2020
DOI: 10.3233/xst-200687
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Clinical and radiological features of novel coronavirus pneumonia

Abstract: Recently, COVID-19 has spread in more than 100 countries and regions around the world, raising grave global concerns. COVID-19 transmits mainly through respiratory droplets and close contacts, causing cluster infections. The symptoms are dominantly fever, fatigue, and dry cough, and can be complicated with tiredness, sore throat, and headache. A few patients have symptoms such as stuffy nose, runny nose, and diarrhea. The severe disease can progress rapidly into the acute respiratory distress syndrome (ARDS). … Show more

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Cited by 47 publications
(55 citation statements)
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“…More literature exists on clinical cases with CT imaging in COVID-19, where bilateral GGO and consolidations are described as frequent manifestations in the lungs [ 3 ], with GGO dominating in the early stages, but increasingly showing consolidation as the disease progresses [ 1 , 13 , 16 ]. Changes in lung morphology over time is also described in lung histoarchitecture with changing patterns of diffuse alveolar damage [ 12 ].…”
Section: Discussionmentioning
confidence: 99%
“…More literature exists on clinical cases with CT imaging in COVID-19, where bilateral GGO and consolidations are described as frequent manifestations in the lungs [ 3 ], with GGO dominating in the early stages, but increasingly showing consolidation as the disease progresses [ 1 , 13 , 16 ]. Changes in lung morphology over time is also described in lung histoarchitecture with changing patterns of diffuse alveolar damage [ 12 ].…”
Section: Discussionmentioning
confidence: 99%
“…As described, COVID-19-related interstitial pneumonia can be characterized by a various degree of pulmonary fibrosis, even if the long-term evolution of these alterations is unknown [ 11 , 32 ]. In particular, while in the early stages of COVID-19 pneumonia ground glass opacities represent the main finding of the disease, in more advanced stages the main manifestation is interstitial change of both lungs, such as ïŹbrous cords and reticular opacities [ 33 , 34 ].…”
Section: Pathogenesis Of Covid-19mentioning
confidence: 99%
“…In a follow-up study of 36 patients surviving MERS coronavirus infection, 12 (33%) had radiographic evidence of pulmonary fibrosis; these patients were older and had longer intensive care unit admissions. Given approximately 30% of survivors of SARS and MERS experienced persistent radiological and physiological abnormalities consistent with fibrotic lung disease, the repercussions of COVID-19 could include a large cohort of individuals with pulmonary fibrosis and persistent and potentially progressive physiological impairment [ 33 , 34 ].…”
Section: Pathogenesis Of Covid-19mentioning
confidence: 99%
“…The pandemic caused by the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, also known as 2019-nCoV) has become a major challenge for all countries of the world due to the virus' rapid spread and the lack of a specific, widely-available vaccine to date [1]. Achieving accurate and early detection of the 2019 disease caused by this virus (COVID- 19) has become one of the most important goals in understanding the performance of this virus and positioning medical practitioners to handle the caseload.…”
Section: Introductionmentioning
confidence: 99%