Clinical and perinatal outcomes in eclamptic women with posterior reversible encephalopathy syndrome

Kurdoğlu, Zehra; Çetin, Orkun; Sayın, Refah; Dirik, Deniz; Kurdoğlu, Mertihan; Kolusarı, Ali; Yıldızhan, Recep; Şahin, Hanım Güler

doi:10.1007/s00404-015-3738-6

Cited by 19 publications

(17 citation statements)

References 28 publications

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“…15 Kurdgolu Z et al and Camara-Limarroy et al reported that infants of mothers with eclampsia complicated with PRES had low 1-minute APGAR score, these findings are similar to the present study. 40,41 Comparison of other studies with the present study parameter are shown in Table 4. Limitation of the present study is that, it is a retrospective study without any control group.…”

Section: Figure 2a 2b 2c and 2d: Mri Images Of One Of The Patients mentioning

confidence: 80%

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: PRES can be associated with number of medical conditions and was observed frequently in patients with preeclampsia and eclampsia. Neuroimaging is important for the diagnosis of PRES. Study was conducted to find out the maternal and perinatal outcome in patients with eclampsia complicated by posterior reversible encephalopathy syndrome (PRES).Methods: This is a retrospective study done at St. Johns Medical College Bangalore, between October 2013 and October 2016. We reviewed case records of all the patients with eclampsia who underwent neuro imaging studies and a diagnosis of PRES was made. The maternal and perinatal outcomes in these women were studiedResults: In the past three years we had 55 cases of eclampsia who underwent neuroimaging studies for persistent neurological symptoms after 24 hours of MgSO4 treatment. Of these women 30 were diagnosed to have PRES. In the present study PRES was common in multiparous women and more in patients with antepartum eclamptic women. Mean age at diagnosis of PRES was 26±5.1 years. Common presenting symptoms were headache (93.3%) and vomiting (53.3%). The mean SBP/DBP was 180/110 mmHg. All patients who had recurrent seizures were controlled with MgSO4 alone. 53.3% of our patients had eclampsia related complications and 36.7% required ICU care. There were 3 maternal deaths (10%). Perinatal mortality was 20%.Conclusions: Neuroimaging in eclamptic patients with persistent neurological symptoms could help in early diagnosis of PRES and multidisciplinary approach in management could contribute significantly in reducing the maternal mortality and morbidity.

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Section: Figure 2a 2b 2c and 2d: Mri Images Of One Of The Patients mentioning

confidence: 80%

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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“…Há relato de concomitância entre a ocorrência de cefaleia com alterações visuais em 60% das pacientes que apresentam PRES decorrente de eclâmpsia, o que traz um importante fato: maior ocorrência dos fenômenos visuais associados à PRES no período gravídico-puerperal (KURDOGLU Z, et al, 2015). Cozzolino M, et al (2015), sintetizam que independente da presença de cefaleia ou demais sinais e sintomas que ocorrem na PRES relacionado à gestação ou puerpério, raramente a PRES se desenvolverá na ausência de crises convulsivas.…”

Section: Resultados E Discusãounclassified

Síndrome da Encefalopatia Posterior Reversível (PRES) no ciclo gravídico puerperal: revisão bibliográfica

2020

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Objetivo: Elencar as principais características fisiopatológicas, clínicas, diagnósticas e manejo terapêutico da Síndrome da Encefalopatia Posterior Reversível (PRES) em gestantes e puérperas. Métodos: Esta revisão da literatura usou a base de dados de pesquisa CAPES, com os descritores: “PRES”, “Posterior Reversible Encephalopathy Syndrome”, “Posterior Leukoencephalopathy Syndrome” e “Pregnancy”, entre os anos de 2003 a 2019, resultando em 50 artigos que preencheram os critérios de inclusão. Resultados: Verificou-se que, os mecanismos fisiopatológicos que buscam explicar a ocorrência geral dessa síndrome, ainda não são claros. Os principais sinais clínicos identificados foram convulsões associadas a cefaleia e alterações visuais. O exame padrão-ouro é a ressonância magnética, preferencialmente em T1, T2, ADC e DWI, estando a restrição de difusão relacionada a um pior prognóstico. Feito o diagnóstico, é necessário o manejo terapêutico com estabilização da paciente, controles pressórico, controle de convulsões e afastar a causa base que desencadeou o processo da PRES. Considerações finais: A PRES é uma síndrome de início agudo, sendo importante o reconhecimento das suas características clínicas e diagnósticas. Por isso quando pensar em PRES? Sugerimos um recurso mnemônico para lembrar como diagnóstico diferencial. P: Pré-eclâmpsia e eclâmpsia; R: Restrição de difusão na Ressonância Magnética; E: Edema cerebral; S: Sintomas visuais.

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“…Studies have pointed out than 9 and the level of 24h serum uric acid in women with severe PE was significantly higher than the group without RPLS ( P= 0.012). 10 …”

Section: Discussionmentioning

confidence: 99%

Expression Level of IL-17 in Peripheral Blood of Patients with Late Pregnancy and Diagnosis of Maternal-Fetal Tolerance Based on Brain MRI Image Segmentation Algorithm

Yu¹,

Zhou

Tan³

et al. 2021

Pak J Med Sci

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Objectives: To study the expression of IL-17 in peripheral blood and its effect on maternal-fetal tolerance in patients with eclampsia in late pregnancy using MRI image segmentation algorithm. Methods: Thirty-nine patients with severe preeclampsia and eclampsia with brain symptoms were examined by cranial MRI. Pregnant women with 32 weeks of pregnancy were selected to detect the percentage of Th17 and Treg cells in CD4 + T lymphocytes and the expression of cytokines IL-17 and IL-10 in peripheral blood. Results: MRI examination was normal in 26 cases, 9 cases showed reversible posterior encephalopathy syndrome, three cases were cerebral hemorrhage, and one case was intracranial cavernous sinus thrombosis. two. Compared with the mild preeclampsia group, the relative number of Thl7 cells increased and that of Treg cells decreased in the severe preeclampsia group (P>0.05). Conclusion: The major types of cerebrovascular diseases (CVD) in severe preeclampsia and eclampsia were reversible posterior encephalopathy syndrome and cerebral hemorrhage. It was speculated that the damage to the blood-brain barrier may play an important role in the pathogenesis. The balance of the number of Th17 cells/the number of Treg cells was more inclined to the Th17 cell-mediated pro-inflammatory state, Treg cell-mediated immune tolerance decreases, and it becomes more obvious with the worsening of the disease. doi: https://doi.org/10.12669/pjms.37.6-WIT.4828 How to cite this:Yu Z, Zhou S, Tan Z, Lu G. Expression Level of IL-17 in Peripheral Blood of Patients with Late Pregnancy and Diagnosis of Maternal-Fetal Tolerance Based on Brain MRI Image Segmentation Algorithm. Pak J Med Sci. 2021;37(6):1553-1557. doi: https://doi.org/10.12669/pjms.37.6-WIT.4828 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Clinical and perinatal outcomes in eclamptic women with posterior reversible encephalopathy syndrome

Abstract: This study indicates that PRES manifests predominantly with headache and visual impairment together. Adverse neonatal outcomes are also common in these patients.

Cited by 19 publications

References 28 publications

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Síndrome da Encefalopatia Posterior Reversível (PRES) no ciclo gravídico puerperal: revisão bibliográfica

Expression Level of IL-17 in Peripheral Blood of Patients with Late Pregnancy and Diagnosis of Maternal-Fetal Tolerance Based on Brain MRI Image Segmentation Algorithm

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