Clinical and pathologic profile of breast cancer in a tertiary cancer center in Saudi Arabia.

Al-Shehri, Saleh; Abulkhair, Omalkhair; Kushi, Abdulmohsen Al; Musaad, Salma; Olayan, Ashwaq Al; Jazieh, Abdul Rahman

doi:10.1200/jco.2011.29.15_suppl.1603

Cited by 2 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This results in Saudi women in Jizan, undergoing a long referral process to reach a cancer centre, thus experiencing deterioration in their health status, or even death, before accessing cancer services (Abdelhadi , AlShehri et al . ). At present, there are no national BC education and screening programmes in the KSA.…”

Section: Discussionmentioning

confidence: 97%

Understanding breast health awareness in an Arabic culture: qualitative study protocol

Madkhali

Santin

Noble

et al. 2016

Journal of Advanced Nursing

View full text Add to dashboard Cite

Abstract:Aims. To explore breast health awareness and the early diagnosis and detection methods of breast cancer from the perspective of women and primary health care providers in the Jizan region of the Kingdom of Saudi Arabia.Background. While there is a high incidence of advanced breast cancer in young women in the Kingdom of Saudi Arabia, there is no standardised information regarding breast self-examination, nor is there a national screening programme involving clinical breast examination and mammography available.Design. A qualitative exploratory study.Methods. Data collection will consist of 36 face-to-face semi-structured interviews:12 with general practitioners; 12 with nurses at primary health care centres; and with 12 women who attend the health centres. This study will be carried out in eight states across the Jizan region (four rural and four urban) to reflect the cultural diversity of Jizan. The data will be analysed using thematic content analysis. Research Ethics Committee's approval was obtained in June 2015.Discussion. While we understand the enablers and barriers to breast health awareness outside of Saudi culture, within the Kingdom of Saudi Arabia, particularly in rural populations such as Jizan, there is a paucity of research. This study will add positively to the international knowledge base of this topic. The findings will provide evidence and inform policy about women and health care providers' experiences in Jizan in a society such topics are taboo.

show abstract

Section: Discussionmentioning

confidence: 97%

Understanding breast health awareness in an Arabic culture: qualitative study protocol

Madkhali

Santin

Noble

et al. 2016

Journal of Advanced Nursing

View full text Add to dashboard Cite

show abstract

“…Compared to the Western population, BCs have diverse clinical, pathological and molecular features including early onset, higher tumor grade, higher human epidermal growth factor receptor (HER)2 amplification rate, more aggressive subtypes and a lower rate of luminal subtype, in the GCC population ( 7 – 9 ). Evidence suggests that approximately 46.2% to 54% of BC patients are diagnosed at advanced disease stage ( 7 , 8 , 10 – 12 ), 23.3% to 28% are diagnosed with localized tumors while ≤2% with in-situ carcinoma ( 8 , 10 ). In the GCC region, the vast majority of BC cases (82.1% to 93%) have invasive ductal carcinoma (IDC) ( 7 , 8 ), and 19.2% to 29.5% have HER2 overexpression ( 7 , 8 , 12 ), while 14.3% to 26.9% have triple-negative BC (TNBC) ( 7 , 8 ).…”

Section: Introductionmentioning

confidence: 99%

“…Evidence suggests that approximately 46.2% to 54% of BC patients are diagnosed at advanced disease stage ( 7 , 8 , 10 – 12 ), 23.3% to 28% are diagnosed with localized tumors while ≤2% with in-situ carcinoma ( 8 , 10 ). In the GCC region, the vast majority of BC cases (82.1% to 93%) have invasive ductal carcinoma (IDC) ( 7 , 8 ), and 19.2% to 29.5% have HER2 overexpression ( 7 , 8 , 12 ), while 14.3% to 26.9% have triple-negative BC (TNBC) ( 7 , 8 ). The average age of patients at the presentation of BC is at least a decade younger in the GCC population compared to the Western population (<48 years vs 60 years) ( 7 , 13 ).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

BRCA testing and management of BRCA-mutated early-stage breast cancer: a comprehensive statement by expert group from GCC region

Al-Shamsi,

Alwbari,

Azribi

et al. 2024

Front. Oncol.

View full text Add to dashboard Cite

BReast CAncer (BRCA)1 and BRCA2 gene pathogenic variants account for most hereditary breast cancers (BC). Identification of BRCA mutations can significantly influence both prognosis and treatment outcomes. Furthermore, it enables the identification of individuals who are at heightened risk of developing BC due to inherited genetic mutations. Many developing countries rely on western guidelines for BRCA testing and BC management; however, there exist wide disparities in the prevalence of risk factors, availability of medical resources, and practice patterns. Guidelines tailored to specific regions can help mitigate healthcare variations, promote consistency in treatment, and aid healthcare providers in identifying effective therapies for improving patient outcomes. Hence, oncologists from the Gulf Cooperation Council (GCC) congregated virtually in March 2023 and reviewed existing data on the epidemiology of BC, BRCA mutations, practices and challenges associated with BRCA testing and management of BRCA mutated early-stage BC in the GCC region. They also provided insights on the real-world diagnostic and treatment practices and challenges in the GCC region in the BRCA-mutated early-stage BC domain and suggested some variations to international guidelines to aid their uptake in this region.

show abstract

Clinical and pathologic profile of breast cancer in a tertiary cancer center in Saudi Arabia.

Cited by 2 publications

References 0 publications

Understanding breast health awareness in an Arabic culture: qualitative study protocol

Understanding breast health awareness in an Arabic culture: qualitative study protocol

BRCA testing and management of BRCA-mutated early-stage breast cancer: a comprehensive statement by expert group from GCC region

Contact Info

Product

Resources

About