Clinical and radiographic evaluation of pulpectomy in primary teeth: a 18-months clinical randomized controlled trial

Abstract

BackgroundTo avoid untoward changes when primary teeth are replaced by permanent teeth, resorption of the material used in primary teeth root canal filling should occur at the same rate as root resorption. The Aim of this study was to compare the success rates of a mixed primary root canal filling (MPRCF, ingredients: zinc oxide–eugenol [ZOE], iodoform, calcium hydroxide) to those of ZOE and Vitapex in pulpectomised primary molars.MethodsOne hundred and sixty primary molars from 155 children (average age 5.88 ± 1.27 years) underwent two-visit pulpectomy using one of the three materials. The clinical and radiographic findings at 6, 12 and 18 months were assessed.ResultsAt 6 and 12 months, the MPRCF and ZOE success rates were 100%. The Vitapex group showed clinical success rate and radiographic success rate of 100 and 94.5% at 6 months, and 80.4 and 60.7% at 12 months. The 18-month clinical success rates of the MPRCF, ZOE and Vitapex were 96.2, 92.2 and 71.4% and radiographic success rates were 92.5, 88.2 and 53.6%, respectively. There was a statistically significant difference in the success rates between MPRCF and Vitapex and no significant differences between MPRCF and ZOE. More MPRCF were resorbed at same rate with roots than ZOE and Vitapex. Early resorption of root filling resulted in more failure.ConclusionsThe mixture of ZOE, iodoform and calcium hydroxide can be considered an effective root canal filling material in pulp involved primary teeth and had no adverse effect on tooth replacement.Trial registration ChiCTR-TRC-14004938. Registered 13 July 2014.

A comparison of calcium hydroxide/iodoform paste and zinc oxide eugenol as root filling materials for pulpectomy in primary teeth: A systematic review and meta‐analysis

“…The 15 studies included in the presented SR (Table ) included 1,669 primary teeth (337 anterior teeth and 1,332 molars), of children aged between 3 and 13 years, pulpectomized and had follow‐up period ranged from 2 (Ozalp, Saroglu, & Sonmez, ; Xiao‐Fang & Xue‐Bin, ) to 30 months (Pramila et al, ) The only study with a follow‐up period shorter than 2 months reported follow‐up data after 1 week (Ping‐ping, ). From these studies, 11 included primary molars only (Al‐Ostwani et al, ; Chen et al, ; Gupta & Das, ; Ming‐zhi et al, ; Ozalp et al, ; Ping‐ping, ; Pramila et al, ; Ramar & Mungara, ; Subramaniam & Gilhotra, ; Trairatvorakul & Chunlasikaiwan, ; Xiao‐Fang & Xue‐Bin, ), and four studies included both primary incisors and molars (Chen & Liu, ; Mortazavi & Mesbahi, ; Wei‐jian, ; Yu‐xiang et al, ).…”

“…Only the aforementioned Ca(OH) 2 /iodoform products, Metapex and Vitapex, were used in these studies; Metapex was used in four studies (Al‐Ostwani et al, ; Gupta & Das, ; Ramar & Mungara, ; Subramaniam & Gilhotra, ), whereas Vitapex was used in 10 studies (Chen et al, ; Chen & Liu, ; Ming‐zhi et al, ; Mortazavi & Mesbahi, ; Ozalp et al, ; Pramila et al, ; Trairatvorakul & Chunlasikaiwan, ; Wei‐jian, ; Xiao‐Fang & Xue‐Bin, ; Yu‐xiang et al, ), and one study mentioned using Ca(OH) 2 /iodoform without mentioning its manufacturer (Ping‐ping, ).…”

“…Variations were present in the number of treatment visits, the latency to follow‐up examination, the type of irrigation solution used, and the final restorative material used (Table ). Ca(OH) 2 /iodoform paste was compared with ZOE in 8 studies (Chen & Liu, ; Gupta & Das, ; Ming‐zhi et al, ; Mortazavi & Mesbahi, ; Ozalp et al, ; Trairatvorakul & Chunlasikaiwan, ; Wei‐jian, ; Xiao‐Fang & Xue‐Bin, ), ZOE/ iodoform in two studies (Ping‐ping, ; Yu‐xiang et al, ), ZOE and ZOE/iodoform combined with Ca(OH) 2 in three studies (Al‐Ostwani et al, ; Chen et al, ; Subramaniam & Gilhotra, ), ZOE and ZOE/iodoform in one study (Pramila et al, ), and ZOE/iodoform and ZOE/iodoform combined with Ca(OH) 2 in one study (Ramar & Mungara, ).…”

“…Our initial search was conducted in April 2016. A subsequent search that was performed in January 2018 revealed one additional study (Chen, Liu, & Zhong, ) for inclusion.…”

Allium sativum extract as an irrigant in pulpectomy of primary molars: A 12‐month short‐term evaluation

“…Although the radiographic success rate was 85% after 12 months of the follow‐up period, which was comparable with this study results (Trairatvorakul & Chunlasikaiwan, ). Chen et al () reported 100% clinical and radiographic success rates at 6 and 12 months success rates of ZOE pulpectomy (Chen, Liu, & Zhong, ). These differences in findings might be related to the use of two visits pulpectomy method.…”