Clinical application of tissue‐engineered transplants. Part I: mucosa

Abstract

Tissue-engineered oral mucosa fulfils the requirements for clinical routine. With view to healing time and outcome it does not appear to be superior to regular harvested oral mucosa transplants. Because of a smaller harvesting defect and primary wound closure at the actual operation site the patients' convenience is increased. Thus this method reduces morbidity and advances the quality of life.

In vivo behavior of complete human oral mucosa equivalents: characterization in athymic mice

“…The pattern was homogeneous during the first week, but thereafter only some cells showed immunostaining. Our findings are consistent with those reported by other authors (5,20), which suggests that this filament is present in both mesenchymal cells and undifferentiated keratinocytes.…”

Augmentation Vaginoplasty of Colonic Neovagina Stricture Using Oral Mucosa Graft

“…8,9 Early studies on growing autologous oral mucosa, and even vaginal mucosa, are promising, but more work is needed before such tissue engineering technology can be considered anything but experimental. 10,11 Cloacal exstrophy is a rare, complex anomaly classically consisting of an omphalocele, imperforate anus, exstrophy of 2 small hemibladders, a lateral cecal fissure, and ambiguous genitalia. 12 Surgical literature, especially literature evaluating gynecologic outcomes, in the cloacal exstrophy population is limited.…”

In vitro study on proliferation kinetics of oral mucosal keratinocytes

“…In comparison, other study groups used larger specimens, ranging from 4 mm up to 5 cm in the largest dimension. [20][21][22][23][24] The explantation technique used for isolation of keratocytes in this present study, based on …”