Clinical and Radiographic Evaluation of the Effectiveness of Formocresol, Mineral Trioxide Aggregate, Portland Cement, and Enamel Matrix Derivative in Primary Teeth Pulpotomies: A Two Year Follow-Up

Yıldırım, Ceren; Başak, Feridun; Akgün, Özlem Martı; Polat, Günseli Güven; Altun, Ceyhan

doi:10.17796/1053-4628-40.1.14

Cited by 42 publications

(40 citation statements)

References 19 publications

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“…Furcation radioluceny and abnormal root resorption were observed as common radiographic findings in formocresol group in the current study. These findings were in accordance with Ibricevic & Qumasha [31] ; Holan et al [32] ; Ruby et al [33] ; Havale et al [34] ; Yildirim et al [35] , they contributing the radiographic changes after Formocresol pulpotomy to different factors such as the possibility of penetration of formaldehyde through the pulpal floor with subsequent damage to the interradicular area.…”

Section: Discussionsupporting

confidence: 88%

Clinical, Radiographical and Histopathological Evaluation of Biodentine Versus Formocresol In Primary Teeth Pulpotomy

Khatab

Deraz

2019

Egyptian Dental Journal

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Aim:The present study was conducted to compare effects of biodentine and formocresol as pulp-dressing agents clinically, radiographically and histopatholically in primary teeth. Materials and Methods:Thirty healthy children aged from four to eight years, they were selected from patients attending outpatient clinic of Pediatric Dentistry Department. Each child had at least bilateral deep carious lower primary molar indicated for pulpotomy. Pulpotomy was done in both groups; where group I treated by biodentine while formocresol used in group II. The study cases were recalled after three, six, nine and twelve months for clinical and radiographic evaluation. For histopathological study sixteen lower primary first molars planned for serial extraction were selected, biodentine and formocresol pulpotomies were done, extraction of the treated teeth from each group was done after one and three-month intervals.Results: the overall clinical success rate of biodentine group was 90%, while formocresol group was 80%. The two groups were clinically successful with no statistically significant difference between them (P= 0.278). The radiographic success rate of biodentine group was 86.6%, while for formocresol group was 73.3%. There was no statistically significant difference between the two groups (P = 0.197). Biodentine showed significantly better histopathological results compared to formacresol after three-month interval. Biodentine favored the formation of partial dentine bridge with normal pulpal architecture. The pulp tissue in formocresol group showed necrosis with no evidence of dentine bridge formation Conclusion: the biodentine showed higher clinical, radiographic and histopathologic success rate compared to formocresol as a pulpotomy agent in primary molars. It can be considered as a biomaterial for vital pulp therapy of deep caries in primary teeth.

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Section: Discussionsupporting

confidence: 88%

Clinical, Radiographical and Histopathological Evaluation of Biodentine Versus Formocresol In Primary Teeth Pulpotomy

Khatab

Deraz

2019

Egyptian Dental Journal

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“…No significant differences in clinical signs and symptoms (presence of pain, sensitivity on percussion and palpation, discoloration, swelling, sinus tract, mobility, lymphadenopathy related to the site of treatment) and radiographic observations (periodontal widening, periapical and furcation radiolucency, external and internal resorption, canal obliteration) were found between enamel matrix derivatives with ProRoot MTA (Yildirim et al . ) as well as diode laser with MTA after pulpotomy in primary molars (Uloopi et al . ).…”

Section: Vital Pulp Therapiesmentioning

confidence: 99%

Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview – part I: vital pulp therapy

2017

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Mineral trioxide aggregate (MTA) is a bioactive endodontic cement (BEC) mainly comprised of calcium and silicate elements. The cement was introduced by Torabinejad in the 1990s and has been approved by the Food and Drug Administration to be used in the United States in 1997. A number of new BECs have also been introduced to the market, including BioAggregate, Biodentine, BioRoot RCS, calcium-enriched mixture cement, Endo-CPM, Endocem, EndoSequence, EndoBinder, EndoSeal MTA, iRoot, MicroMega MTA, MTA Bio, MTA Fillapex, MTA Plus, NeoMTA Plus, OrthoMTA, Quick-Set, RetroMTA, Tech Biosealer and TheraCal LC. It has been claimed that these materials have properties similar to those of MTA without its drawbacks. In this article, the chemical composition and the application of MTA and other BECs for vital pulp therapy (VPT), including indirect pulp cap, direct pulp cap, partial pulpotomy, pulpotomy and partial pulpectomy, have been reviewed and compared. Based on selected keywords, all papers regarding chemical composition and VPT applications of BECs had been reviewed. Most of the materials had calcium and silicate in their composition. Instead of referring to the cements based on their chemical compositions, we suggest the term 'bioactive endodontic cements (BECs)', which seems more appropriate for these materials because, in spite of differences in their chemical compositions, bioactivity is a common property for all of them. Numerous articles were found regarding use of BECs as VPT agents for indirect and direct pulp capping, partial pulpotomy and cervical pulpotomy. Most of these investigations used MTA for VPT. In most studies, newly introduced materials have been compared to MTA. Some of the BECs have shown promising results; however, the number of their studies compared to investigations on MTA is limited. Most studies had several methodological shortcomings. Future investigations with rigorous methods and materials are needed.

