Clinical and radiographic evaluation of the efficacy of sodium hypochlorite as a haemostatic agent compared with physiologic saline on the success of calcium hydroxide pulpotomies in primary molars: an in vivo study

Hemavathi,; Nagarathna, J; Srinath, Sahana; Hiremath, Mallayya C

doi:10.1007/s40368-018-0377-1

Cited by 3 publications

(4 citation statements)

References 18 publications

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“…Full texts of 102 studies were retrieved for final eligibility evaluation because 8 eligible studies were identified from previous meta-analyses. Finally, 43 studies [ 2 , 3 , 10 , 36 – 75 ] were included in the network meta-analysis after excluding 66 studies due to ineligible follow-up period ( n = 3), ineligible subject ( n = 1), ineligible interventions ( n = 1) [ 76 ], ineligible topic ( n = 49), not accessible ( n = 7), and no outcome ( n = 6). The process of study retrieval and selection is displayed in Fig.…”

Section: Resultsmentioning

confidence: 99%

Comparative efficacy of medicaments or techniques for pulpotomy of primary molars: a network meta-analysis

2022

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Objectives We performed this network meta-analysis to determine the comparative efficacy of formocresol (FC), ferric sulfate (FS), sodium hypochlorite (NaOCl), calcium hydroxide (CH), mineral trioxide aggregate (MTA), biodentine, and laser for pulpotomy of molar teeth. Materials and methods An updated search was conducted in PubMed, Embase, and the Cochrane Library to identify relevant randomized controlled trials (RCTs) published before October 30, 2022, after screening previous meta-analyses. The Cochrane risk of bias assessment tool was used to appraise the methodological quality of included studies. Clinical and radiographic success rates were assessed as outcomes. Random network meta-analysis was performed by using STATA software (version 14.0) with “network” command. Results A total of 43 RCTs were included. Network meta-analysis indicated that CH was inferior to other medicaments and techniques in all outcomes, and MTA and biodentine was better than FC, FS, and NaOCl in terms of clinical and radiographic success rates. Results of ranking probabilities suggested that MTA ranked first in all outcomes except for clinical success at both 6 months. Conclusions Our results suggested that MTA was associated with significant improvement in both clinical and radiographic success than other pulpotomy medicaments and techniques, with the highest probability of being the optimal option. Clinical relevance The current network meta-analysis determined the comparative efficacy and safety of 7 common pulpotomy medicaments in molar pulpotomy, including FC, FS, NaOCl, CH, MTA, biodentine, and laser, and the pooled results revealed comparable efficacy in clinical and radiographic success rates at 6 and 12 months between FC, FS, and NaOCl in primary molars pulpotomies. However, MTA, biodentine and laser may have more advantages than other pulpotomy medicaments for clinical and radiographic success. Therefore, in clinical practice, practitioners should select MTA, biodentine, or laser as pulpotomy medicaments in molar pulpotomy.

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Section: Resultsmentioning

confidence: 99%

Comparative efficacy of medicaments or techniques for pulpotomy of primary molars: a network meta-analysis

2022

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“…Therefore, a pulpotomy is a suitable therapeutic procedure for managing infection of the coronal pulp tissue in teeth because of its exceptionally high positive outcomes. 21 The preservation of healthy radicular pulp tissue offers nutritional support for teeth, contributes to the formation of a dentin bridge, and preserves the primary teeth's integrity. 22 The optimal pulpotomy material must inhibit bacterial formation, be biocompatible with the pulp and its surrounding tissues, support healing and viability of the radicular pulp, and not interfere with the physiological root resorption process.…”

Section: Discussionmentioning

confidence: 99%

“…However, only a few clinical trials have evaluated the efficacy of NaOCl as a medicament in pulpotomy procedures of primary teeth, and data support its application in the biochemical amputation of the dental pulp, which leads to the formation of a dentin-pulp interface free of coagulum debris before the base material placement. 14,15 According to preliminary clinical investigations, NaOCl could be a viable option for pulpotomy medication for primary teeth. [16][17][18] However, few studies have compared the success of FS, which has been used frequently in primary tooth pulpotomy for many years, with sodium hypochlorite in clinical applications.…”

