Clinical and Operative Factors Related to Successful Revision Arthrodesis in the Foot and Ankle

Abstract

Level IV, case series.

A Retrospective Clinical Comparison of Two Allogeneic Bone Matrices Containing Viable Osteogenic Cells in Patients Undergoing Foot and/or Ankle Arthrodesis

“…The importance of a sufficient volume of graft material in achieving foot or ankle fusion was previously described [34,35]. That study demonstrated a decrease in fusion rate with increased volume of graft material.…”

“…Since both T EV or T EL groups utilized the same window, this does not affect the comparative conclusions. In addition, this 4-month window is relatively narrow compared to recently published retrospective studies that utilized windows ranging from 16-48 months [34,36,37]. Lastly, retrospective studies have the potential for selection bias.…”

A Multicenter, Retrospective, Case Series of Patients With Charcot Neuroarthropathy Deformities Undergoing Arthrodesis Utilizing Recombinant Human Platelet-derived Growth Factor With Beta-Tricalcium Phosphate

“…The increased utility of operative intervention for complex limb salvage in conditions such as Charcot neuroarthropathy has resulted in an awareness of the intricacies of bone consolidation, despite the availability and use of improved fixation constructs. The foot and ankle literature report nonunion rates in arthrodesis as high as 41% in high-risk populations, including those with Charcot neuroarthropathy (1,2). As such, construct augmentation with grafting material is an area of research that warrants attention.…”

Bone Regeneration in Critical-Sized Bone Defects Treated with Additively Manufactured Porous Metallic Biomaterials: The Effects of Inelastic Mechanical Properties

“…However, non-union is observed in 4.9% of the cases treated for bone fracture [1]. In 23% of ankle arthrodesis cases, for example, non-unions persist, requiring multiple invasive procedures and causing prolonged immobilization and even permanent morbidity [2]. It is therefore important to develop bone substitutes that stimulate bone tissue regeneration and help in overcoming bony non-unions.…”