Clinical and serological characteristics of progressive facial hemiatrophy: A case series of 12 patients

Parry–Romberg syndrome: a case with a possible association with Lyme disease

“…Some authors support this hypothesis (13,14), but it is remarkable that several reports from different parts of the world show cases of Parry-Romberg syndrome associated with Lyme disease. We cannot exclude a coincidence; however, the bacteriological and serological evidence and furthermore the interruption of the disease progression after the antibiotic therapy are difficult to ignore without claiming that this association is at least suggestive.…”

“…It is not yet well known and seems to be heterogeneous, including trauma, infection, heredity, vascular malformation, auto-immunity, endocrine disturbances, disturbance of fat metabolism, and sympathetic dysfunction (12). Although the relationship of Borrelia burgdorferi sensu lato infection to Parry-Romberg syndrome has occasionally been reported, the role of Borrelia burgdorferi sensu lato in the development of ParryRomberg syndrome is uncertain (2,(8)(9)(10)(11)(12)(13)(14). In a retrospective study on 12 patients with progressive facial atrophy, Sommer et al (14) reported no association of both disorders.…”

Overlap between linear scleroderma, progressive facial hemiatrophy and immune-inflammatory encephalitis in a paediatric cohort

“…The underlying bone and muscles may become atrophic leading to malocclusion of the jaws, teeth defects and asymmetric tongue. Central nervous system and ophthalmological complications are frequent [15,21].…”

“…The hypothesis that LSCS and PFH are variants of the same disease process is a long-standing controversy [10,15,18]. Moreover, overlap between these diseases and encephalitis has been reported [1,13,14].…”

“…Moreover, overlap between these diseases and encephalitis has been reported [1,13,14]. The pathogenesis of these diseases remains a matter of discussion [15,18].…”