Clinical and videoEEG findings in a girl with juvenile moyamoya disease

Kaciński, Marek; Kubik, Alicja; Kroczka, Sławomir; Gergont, Aleksandra

doi:10.1016/j.braindev.2007.03.004

Cited by 7 publications

(5 citation statements)

References 6 publications

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“…In cases of more severe infection, such as neuroborreliosis, intravenous (IV) ceftriaxone is typically preferred due to its favorable dosing schedule [11]. However, IV cefotaxime and IV penicillin G have also been used successfully [10,11]. Doxycycline is not recommended in children under eight years of age due to the risk of dental staining, although some evidence suggests benefits may outweigh risks, as seen in our case where doxycycline led to significant clinical improvement [5,8].…”

Section: Discussionmentioning

confidence: 92%

“…Current guidelines suggest several medications for managing both early and late Lyme neuroborreliosis, including penicillin G, ceftriaxone, cefotaxime, or doxycycline [10]. However, the specific dosage, frequency, route of administration, and duration of treatment remain topics of debate [10,11].…”

Section: Discussionmentioning

confidence: 99%

“…Treatment options for pediatric Lyme disease vary based on the severity of the infection and the patient's age [10,11]. For early uncomplicated Lyme disease, outpatient oral therapy with doxycycline is recommended [10].…”

Section: Discussionmentioning

confidence: 99%

“…In children under eight years of age, amoxicillin is the preferred choice. In cases of more severe infection, such as neuroborreliosis, intravenous (IV) ceftriaxone is typically preferred due to its favorable dosing schedule [11]. However, IV cefotaxime and IV penicillin G have also been used successfully [10,11].…”

Section: Discussionmentioning

confidence: 99%

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Rare Presentation of Pediatric Nervous System Lyme Disease: A Case Report

Khurtsilava,

kanjaradze,

Tsirdava

et al. 2024

Cureus

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Lyme disease is a multisystem infectious disease. It is caused by the dissemination of Borrelia spirochetes after a tick bite. It has various manifestations across different age groups. Commonly involved organs are the skin, joints, and nervous system. Nervous system Lyme disease has a wide spectrum of manifestations. While facial nerve palsy and subacute meningitis are commonly observed in the pediatric population, our case report reveals an uncommon manifestation of the nervous system Lyme disease. A four-year-old patient exhibited mood changes, behavioral issues, and generalized tonic-clonic seizures. Extensive diagnostic workup initially yielded no clear cause until positive IgM and IgG serology for Borrelia suggested Lyme neuroborreliosis. This differs from the usual symptoms seen in pediatric cases. The patient responded positively to antibiotic treatment, but persistent post-treatment behavioral issues raised questions about potential long-term effects. This case underscores the importance of considering Lyme disease in atypical presentations, even in non-endemic areas, necessitating an adaptable diagnostic approach for improved outcomes, especially in pediatric patients. Continued research into the comprehensive understanding of Lyme disease in pediatric patients is crucial.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Rare Presentation of Pediatric Nervous System Lyme Disease: A Case Report

Khurtsilava,

kanjaradze,

Tsirdava

et al. 2024

Cureus

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“…Many reports have not confirmed a significant increase in IL-6 levels [64,67,69,71,72] and only two confirmed significant differences [65,70]. In the study of IL-1β, the number of reports with confirmed significant differences [69,70,73] and those with no significant increase [63,65,67,74] were similar.…”

Section: Examination Of Serum or Plasma Cytokines During Migraine Att...mentioning

confidence: 98%

Experimental and Clinical Investigation of Cytokines in Migraine: A Narrative Review

Yamanaka,

Hayashi,

Morishita

et al. 2023

IJMS

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The role of neuroinflammation in the pathophysiology of migraines is increasingly being recognized, and cytokines, which are important endogenous substances involved in immune and inflammatory responses, have also received attention. This review examines the current literature on neuroinflammation in the pathogenesis of migraine. Elevated TNF-α, IL-1β, and IL-6 levels have been identified in non-invasive mouse models with cortical spreading depolarization (CSD). Various mouse models to induce migraine attack-like symptoms also demonstrated elevated inflammatory cytokines and findings suggesting differences between episodic and chronic migraines and between males and females. While studies on human blood during migraine attacks have reported no change in TNF-α levels and often inconsistent results for IL-1β and IL-6 levels, serial analysis of cytokines in jugular venous blood during migraine attacks revealed consistently increased IL-1β, IL-6, and TNF-α. In a study on the interictal period, researchers reported higher levels of TNF-α and IL-6 compared to controls and no change regarding IL-1β levels. Saliva-based tests suggest that IL-1β might be useful in discriminating against migraine. Patients with migraine may benefit from a cytokine perspective on the pathogenesis of migraine, as there have been several encouraging reports suggesting new therapeutic avenues.

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Electroencephalography (EEG) in Moyamoya Disease

Chae

Kim

2010

Moyamoya Disease Update

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Clinical and videoEEG findings in a girl with juvenile moyamoya disease

Cited by 7 publications

References 6 publications

Rare Presentation of Pediatric Nervous System Lyme Disease: A Case Report

Rare Presentation of Pediatric Nervous System Lyme Disease: A Case Report

Experimental and Clinical Investigation of Cytokines in Migraine: A Narrative Review

Electroencephalography (EEG) in Moyamoya Disease

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