 98%). Three open surgery group studies compared post‐operative time off work, while three recorded mean pain duration; pooled analysis also revealed a significant reduction in both outcomes, respectively (MD = − 8.7 days, 95% CI − 9.4 to − 8.0, p < 0.001, I2 = 57%; MD = − 9.5 days, 95% CI − 15.6 to − 3.3, p = 0.002, I2 = 98%). Methodological heterogeneity among the minimally‐invasive studies precluded formal meta‐analysis; however, two studies demonstrated a modest improvement in wound healing when treated with PRP. Conclusions This systematic review and updated meta‐analysis provide further evidence supporting the use of PRP for wound healing in sacrococcygeal pilonidal disease. PRP application was demonstrated to significantly reduce healing time, postoperative pain and time off work in the open surgery group. Nevertheless, there is still considerable heterogeneity among PRP manufacture and administration techniques, and further high‐powered RCTs with consistent methodology are required to substantiate these findings.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Platelet‐Rich Plasma (PRP) for Sacrococcygeal Pilonidal Disease: An Updated Systematic Review and Meta‐Analysis

2022

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“…Однак, епітелізація вторинних норицевих ходів відбувається значно повільніше ніж первинних, оскільки процес розповсюджується з герміногенної зони дна розірваного волосяного фолікула, який має значно більший мітотичний потенціал у порівнянні зі звичайним епітелієм шкіри [13]. Окрім цього, в даному процесі мають значення вроджені чинники будови крижово-куприкової ділянки, такі як: виразність волосяного покрову, індивідуальна морфологічна особливість волосяних стрижнів, наявність мезенхімальної тканини у загальній структурі «причинної» зони можливого ураження, а також функціональна активність потових та сальних залоз, яка залежить від індивідуальної, зазвичай вродженої, гормональної складової, доказом чого є факт переважання ПХ у дітей та осіб молодого віку [1,5].…”

Section: клінічний випадокunclassified

Pilonidal disease in children: some links of etiopathogenesis of the disease (clinical observation)

Shavliuk¹,

Konoplitskiy²

2020

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Вінницький національний медичний університет імені М.І. Пирогова, Україна WĂĞĚŝĂƚƌŝĐ ^ƵƌŐĞƌǇ͘hŬƌĂŝŶĞ͘ϮϬϮϬ͘Ϯ;ϲϳͿ͗ Ͳ ͖ ĚŽŝ ϭϬ͘ϭϱϱϳϰͬW^͘ϮϬϮϬ͘ϲϳ͘ For citation: ^ŚĂ|ůŝƵŬ Z͕ <ŽŶŽƉůŝƚƐŬŝǇ s͘ ;ϮϬϮϬͿ͘ WŝůŽŶŝĚĂů ĚŝƐĞĂƐĞ ŝŶ ĐŚŝůĚƌĞŶ͗ ƐŽŵĞ ůŝŶŬƐ ŽĨ ĞƚŝŽƉĂƚŚŽŐĞŶĞƐŝƐ ŽĨ ƚŚĞ ĚŝƐĞĂƐĞ ;ĐůŝŶŝĐĂů ŽďƐĞƌ|ĂƚŝŽŶͿ͘ WĂĞĚŝĂƚƌŝĐ ^ƵƌŐĞƌǇ͘ hŬƌĂŝŶĞ͘ Ϯ;ϲϳͿ͗ Ͳ ͘ ĚŽŝ ϭϬ͘ϭϱϱϳϰͬW^͘ϮϬϮϬ͘ϲϳ͘

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Kinesiotaping as one of the methods of treatment of low back pain syndrome

Babelyuk¹,

Polihas²

2018

PMJUA

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About 80 % of adults feel pain in their backs at a definite moment of life. That’s also the most frequent reason why people lose their efficiency. It’s also the key factor due to which workable people miss their working days. Recently, the frequency of sickness rate of low back pain syndrome is getting higher and higher. For examples, according to the data of the organization, which aims at analyzing pathological conditions and diseases, which cause death or looseness of efficiency, in 1990 in the USA, low back pain syndrome took the sixth place, but in 2010 back pain went up to the third place, giving the way only to ischemic heart disease (IHD) and chronic obstructive pulmonary disease (COPD). So, we can imagine how common, widespread and serious for modern world became the problem of back pain. That’s why, only now doctors throughout the world are starting to form their separate individual researches into one qualitative and useful list of recommendations to begin an effective fight with this serious medical and social problem. Kinesiotaping (“kinesio” – movement + “tape”) – is an effective treatment and rehabilitation method of muscle and joints injuries with the help of special elastic tapes – namely kinesio tapes. The article focuses on the method of kinesiotaping and the ways of its usage for treating low back pain syndrome. The research also highlights the history of appearance and development of kinesiotaping as a method of treatment, physiological features of kinesio tape and ways of its usage in everyday medical practice. Besides analyzing recent researches in this field we provide descriptions of three clinical cases from our own medical practice which proves the effectiveness of kinesiotaping in the complex treatment of low back pain syndrome. After deep analysis of the patients’ condition we can state that due to kinesiotaping which is used together with other physiotherapeutic methods and exercises, they recover quickly than those who do not undergo kinesiotaping procedures.

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Clinical and Morphological Aspects of the Application of Platelet Growth Factors in Patients With Pilonidal Cyst With Abscess

Cited by 3 publications

References 2 publications

Platelet‐Rich Plasma (PRP) for Sacrococcygeal Pilonidal Disease: An Updated Systematic Review and Meta‐Analysis

Platelet‐Rich Plasma (PRP) for Sacrococcygeal Pilonidal Disease: An Updated Systematic Review and Meta‐Analysis

Pilonidal disease in children: some links of etiopathogenesis of the disease (clinical observation)

Kinesiotaping as one of the methods of treatment of low back pain syndrome

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