Clinical and radiographic evaluation of periodontal intrabony defects by open flap surgery alone or in combination with Biocollagen ^® membrane: A randomized clinical trial

Abstract

Background:Guided tissue regeneration (GTR) is often incorporated in regenerative periodontal surgical procedures. However, the actual benefits of adding GTR to such a procedure remain undocumented. The purpose of this randomized controlled trial was to investigate the contribution of GTR to the outcomes of open flap debridement (OFD) in the treatment of intrabony defects.Materials and Methods:A total of 16 patients of both sexes satisfying the criteria of chronic periodontitis and each of whom displayed one intrabony defect were randomly assigned to two groups, i.e. either treated with open flap surgery and GTR (group 1) or with open flap surgery alone (group 2), in this parallel-arm study. The soft tissue and hard tissue measurements, including probing pocket depth (PD), clinical attachment level (CAL), and bone mineral density were recorded at baseline and 3,6 and 12 months after surgery. The differences with a P < 0.05 were considered significant.Results:Results showed that the membrane group showed significant difference when compared with open flap surgery alone, in relation to the degree of periodontal pocket, clinical attachment loss, and bone density.Conclusion:The findings of this study suggest that biocollagen membrane could be considered as an option in the treatment of intrabony defects. Biocollagen membrane alone gives favorable clinical results in the treatment of intrabony defects. Open flap debridement resulted in acceptable clinical results in the treatment of intrabony defects.

Effect of Osteontm Ii Collagen in The Treatment of Chronic Periodontitis Patients: A Clinical And Radiographical Study

“…Our study used open flap debridement alone as the treatment for defect in the control group, which is consistent with previous research showing that open root debridement left the affected region free from calculus depositions than the closed debridement approach (Elkhatat et al, 2015). Additionally, Schmitt et al, (1989) noted in their study that it was difficult to use a typical periodontal equipment to reach the base of the vertical defect.…”

The effect of titanium-platelet rich fibrin on periodontal intrabony defects: A randomized controlled split-mouth clinical study

“…In the past, many research studies have used bone grafts and membranes together [ 38 ] and PRF alone or in combination with grafts [ 39 ] in the regenerative periodontal treatment. Previous reports have been controversial regarding the use of platelet concentrates alone or in combination with bone graft substitutes.…”

Regeneration of Intrabony Defects Using a Novel Magnesium Membrane

“…However, some authors have reported that the use of a collagen membrane in combination with xenograft provides no additional benefit when applied to large vertical defects [12,39]. Nevertheless, the use of a resorbable membrane provides a better clinical outcome in comparison to open-flap debridement performed alone [12,40,41]. The lack of clinical benefit of using a collagen membrane when used in combination with a bone graft for the vertical augmentation of IBDs could be associated with its low mechanical strength and inability to resist the pressure exerted on the augmentation material from the overlying soft tissue [13].…”