2018
DOI: 10.1001/jamaoto.2018.2054
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Clinical Application of 3-Dimensional Printing Technology for Patients With Nasal Septal Deformities

Abstract: IMPORTANCE Studies have shown the controllability and porosity of polycaprolactone as well as the use of 3-dimensional (3-D) printing for nasal reconstruction in animal models. The utility of polycaprolactone with 3-D technology in nasal cartilaginous framework reconstruction in humans remains unknown. OBJECTIVE To investigate the safety and efficacy of 3-D printed, bioresorbable polycaprolactone nasal implants. DESIGN, SETTING, AND PARTICIPANTS This multicenter clinical trial comprised 20 patients with caudal… Show more

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Cited by 36 publications
(39 citation statements)
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“…PCL is a biocompatible and biodegradable synthetic polymer with the proper mechanical strength and durability. PCL has been widely used for drug delivery devices and in the tissue engineering field because it is biocompatible and slowly degrades in the body . The long‐term biodegradability of PCL mesh can resist deformations because of contractions of the skin and scars that occur during the healing process .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…PCL is a biocompatible and biodegradable synthetic polymer with the proper mechanical strength and durability. PCL has been widely used for drug delivery devices and in the tissue engineering field because it is biocompatible and slowly degrades in the body . The long‐term biodegradability of PCL mesh can resist deformations because of contractions of the skin and scars that occur during the healing process .…”
Section: Discussionmentioning
confidence: 99%
“…The advantage of 3D printing is the capability to not only produce patient‐specific scaffolds, but also design homogeneous standardized microporous composite scaffolds. Therefore, the mechanical properties, degree of fibrovascular ingrowth, and suture friendly microporous design can be controlled by the 3D printing technique . Three‐dimensional printing is especially advantageous in creating patient specific scaffolds, as the design and printing process is able to generate structures that are not otherwise possible using standard manufacturing techniques.…”
Section: Discussionmentioning
confidence: 99%
“…163 In nasal septum deviation, a stent to correct the deviation has also been accurately manufactured by 3D printing. 164 A 3D-printed, porous titanium scaffold can also act as the nasal cartilage and was combined with a skin flap for nasal reconstruction (Fig. 8b).…”
Section: Virtual Surgical Planningmentioning
confidence: 99%
“…At present, the technology of using 3D manufacturing technology to customize personalized ear-nose prosthesis is relatively mature [ 110 , 112 , 113 ]. After collecting data with photogrammetric equipment, a portable desktop 3D printer can produce high-quality silicone soft prostheses in a short time [ 114 , 115 ]. Compared with traditional prostheses, 3D printed ear and nose repair prostheses have huge advantages in terms of material design flexibility and personalized size customization [ 115 , 116 ].…”
Section: Development and Application Of 3d Manufacturing Technologmentioning
confidence: 99%
“… Examples of the applications of three-dimensional (3D) manufacturing technology in plastic and cosmetic surgery [ 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 ]. ( A ) The 3D manufacturing technology for temporomandibular joint reconstruction [ 111 ].…”
Section: Figurementioning
confidence: 99%