Clinical and virological characteristics of SARS-CoV-2 Omicron BA.2.2 variant outbreaks during April to May, 2022, Shanghai, China

Ao, Yuanyun; Li, Jingjing; Wei, Zhongqiu; Wang, Zhong Lin; Tian, He; Qiu, Yudong; Fu, Xiaomin; Ma, Wenhui; Li, Liting; Zeng, Mei; Xu, Jin

doi:10.1016/j.jinf.2022.07.027

Cited by 22 publications

(19 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to previous findings ( Ao et al, 2022 ; Butt et al, 2022 ), Omicron BA.2 variants caused milder disease manifestations in children. Our study reported a higher proportion of asymptomatic infections (79.7%) than mild symptomatic infections (20.3%) in the entire study population.…”

Section: Discussionsupporting

confidence: 91%

Efficacy of Lianhua Qingwen for children with SARS-CoV-2 Omicron infection: A propensity score-matched retrospective cohort study

Jin

et al. 2023

Phytomedicine

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 91%

Efficacy of Lianhua Qingwen for children with SARS-CoV-2 Omicron infection: A propensity score-matched retrospective cohort study

Jin

et al. 2023

Phytomedicine

View full text Add to dashboard Cite

“…2). Twenty-two studies were from populations primarily of European ancestry [8,32,[40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59], eight studies on East Asians [60][61][62][63][64][65][66][67], three studies on South Asians [68][69][70], three studies on Latinos [71][72][73], four studies on populations in Africa [74][75][76][77], and one study from West Asia (Turkey [78]). The location of studies, with the prevalence indicated by the color intensity, and the cohort size indicated by the size of the circles, shows that Western countries report the highest prevalence, while studies from East Asia and Africa report the lowest prevalence (Fig.…”

Section: Properties Of Studiesmentioning

confidence: 99%

“…2). Twenty-five studies were from populations primarily of European ancestry [9,30,, seventeen studies on East Asians [61][62][63][64][65][66][67][68][69][70][71][72][73][74][75][76][77] (note that one of these studies, [75], reports on the same cohort as [74], and therefore was removed from the meta-analysis), eight studies on South Asians [79][80][81][82][83][84][85][86], four studies on Latinos/Hispanics [87][88][89][90], five studies on populations in Africa [91][92][93][94][95], and three studies from the Middle East [96][97][98]. The location of studies, with the prevalence indicated by the color intensity, and the cohort size indicated by the size of the circles, shows that Western countries report the highest prevalence, while studies from East Asia and the Middle East report the lowest prevalence (Fig.…”

Section: Properties Of Studiesmentioning

confidence: 99%

Prevalence of Olfactory Dysfunction with the Omicron Variant of SARS-CoV-2: A Systematic Review and Meta-analysis

Bartheld

Wang

2022

Preprint

View full text Add to dashboard Cite

The omicron variant is thought to cause less olfactory dysfunction than previous variants of SARS-CoV-2, but the reported prevalence differs greatly between populations and studies. Our systematic review and meta-analysis provide information about regional differences in prevalence as well as an estimate of the global prevalence of olfactory dysfunction based on 41 studies reporting on nearly 600,000 patients infected with the omicron variant. Our estimate of the omicron-induced prevalence of olfactory dysfunction in populations of European ancestry is 11.6%, while it is significantly lower in all other populations, at 2.9-5.4%. When ethnic differences and population sizes are taken into account, the global prevalence of omicron-induced hyposmia in adults is estimated at 5.2%. Omicron's effect on olfaction is 3-4fold lower than that of the alpha or delta variant, according to previous meta-analyses and our analysis of studies that directly compared prevalence of olfactory dysfunction between omicron and previous variants. The profile of prevalence differences between ethnicities mirrors the results of a recent genome-wide association study that implicated a gene locus encoding an odorant-metabolizing enzyme, UDP glycosyltransferase, to be linked to the extent of COVID-related loss of smell. Our analysis is consistent with the hypothesis that this enzyme contributes to the observed population differences.

show abstract

“…The recommended schedule for the primary vaccine series was two doses with an interval of 3–4 weeks. Despite the implementation of strict non-pharmaceutical interventions (NPI), symptom-based active monitoring, contact quarantine, and mass vaccination in Shanghai, the importation of the Omicron variant BA.2 led to the first large outbreak of COVID-19 in Shanghai between March and May 2022 [4]. As of 31 May 2022, approximately 626,000 cases of COVID-19 were reported [5].…”

Section: Introductionmentioning

confidence: 99%

Epidemiological characteristics of paediatric Omicron infection during the outbreak of SARS-CoV-2 infection during March–May in 2022 in Shanghai, China

Chang

Zhang²,

Su³

et al. 2023

Epidemiol. Infect.

Self Cite

View full text Add to dashboard Cite

This study aims to understand the epidemiological characteristics of SARS-CoV-2 infection in the paediatric population during the outbreak of the Omicron variant in Shanghai. We retrospectively analysed the population-based epidemiological characteristics and clinical outcome of SARS-CoV-2 Omicron variant infection in children in Minhang District, Shanghai, based on the citywide surveillance system during the outbreak period in 2022 (March to May). During this time, a total of 63,969 cases of SARS-CoV-2 infection were notified in Minhang District, out of which 4,652 (7.3%) were children and adolescents <18 years. The incidence rate of SARS-CoV-2 infections in children was 153 per 10,000. Of all paediatric cases, 50% reported to be clinically symptomatic within 1–3 days after PCR confirmation by parents or themselves, with 36.3% and 18.9% of paediatric cases reporting fever and cough. Also, 58.4% of paediatric cases had received at least one dose of the COVID-19 vaccine and 52.1% had received two doses of the COVID-19 vaccination. Our findings are informative for the implementation of appropriate measures to protect children from the threat of SARS-CoV-2 infection.

show abstract

Clinical and virological characteristics of SARS-CoV-2 Omicron BA.2.2 variant outbreaks during April to May, 2022, Shanghai, China

Cited by 22 publications

References 9 publications

Efficacy of Lianhua Qingwen for children with SARS-CoV-2 Omicron infection: A propensity score-matched retrospective cohort study

Efficacy of Lianhua Qingwen for children with SARS-CoV-2 Omicron infection: A propensity score-matched retrospective cohort study

Prevalence of Olfactory Dysfunction with the Omicron Variant of SARS-CoV-2: A Systematic Review and Meta-analysis

Epidemiological characteristics of paediatric Omicron infection during the outbreak of SARS-CoV-2 infection during March–May in 2022 in Shanghai, China

Contact Info

Product

Resources

About