“…Substance use can develop as method of attempting to cope with psychological distress (the self-medication hypothesis) (Khantzian, 1997); there is evidence supporting a longitudinal association between SI and substance use in young people (Marschall-Lévesque et al, 2017;Rioux et al, 2021). The disinhibitory effects of alcohol and heightened tolerance for pain may also play important facilitatory roles in suicidal behaviour (Bridge et al, 2006;Deykin and Buka, 1994;Esposito and Clum, 2002;Grimmond et al, 2019; Australian & New Zealand Journal of Psychiatry, 56( 8) Reifman and Windle, 1995) and intoxication (with alcohol or other substances) is found in a high proportion of suicide attempts and suicide deaths among young people (Bohaterewicz et al, 2020;Lahti et al, 2014;Méan et al, 2005;Pelkonen and Marttunen, 2003). Given the relatively high comorbidity of depression and substance use in young people, non-judgmental screening and assessment for substance use could be a useful component of depression treatment approaches (Brown et al, 2016;Winters and Kaminer, 2008).…”