Clinical and pathologic manifestations of necrobiosis lipoidica-like skin involvement in sarcoidosis

Mendoza, Vinia; Vahid, Bobbak; Kozic, Heidic; Weibel, Sandra

doi:10.1016/j.jbspin.2006.12.007

Cited by 22 publications

(18 citation statements)

References 16 publications

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“…Focused telangiectasias have been also previously described in other granulomatous conditions, including cutaneous sarcoidosis (CS), lupus vulgaris (LV) and cutaneous leishmaniasis (CL), which may present similar clinical and at times histopathologic features [10,11]. Thereby vessels of CS, LV and CL appear shorter and with less branches and fewer in numbers than in NL; in addition, vessels in CS, LV and CL are usually associated with opaque yellow-orange globules (histopathologically corresponding to granulomas) and few milia (fig.…”

Section: Discussionmentioning

confidence: 99%

Dermoscopy of Necrobiosis Lipoidica and Granuloma Annulare

Pellicano

Caldarola²,

Filabozzi³

et al. 2013

Dermatology

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Background: Dermoscopy is traditionally used for the diagnosis of skin tumors, but it has also gained increasing interest as an adjunct in the clinical diagnosis of inflammatory skin diseases. Objective: To evaluate the dermoscopic patterns of necrobiosis lipoidica (NL) and granuloma annulare (GA) and to compare these findings with other granulomatous skin disorders. Methods: This is a retrospective analysis of patient data and clinical and dermoscopic images of histopathologically diagnosed cases of NL and GA. Results: A total of 24 cases, including 12 cases of NL and 12 cases of GA, were evaluated. In all cases of NL, dermoscopy revealed evident, sharply focused, elongated and serpentine telangiectasias, which were typically located over a whitish, structureless background. In contrast, all cases of GA were dermoscopically typified by peripheral, structureless orange-reddish borders, which were associated in 5 cases with isolated, unfocussed small vessels. Conclusion: Our study suggests that NL and GA reveal different dermoscopic patterns, which may aid the correct diagnosis. In addition, the dermoscopic patterns of NL and GA appear to differ from other forms of granulomatous diseases.

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Section: Discussionmentioning

confidence: 99%

Dermoscopy of Necrobiosis Lipoidica and Granuloma Annulare

Pellicano

Caldarola²,

Filabozzi³

et al. 2013

Dermatology

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“…A series of three patients with sarcoidosis who developed necrobiosis lipoidica-like lesions has recently been reported [89]. The granulomatous nature of necrobiosis lipoidica and sarcoidosis may explain this resemblance and makes differential diagnosis difficult.…”

Section: Necrobiosis Lipoidica-like Lesionsmentioning

confidence: 99%

Skin manifestations of sarcoidosis

Mañá

Marcoval

2012

La Presse Médicale

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“…Zu den klinischen Differenzialdiagnosen zählen das Granuloma anulare, das Erythema nodosum, die Sarkoidose und das nekrobiotische Xanthogranulom. Die klinische Mimikry vice versa wurde mehrfach publiziert und ist durch einen Sonderbegriff wie Necrobiosis-like-Sarkoidosis belegt [7,10]. Das gleichzeitige Auftreten von Granuloma anulare oder Sarkoidose mit einer Necrobiosis lipoidica kann ebenfalls eine klinische Herausforderung darstellen [2].…”

Section: Klinischer Befundunclassified

Necrobiosis lipoidica

Geissler

Laaff²,

Technau³

et al. 2011

Hautarzt

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A 69-year-old patient presented with different skin lesions all of which belonged to group of necrobiosis lipoidica. The initial histologic diagnosis was actinic granuloma O'Brien. A subsequent biopsy was interpreted as granulomatous necrobiosis lipoidica. The history of these necrobiotic variants is reviewed and exemplarily depicted with this case. Necrobiosis lipoidica is part of the spectrum of granulomatous skin disorders. Although its etiology is unclear, an association with diabetes mellitus is often discussed. Multiple therapeutic options exist, but standardized guidelines for treatment are missing.

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Clinical and pathologic manifestations of necrobiosis lipoidica-like skin involvement in sarcoidosis

Cited by 22 publications

References 16 publications

Dermoscopy of Necrobiosis Lipoidica and Granuloma Annulare

Dermoscopy of Necrobiosis Lipoidica and Granuloma Annulare

Skin manifestations of sarcoidosis

Necrobiosis lipoidica

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