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“…Seven studies [75,79,81,82,84,89,91] reported better clinical outcomes of FC than FS. On the other hand, the comparison between FC and MTA [55,66,67,70,72,[76][77][78]85,86,88,90], yielded a better performance of the latter after 12, 24, 30 and 42 months of evaluation. Accordingly, El Meligy et al [87] observed slightly favorable clinical and radiographical outcomes of primary teeth underwent pulpotomy performed with BD than FC, although no statistically significant.…”

Section: Discussionmentioning

confidence: 99%

“…The same trend was maintained even after 30 [77] and 42 [78] months of evaluation, respectively. In two additional studies [66,88], it was reported that FC showed slightly worse results than MTA at a 24-month evaluation; however, it performed better than other materials assessed during pulpotomy of primary teeth, such as Pulpotec and Emdogain [88], as well as Portland cement and enamel matrix protein [66]. On the other hand, Jamali et al [65] reported a superiority of MTA in respect to FC after 24 months of evaluation, even though both groups yielded worse results when compared to 3Mixtatin (a combination of simvastatin and 3Mix antibiotic) (78.9% for FC, 90.5% for 3Mixtatin and 88.1% for MTA).…”

Section: Mtamentioning

confidence: 96%

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Bossù

Iaculli

Giorgio

et al. 2020

JCM

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Background: Pulpotomy of primary teeth provides favorable clinical results over time; however, to date, there is still not a consensus on an ideal pulp dressing material. Therefore, the aim of the present systematic review was to compare pulpotomy agents to establish a preferred material to use. Methods: After raising a PICO question, the PRISMA guideline was adopted to carry out an electronic search through the MEDLINE database to identify comparative studies on several pulp dressing agents, published up to October 2019. Results: The search resulted in 4274 records; after exclusion, a total of 41 papers were included in the present review. Mineral trioxide aggregate (MTA), Biodentine and ferric sulphate yielded good clinical results over time and might be safely used in the pulpotomies of primary molars. Among agents, MTA seemed to be the material of choice. On the contrary, calcium hydroxide showed the worst clinical performance. Although clinically successful, formocreosol should be replaced by other materials, due to its potential cytotoxicity and carcinogenicity. Conclusion: MTA seemed to be the gold standard material in the pulpotomy of primary teeth. Promising results were also provided by calcium silicate-based cements. Further randomized clinical trials (RCTs) with adequate sample sizes and long follow-ups are encouraged to support these outcomes. deciduous or young permanent teeth with immature roots affected by caries and without evidence of radicular pathology [7,8]. Nowadays, treatment options of VPT are represented by indirect pulp treatment (namely indirect pulp capping), direct pulp capping and pulpotomy [7]. Although clinically successful in primary molars, direct capping is mainly recommended in the VPT of permanent young teeth [9,10] and indirect capping seems to possess a relative effectiveness when compared to pulpotomy procedures [11]. The latter provides favorable clinical survival rates over time and allows the vitality of primary teeth until their natural exfoliation, avoiding pulpectomy procedures [2]. Pulpotomy consists of elimination of the bacterial infection by the removal of the pulp in the pulp chamber; then, the decontaminated tooth is filled with a medicament [11]. The most frequently used agents are mineral trioxide aggregate (MTA), Biodentine (BD), formocresol (FC), ferric sulphate (FS) and calcium hydroxide (CH). When compared, FC, FS and MTA seemed to provide significantly better clinical and radiographic results as pulpotomy agents than CH after two years of follow-up; moreover, MTA showed the best performance in respect to FC and FS over time [12]. Accordingly, Stringhini et al. [13] reported that MTA yielded superior clinical and radiographical results in comparison to FC. On the other hand, electrosurgery and FS showed similar success to FC, whereas CH did not show positive evidence as medicament in pulpotomies of primary teeth [13]. In the same way, Asgary et al. [14] further stressed that MTA demonstrated better long-term outcomes in pulpotomy of primary molars when com...

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Clinical and Radiographic Evaluation of the Effectiveness of Formocresol, Mineral Trioxide Aggregate, Portland Cement, and Enamel Matrix Derivative in Primary Teeth Pulpotomies: A Two Year Follow-Up

Abstract: Although there were no statistically significant differences in clinical and radiographic success rates among the 4 groups, MTA appears to be superior to formocresol, Portland cement, and enamel matrix derivative as a pulpotomy agent in primary teeth.

Cited by 42 publications

References 19 publications

Clinical, Radiographical and Histopathological Evaluation of Biodentine Versus Formocresol In Primary Teeth Pulpotomy

Clinical, Radiographical and Histopathological Evaluation of Biodentine Versus Formocresol In Primary Teeth Pulpotomy

Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview – part I: vital pulp therapy

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

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