Clinical and Radiographic Outcomes of Regenerative Endodontic Procedures in Traumatized Immature Permanent Teeth: Interappointment Dressing or Single-Visit?

Cerqueira-Neto, Ana Carolina C.L.; Prado, Marina Carvalho; Pereira, Andréa Cardoso; Oliveira, Matheus Lima; Vargas-Neto, Júlio; Gomes, Brenda P. F. A.; Ferraz, Caio Cézar Randi; Almeida, José Flávio Affonso de; Soares, Adriana de Jesus

doi:10.1016/j.joen.2021.07.013

Cited by 18 publications

(19 citation statements)

References 31 publications

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“…During this period, various factors, such as caries, developmental deformity, and trauma, may cause pulp lesions or even pulp necrosis and spread to surrounding tissues. After pulp necrosis, the root development cannot continue in physiological manner [ 12 ]. Because the apical orifice is open, the conventional RCT cannot tightly seal the lumen, so it is not suitable for the control of the infection.…”

Section: Vpt Of Young Permanent Teethmentioning

confidence: 99%

The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective

Shang

Zhang

Zhao

et al. 2022

BioMed Research International

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The indications of vital pulp therapy (VPT) are expanding, which cases are suitable for VPT, and how to improve the success rate of VPT is a problem that often bothers us. The main purpose of VPT is to eliminate pulpitis by promoting the formation of reparative dentin or calcium bridge, so that it can continue to perform various physiological functions, and finally achieve the purpose of preserving pulp vitality and long-term preservation of affected teeth. Pulp capping and pulpotomy are the most common methods for VPT. The research field of VPT has attracted the attention of many scholars, who have studied it from many aspects (such as indications, material selection, operation requirements, and long-term prognosis). This article reviews the recent advances in the techniques of VPT in permanent teeth.

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Section: Vpt Of Young Permanent Teethmentioning

confidence: 99%

The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective

Shang

Zhang

Zhao

et al. 2022

BioMed Research International

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“…Blood clot has been induced as a scaffold in most of the REPs cases, 43,[46][47][48] which is a relatively straightforward and simple approach. It allows integrators on cell surfaces to adhere to fibrous components and selectively adsorb cells, supplying growth factors to promote tissue regeneration.…”

Section: Biological Foundation and Histological Evaluation Of Reps Bi...mentioning

confidence: 99%

Expert consensus on regenerative endodontic procedures

Wei

Yang

Lin³

et al. 2022

Int J Oral Sci

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Regenerative endodontic procedures (REPs) is a biologic-based treatment modality for immature permanent teeth diagnosed with pulp necrosis. The ultimate objective of REPs is to regenerate the pulp-dentin complex, extend the tooth longevity and restore the normal function. Scientific evidence has demonstrated the efficacy of REPs in promotion of root development through case reports, case series, cohort studies, and randomized controlled studies. However, variations in clinical protocols for REPs exist due to the empirical nature of the original protocols and rapid advancements in the research field of regenerative endodontics. The heterogeneity in protocols may cause confusion among dental practitioners, thus guidelines and considerations of REPs should be explicated. This expert consensus mainly discusses the biological foundation, the available clinical protocols and current status of REPs in treating immature teeth with pulp necrosis, as well as the main complications of this treatment, aiming at refining the clinical management of REPs in accordance with the progress of basic researches and clinical studies, suggesting REPs may become a more consistently evidence-based option in dental treatment.

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“…Congruently, REPs which have been employed as a predictable treatment for immature necrotic teeth for years, have slowly seen applications for mature necrotic permanent teeth as well ( El-Kateb et al, 2020 ; Glynis et al, 2021 ). Indeed, the past 2 years have witnessed an incredible increase in publications about REPs citing procedures supporting single visit procedures over multiple visit ones ( Cerqueira-Neto et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Regenerative Endodontics and Minimally Invasive Dentistry: Intertwining Paths Crossing Over Into Clinical Translation

Elnawam

Abdelmougod

Mobarak

et al. 2022

Front. Bioeng. Biotechnol.

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Regenerative endodontic procedures have been described for over a decade as a paradigm shift in the treatment of immature necrotic permanent teeth, owing to their ability to allow root maturation with subsequent enhancement of the tooth’s fracture resistance in addition to the potential for regeneration of vital intracanal tissues. Concomitantly, minimally invasive endodontics is another rising concept with the main concern of preservation of tooth structure. Stemming from their potential to preserve the original tooth structure, both regenerative and minimally invasive endodontics could be considered as two revolutionary sciences with one common goal. Achieving this goal would entail not only employing the appropriate strategies to recreate the ideal regenerative niche but modifying existing concepts and protocols currently being implemented in regenerative endodontics to address two important challenges affecting the outcome of these procedures; conservation of tooth structure and achieving effective disinfection. Therefore, the search for new biomimetic cell-friendly disinfecting agents and strategies is crucial if such a novel integratory concept is to be foreseen in the future. This could be attainable by advocating a new merged concept of “minimally invasive regenerative endodontic procedures (MIREPs),” through modifying the clinical protocol of REPs by incorporating a minimally invasive access cavity design/preparation and biomimetic disinfection protocol, which could enhance clinical treatment outcomes and in the future; allow for personalized disinfection/regeneration protocols to further optimize the outcomes of MIREPs. In this review, we aim to introduce this new concept, its realization and challenges along with future perspectives for clinical implementation.

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Clinical and Radiographic Outcomes of Regenerative Endodontic Procedures in Traumatized Immature Permanent Teeth: Interappointment Dressing or Single-Visit?

Cited by 18 publications

References 31 publications

The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective

The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective

Expert consensus on regenerative endodontic procedures

Regenerative Endodontics and Minimally Invasive Dentistry: Intertwining Paths Crossing Over Into Clinical Translation

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