Clinical application of intratumoral blood flow study in patients with endometrial carcinoma

Cheng, Wen‐Fang; Chen, Tzer‐Ming; Chen, Chi‐An; Wu, Chih‐Cheng; Huang, Kuo-Yu; Hsieh, Chang Hsun; Hsieh, F. Y.

doi:10.1002/(sici)1097-0142(19980515)82:10<1881::aid-cncr10>3.3.co;2-d

Cited by 16 publications

(16 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some studies have assessed the blood flow characteristics of the uterine artery, 17,11 whereas others have evaluated directly the blood flow characteristics of intratumoral arteries. 26,27 Cheng et al 26 have shown the usefulness of TV-CDU in predicting myometrial tumor spread by using blood flow resistance indices. 28 However, Develioglu et al 17 have shown the unreliability of predicting tumor spread using such indices.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Section

Özdemir¹,

Çelık²,

Emlik

et al. 2009

Int J Gynecol Cancer

View full text Add to dashboard Cite

Transvaginal sonography with concomitant TV-UCD is low-cost, easily performed, and repeated technique for particularly deep myometrial invasion. Because of its high costs and time-consuming, MRI may be recommended in the cases with poor quality of TVS. Because depending solely on imaging methods could lead to insufficient treatment schedules, intraoperative frozen section should also be performed for myometrial assessment.

show abstract

Section: Discussionmentioning

confidence: 99%

Assessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Section

Özdemir¹,

Çelık²,

Emlik

et al. 2009

Int J Gynecol Cancer

View full text Add to dashboard Cite

show abstract

“…In some studies, angiogenesis was directly related with tumour grade [2,46,110], depth of myometrial invasion [2,46,85], lymphvascular space invasion [46], lymph-node involvement [110] and stage of disease [85,110]. Interestingly, Cheng et al [17] reported comparable results in patients with endometrial carcinoma assessed for MVD pre-operatively using colour Doppler ultrasound. Yet other studies failed to establish any significant association between high MVD and histopathological parameters [6,33].…”

Section: Angiogenesismentioning

confidence: 99%

Prognostic aspects on endometrial hyperplasia and neoplasia

Sivridis

Giatromanolaki

2001

Virchows Arch

View full text Add to dashboard Cite

There are various forms of endometrial hyperplasia which, in terms of prognosis and therapy, can be subdivided into those having cytological atypia and those lacking this feature. The former may progress into invasive endometrial malignancy through a transitional non-invasive stage. This is a continuous process and, as a result, the distinction between an atypical hyperplasia and an intraepithelial adenocarcinoma (IEA) or an adenocarcinoma with stromal invasion is not histologically reproducible. The concept of endometrioid neoplasia, which includes the entire spectrum of the aforementioned proliferating endometrial lesions, was introduced. Adenocarcinomas arising from an atypical hyperplasia are invariably of the endometrioid cell type, whereas those developing from an atrophic endometrium may be either of the endometrioid or of the non-endometrioid cell type. Endometrioid adenocarcinomas arising through the hyperplasia-neoplasia sequence are oestrogen induced and tend to be well differentiated and less invasive of the myometrium, lack lymphatic and metastatic involvement and have an excellent prognosis. Oestrogen-induced adenocarcinomas are also endometrioid, arising from an atrophic or a rather weakly proliferating endometrium, but these neoplasms are frequently of higher histological grade and have a somewhat less favourable prognosis. Finally, endometrial carcinomas of the non-endometrioid cell type, mainly serous papillary and clear cell carcinomas, are non-oestrogen induced, non-hyperplasia associated and show adverse aggressive histological features and an extremely poor prognosis. The antigenic characteristics and the molecular events associated with the development of these forms of endometrial malignancy are distinct and allow the description of, at least, two pathogenetic types of endometrial carcinoma.

show abstract

“…Im Vergleich zur Sonographie und zum CT stellt das MRT, vor allem mit Kontrastmittelanwendung, die derzeit beste Möglichkeit zur Evaluation der myometranen und zervikalen Invasion dar[5,32,54,64,67,90]. Zusätzlich können hiermit direkt pelviner und paraaortaler Lymphknotenbefall sowie abdominale Metastasen dargestellt werden[64,93].Auch beim präoperativen Staging sind gewisse Vorteile in der Anwendung der Farbdopplersonographie zu erkennen, allerdings ist die derzeitige Datenlage noch nicht ausreichend, um eine definitive Aussage zu treffen [1,18,19,24,38,59].…”

unclassified

Diagnostik und präoperatives Staging des Endometriumkarzinoms mittels transvaginaler Sonographie - eine Übersicht

Nk¹,

Rehn²,

Thanner³

et al. 2006

Zentralbl Gynakol

View full text Add to dashboard Cite

Endometrial carcinoma is the most common malignant tumor of the female genital tract. The major non-invasive diagnostic method is ultrasound. Endometrial thickness (double layer) is measured by transvaginal sonography. The cut-off value in patients with postmenopausal bleeding is still controversial, although in patients with endometrial thickness below 4 mm (or 5 mm respectively), malignancy can be excluded with high probability. If the endometrium measures more than 4 mm (or more than 5 mm respectively) or the patient presents with continuous bleeding, hysteroscopy and curettage should be performed in order to obtain histologic diagnosis. Sonographic findings like structure and demarcation of the endometrium increase diagnostic specificity only when combined with the measurement of endometrial thickness. Measuring the fluid within the uterine cavity does not seem to be useful in differentiating malignant from benign disorders. The extent of surgery depends on the preoperative estimation of the tumor stage which is particularly important for elder patients with increased morbidity. Transvaginal sonography has not been widely accepted to predict the depth of myometrial invasion or cervical infiltration. Although promising studies exist, additional examinations have to be done in order to determine the role of transvaginal sonography beside other methods (CT, MRT). This article on transvaginal ultrasound reviews current data on the method's capacity to identify endometrial cancer and to diagnose the depth of invasion.

show abstract

Clinical application of intratumoral blood flow study in patients with endometrial carcinoma

Cited by 16 publications

References 1 publication

Assessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Section

Assessment of Myometrial Invasion in Endometrial Cancer by Transvaginal Sonography, Doppler Ultrasonography, Magnetic Resonance Imaging and Frozen Section

Prognostic aspects on endometrial hyperplasia and neoplasia

Diagnostik und präoperatives Staging des Endometriumkarzinoms mittels transvaginaler Sonographie - eine Übersicht

Contact Info

Product

Resources

About