Clinical Applications of Hybrid PET/MRI in Neuroimaging

Garibotto, Valentina; Heinzer, Susanne; Vulliémoz, Serge; Guignard, Romain; Wissmeyer, Michael; Seeck, Margitta; Lövblad, Karl-Olof; Zaidi, Habib; Ratib, Osman; Vargas, Maria Isabel

doi:10.1097/rlu.0b013e3182638ea6

Cited by 102 publications

(80 citation statements)

References 24 publications

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“…Both modalities provide complementary information about the function, metabolism, and anatomy of the brain. The outstanding role of PET imaging in detecting biochemical and molecular changes much earlier, before structural changes or clinical symptoms appear, has been described in numerous studies (55)(56)(57). fMR with DWI and MR spectroscopy has become an important noninvasive and nonradioactive tool for measuring brain activity by detecting, for instance, hemodynamic changes (in blood oxygenation and flow) induced by regional changes in neuronal activity (1,58).…”

Section: Potential Applications In Neuroimagingmentioning

confidence: 99%

Potential Pediatric Applications of PET/MR

et al. 2014

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Medical imaging with multimodality and whole-body technologies has continuously improved in recent years. The advent of combined modalities such as PET/CT and PET/MR offers new tools with an exact fusion of molecular imaging and high-resolution anatomic imaging. For noninvasive pediatric diagnostics, molecular imaging and whole-body MR have become important, especially in pediatric oncology. Because it has a lower radiation exposure than PET/CT, combined PET/MR is expected to be of special use in pediatric diagnostics. This review focuses on possible pediatric applications of PET/MR hybrid imaging, particularly pediatric oncology and neurology but also the diagnosis of infectious or inflammatory diseases.

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Section: Potential Applications In Neuroimagingmentioning

confidence: 99%

Potential Pediatric Applications of PET/MR

et al. 2014

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“…As such, combined PET-MR reins in the synergy and helps in personalized radiotherapy treatment planning in brain tumors. 51 In the radiotherapy treatment planning of glioblastoma multiforme (GBM), MR imaging is routinely used for GTV delineation. One of the caveats in using MR imaging for delineating glioma tumor boundaries is that MR imaging is unreliable mainly because of the inherently infiltration nature of GBM and the lack of distinction between glioma and surrounding edema with MR imaging.…”

Section: Role Of Hybrid Pet-mr For Target Volume Delineation Of Brainmentioning

confidence: 99%

Novel Quantitative Techniques in Hybrid (PET-MR) Imaging of Brain Tumors

Senthamizhchelvan

Zaidi

2013

PET Clinics

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“…This may reflect the difficulty in localizing and resecting the epileptogenic zone [60]. In order to improve the radiographic detection of epileptogenic lesions, more advanced imaging techniques have been used such as 7T MRI, volumetric analysis, Diffusion Tensor Imaging (DTI), arterial spin labeling and PET [38,[66][67][68][69][70][71][72][73][74]. However, it is currently unknown if such techniques willimprove outcomes.…”

Section: Non-pharmacological Treatmentmentioning

confidence: 99%

Review of Epilepsy - Etiology, Diagnostic Evaluation and Treatment

Shin¹,

Jewells²,

Hadar³

et al. 2014

Int J Neurorehabilitation Eng

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Epilepsy is the fourth most common neurological disorder in the US, affecting nearly 2.5 million Americans. The economic impact of epilepsy represents estimated direct and indirect costs of 12.5 billion dollars per year. Patients with this disorder experience increased morbidity and mortality with long term fatality rates of 24%. Multiple diagnostic tools are used to identify and classify the seizure type/syndrome, etiology and localization of seizures, including electroencephalogram (EEG), magnetic resonance imaging (MRI), positron emission tomography (PET), and single photon emission computed tomography (SPECT), magneto encephalogram (MEG), and neuropsychiatric testing. Despite 29 different antiepileptic medications that are available in the US, one third of patients remain refractory to pharmacological treatment. In these intractable epilepsy patients, non-pharmacological treatments can be considered. Commonly used non-pharmacological treatment options for epilepsy include epilepsy surgery, neurostimulation therapy, and diet therapy. Review of Epilepsy -Etiology, Diagnostic Evaluation and Treatment

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Clinical Applications of Hybrid PET/MRI in Neuroimaging

Cited by 102 publications

References 24 publications

Potential Pediatric Applications of PET/MR

Potential Pediatric Applications of PET/MR

Novel Quantitative Techniques in Hybrid (PET-MR) Imaging of Brain Tumors

Review of Epilepsy - Etiology, Diagnostic Evaluation and Treatment

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