Clinical and radiological features in three cases of pulmonary involvement from recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis: Cytopathological findings in an unusual case

“…Adult-onset RRP may present at any age, with some preference for occurrence seen in adult male patients in their 30s. 5,7 HPV is the etiologic agent responsible for papillomas in the larynx and trachea. HPV types 6 and 11 are responsible for a significant majority of juvenileonset RRP.…”

“…HPV types 6 and 11 are responsible for a significant majority of juvenileonset RRP. [3][4][5][7][8][9][10] Clinically, the lesions occurring in juvenile-onset RRP often require multiple surgical procedures as compared with adults. Common clinical presentations include hoarseness, dysphonia, aphonia, and airway obstruction.…”

Pulmonary and Extrathymic Mediastinal Tumors

“…Air-fluid levels can be seen with superimposed hemorrhage or infection. Some lesions occasionally resemble dilated bronchi or bronchiectasis but close inspection shows no direct communication to more central bronchi (Williams et al 1994). An intraluminal airway mass with concomitant pulmonary nodules or cavities is highly suggestive of laryngotracheal papillomatosis.…”

“…Children with RRP may present with cough and fever due to atelectasis, consolidation, and bronchiectasis related to airways obstruction and recurrent superinfection (Williams et al 1994). RRP associated with HPV 11 has a more aggressive course and worse prognosis than RRP associated with HPV 6 (Rabah et al 2001).…”

Malignancies of the Pediatric Lower Respiratory Tract

“…While pulmonary involvement is uncommon, papillomas are the most common primary benign tumor of the lower respiratory tract in children (accounting for up to 40 %) [ 5 ]. Distal dissemination may be caused by aerogenous embolization of papilloma particles and can be precipitated by tracheotomy or other airway procedures [ 29 ]. Juvenile-onset RRP has a bimodal peak at 2 and 10 years of age [ 30 ].…”