Clinical Application of the COPD Assessment Test

de-Torres, Juan P.; Marı́n, José Marı́a; Martínez-González, Cristina; Lucas-Ramos, Pilar de; Mir-Viladrich, Isabel; Cosío, Borja G.; Peces-Barba, Germán; Rubio, Myriam Calle; Solanes-García, Ingrid; Balbín, R. Agüero; Diego-Damia, Alfredo de; Feu-Collado, Nuria; Alfageme, Inmaculada; Irigaray, Rosa; Balcells, Eva; Casanovas, Antonia Llunell; Iturri, Juan Bautista Gáldiz; Royo, Margarita Marín; Soler-Cataluña, Juan José; Lόpez-Campos, José Luís; Soriano, Joan B.; Casanova, Ciro

doi:10.1378/chest.13-2246

Cited by 20 publications

(7 citation statements)

References 18 publications

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“…Other studies have evaluated the longitudinal changes in CAT values, indicating a variability in the CAT scores among patients with stable COPD similar to that for the MRC scale score. 18 Second, the standardized questionnaire used was limited in the number of variables, to make the project affordable. Consequently, several variables, including disease phenotypes or exercise capacity, were not evaluated.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

Lόpez-Campos¹,

Villar²,

Calero-Acuña³

et al. 2015

COPD

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BackgroundThe COPD Assessment Test (CAT) has been recently developed to quantify COPD impact in routine practice. However, no relationship with other measures in the Global Initiative for Obstructive Lung Disease (GOLD) strategy has been evaluated. The present study aimed to evaluate the relationship of the CAT with other GOLD multidimensional axes, patient types, and the number of comorbidities.MethodsThis was a cross-sectional analysis of the Clinical presentation, diagnosis, and course of chronic obstructive pulmonary disease (On-Sint) study. The CAT score was administered to all participants at the inclusion visit. A GOLD 2011 strategy consisting of modified Medical Research Council scale (MRC) scores was devised to study the relationship between the CAT, and GOLD 2011 axes and patient types. The relationship with comorbidities was assessed using the Charlson comorbidity index, grouped as zero, one to two, and three or more.ResultsThe CAT questionnaire was completed by 1,212 patients with COPD. The CAT maintained a relationship with all the three axes, with a ceiling effect for dyspnea and no distinction between mild and moderate functional impairment. The CAT score increased across GOLD 2011 patient types A–D, with similar scores for types B and C. Within each GOLD 2011 patient type, there was a considerably wide distribution of CAT values.ConclusionOur study indicates a correlation between CAT and the GOLD 2011 classification axes as well as the number of comorbidities. The CAT score can help clinicians, as a complementary tool to evaluate patients with COPD within the different GOLD patient types.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

Lόpez-Campos¹,

Villar²,

Calero-Acuña³

et al. 2015

COPD

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“…These will be completed independently with a researcher on hand to resolve any difficulties. The CRQ-SR, CAT, Leicester Cough Questionnaire, London Chest Activity of Daily Living questionnaire, Multidimensional Dyspnoea Profile, and Hospital Anxiety and Depression Scale will be used [18, 21–24]. All questionnaires will be scored individually and repeated at follow-up (8 weeks).…”

Section: Methods and Analysismentioning

confidence: 99%

A randomised controlled trial to investigate the use of high-frequency airway oscillations as training to improve dyspnoea in COPD

et al. 2019

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IntroductionChronic obstructive pulmonary disease (COPD) is characterised by expiratory flow limitation resulting in symptomatic dyspnoea, sputum retention and ventilation heterogeneity. Changes in breathing mechanics affect the ability of respiratory muscles to respond to the ventilatory demands, increasing the sensation of dyspnoea. A high-frequency airway oscillating device has been developed to combine respiratory muscle training and oscillations to improve dyspnoea and sputum retention within COPD.Methods and analysisPatients with symptomatic COPD (Medical Research Council Breathlessness scale grade ≥2) will be recruited to a double-blind, randomised, sham-controlled trial. Both groups will follow an 8-week intervention phase using the device three times per day for 5 min at a time. This will be recorded in a self-reported diary. The device applies a flow resistive load and oscillations for combined training. Those receiving the sham device will follow the same protocol; however, the mechanism of action will be removed from the device. Improvements in the Chronic Respiratory Questionnaire-Dyspnoea domain will be the primary outcome measure. Secondary outcomes will explore respiratory muscle function, health-related quality of life, exercise capacity and physical activity. The Lung Clearance Index will be an exploratory outcome. Outcomes will be explored using the most appropriate statistical test, dependent on the sample distribution. Focus groups will be an exploratory outcome and analysed by thematic analysis.Ethics and disseminationEthical approval has been obtained from the East Midlands-Leicester South Research Ethics Committee and the trial has been registered through the ISRCTN Registry. The study results will be disseminated to the appropriate stakeholders through presentations, conferences and peer-reviewed journals.

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“…Currently there are no long-term data about changes in CAT and CCQ over time, although these are now being collected. One study of a two timepoint measurement of CAT scores shows clear evidence of a regression to the mean effect so it has little value in this context 62 . Mapping CAT scores from SGRQ scores in a number of longitudinal studies suggests that the average CAT change will be around +1 unit per year.…”

Section: What Added Value Does Health Status Measurement Offer the CLmentioning

confidence: 99%

Health-Related Quality of Life in Chronic Obstructive Pulmonary Disease

Jones¹

2016

BRN

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Health-related quality of life is a clinical outcome that is unique to each individual. It can be assessed subjectively by a clinician, but cannot be measured in a standardised manner. In contrast, health status which is a marker of impaired health-related quality of life, is measureable and such measurements are now performed routinely in clinical trials to estimate the size of treatment benefit. Outside the setting of clinical trials, health status questionnaires have shed important insights into a number of areas of chronic obstructive pulmonary disease, particularly in terms of symptomatic progression over time, which appears to be confined largely to effects on physical activity and psycho-social areas of health-related quality of life, rather than specific respiratory symptoms. Development of short simple instruments has brought health status measurement into routine practice where it may be particularly useful for baseline assessment, monitoring trends, and assessment of recovery after acute events such as exacerbations or hospitalisation.

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Clinical Application of the COPD Assessment Test

Cited by 20 publications

References 18 publications

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

A randomised controlled trial to investigate the use of high-frequency airway oscillations as training to improve dyspnoea in COPD

Health-Related Quality of Life in Chronic Obstructive Pulmonary Disease

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