Section: Introductionmentioning

confidence: 99%

Retrospective analysis of ferric sulfate and sodium hypochlorite pulpotomy procedures in primary molars

Akman,

Surme

2023

J Dent Res Dent Clin Dent Prospects

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Background. Pulpotomy is a vital pulp treatment procedure frequently used in primary molars to preserve pulp vitality and function until tooth exfoliation. There is currently no pulp medicament with all the features of the ideal pulpotomy material. The present study compared the radiographic success of sodium hypochlorite with ferric sulfate (FS) when used for pulpotomy in primary molars. Methods. A retrospective analysis was performed to evaluate the success rates of primary molars pulpotomized using sodium hypochlorite or FS according to radiographic findings. Healthy 4‒10-year-old children who had pulpotomy procedures on primary molars between 2018 and 2021 at the pediatric dental clinic and had a control radiograph at least 12 months later were enrolled in the study. The chi-squared test was used to determine the differences in success between these two materials. Results. A total of 142 teeth, including 85 (59.9%) first primary molars and 57 (40.1%) second primary molars, in 98 healthy children were evaluated. The mean follow-up period of the teeth included in the study was 585.1±249.4 days. Radiographic success rates for NaOCl and FS groups were 73.8% and 71.0%, respectively, with no statistically significant difference (P>0.05). Internal root resorption (IRR) was the most common cause of radiographic failure in both groups. Conclusion. Radiographic success rates of both materials were similar, and using these materials in primary molar pulpotomy procedures can be recommended in clinical practice.

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“…Physiologic saline, 3% NaOCl, and 2% chlorhexidine are often used as three of the most safe and cost-effective hemostatic agents. These are applied on a sterile cotton pellet, which is placed onto the exposed dental pulp wound for 5-10 min (30). After the bleeding has stopped, the pulp may be considered to have enough vitality to perform a partial pulpotomy procedure.…”

Section: Partial Pulpotomy Of the Exposed Dental Pulpmentioning

confidence: 99%

Regenerative Endodontic Procedures in Immature Permanent Teeth With Dental Trauma: Current Approaches and Challenges

Chun

Zhu

et al. 2022

Front. Dent. Med

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After dental trauma to immature permanent teeth (IPT), there can be pulpitis, necrotic, and periapical periodontitis, which will halt further root development. Traditional endodontic root canal treatments and apexification cannot revitalize the necrotic pulp to revitalize the tooth to promote further root development. As a consequence, IPT with thin dentinal walls can be prone to fracture and if a fracture occurs, the patient will likely suffer the loss of the tooth. In an attempt to save IPT, there has been a growing interest among dentists to use regenerative endodontic procedures (REPs) to revitalize a replace dental pulp to continue root development and strengthen the dentinal walls to help prevent a subsequent loss of the tooth. However, the effectiveness of REPs and the precise methods to successfully accomplish REPs are controversial. Therefore, the objective of this review is to compare the different approaches to REPs in case reports by highlighting their advantages and limitations.

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Clinical and radiographic evaluation of the efficacy of sodium hypochlorite as a haemostatic agent compared with physiologic saline on the success of calcium hydroxide pulpotomies in primary molars: an in vivo study

Cited by 3 publications

References 18 publications

Comparative efficacy of medicaments or techniques for pulpotomy of primary molars: a network meta-analysis

Comparative efficacy of medicaments or techniques for pulpotomy of primary molars: a network meta-analysis

Retrospective analysis of ferric sulfate and sodium hypochlorite pulpotomy procedures in primary molars

Regenerative Endodontic Procedures in Immature Permanent Teeth With Dental Trauma: Current Approaches and Challenges

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