Clinical and therapeutic features of polymorphous low-grade adenocarcinoma

Histologic Transformation of Polymorphous Low-Grade Adenocarcinoma of Salivary Gland

“…Exploratory surgery was performed, and a large lesion extending from the left maxillary antrum through the ethmoid sinuses and into the ORIGINAL ARTICLE were associated with multiple recurrences, and regional lymph node metastases occurred at some point in 9%. 2 In a lesion involving the parotid gland that locally recurred after 6 years, the authors noted that the histologic appearance of the recurrence was generally similar to that of the primary lesion; however, cells with large nuclei and prominent nucleoli were more apparent in areas of the recurrent tumor. 24 Colmenero et al 24 described a greater proportion of cells with clear cytoplasm in 3 recurrent cases.…”

Salivary Gland Neoplasia: A Review for the Practicing Pathologist

“…The recurrence rate from a literature review and a large AFIP series is 9 -17%, of those 40% were multiple recurrences (72,76). Roughly 9% of PLGA have metastasized to regional lymph nodes.…”

Nano-hydroxyapatite and its contemporary applications

“…Buccal and labial mucosa, alveolar mucosa, retromolar trigone, tongue, floor of mouth and parotid gland are other sites of occurrence in that order. [6,7] Uncommon locations include lacrimal glands, nasopharynx, nasal cavity, tonsillar region and paranasal sinuses. [5][6][7] We present a rare case of PLGA of retromolar area highlighting various diagnostic challenges caused by the overlap of clinical and microscopic features between PLGA and other salivary gland neoplasms and discuss current management strategies.…”