2023
DOI: 10.37349/etat.2023.00163
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Clinical and mutational profile of AT-rich interaction domain 1A-mutated cancers

Rosa Falcone,
Marco Filetti,
Pasquale Lombardi
et al.

Abstract: Aim: AT-rich interaction domain 1A (ARID1A) encodes a key component of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex that participates in gene expression. ARID1A alterations are quite common among cancer patients, although their role remains debated. The aim of this article was to study ARID1A-mutated cancer patients. Methods: Molecular and clinical data of cancer patients evaluated at Phase 1 Unit of Fondazione Policlinico Universitario A. Gemelli IRCCS were collected. Molecular an… Show more

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