Clinical applications of radionuclide imaging in the evaluation and management of patients with congenital heart disease

Partington, Sara L.; Valente, Anne Marie; Landzberg, Michael J.; Grant, Frederick D.; Carli, Marcelo F. Di; Dorbala, Sharmila

doi:10.1007/s12350-015-0185-5

Cited by 20 publications

(7 citation statements)

References 65 publications

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“…Understanding the prior surgical and percutaneous procedures that the patient may have undergone helps to distinguish normal from true pathologic variants because prosthetic material and atypical locations of outflow tracts can mimic myocardial infarcts. 12 Myocardial perfusion PET imaging In general, the clinical indications for PET MPI in children (Fig. 3) are similar to those for SPECT MPI.…”

Section: Cardiovascular Indication and Applicationsmentioning

confidence: 84%

Practical Indication-Based Pediatric Nuclear Medicine Studies

Kwatra

Sarma

Lee

2017

Radiologic Clinics of North America

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Section: Cardiovascular Indication and Applicationsmentioning

confidence: 84%

Practical Indication-Based Pediatric Nuclear Medicine Studies

Kwatra

Sarma

Lee

2017

Radiologic Clinics of North America

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“…Cardiac positron emission tomography offers the possibility of performing low‐dose radionuclide imaging to assess coronary blood flow reserve . Magnetic resonance imaging is a valid technique for coronary flow reserve and myocardial perfusion assessment .…”

Section: Resultsmentioning

confidence: 99%

Review findings included diminished coronary flow reserve after surgery in children with congenital heart disease and inflammation

2018

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Aim: The aim of this review was to develop a deeper knowledge of the physiology of coronary blood flow and coronary flow reserve in young patients with congenital heart disease and inflammatory diseases. Methods: We searched for papers published in English on coronary blood flow and coronary flow reserve using the PubMed and Google search databases. This identified 42 papers extending back to 1976 and a book from 2008 (Davis et al. Microcirculation. Boston, MA: Elsevier, 2008: 161-284).Results: Our review showed that the implications of coronary blood flow and coronary flow reserve in paediatric patients with congenital heart disease and inflammatory diseases are still not fully understood. However, a key finding was that coronary flow reserve was diminished in patients with congenital heart disease and inflammation after surgery, with or without a cardiopulmonary bypass. Other findings discussed by this review relate to volume and pressure overload in acyanotic congenital heart disease, reduced myocardial perfusion and cyanotic congenital heart disease. Conclusion:We still have much to discover about paediatric patients with congenital heart disease and inflammatory diseases. Understanding the pathophysiology of coronary blood flow could help the postoperative treatment of such patients.

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“…The active inflammation in the vegetation in this case could have been detected using PET scan prior to starting the antibiotic course. [13]…”

Section: Discussionmentioning

confidence: 99%

Infective endocarditis of the left main to right atrial coronary cameral fistula

Mishra

Barik

Patnaik

2016

J Cardiovasc Echography

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A 7-year-old female child presented with pyrexia of unknown origin. She had received an empirical regimen of antibiotic for possible endocarditis. Evaluation included multiple imaging supports and blood culture. She had left main coronary artery to right atrium coronary cameral fistula, restricted patent ductus arteriosus, vegetation at the right atrial exit of fistula and negative blood culture. Ongoing fever more than 2 weeks, oscillating vegetation in the echo and histopathological evidence of healing vegetation suggested definite diagnosis of infective endocarditis. She was treated successfully by surgical closure of fistula from the right atrial approach. Device closure in this case would have resulted in a large residual cul-de-sac with or without tiny residual high-velocity jets, either being a threat for future enlargement, rupture of the residual aneurysmal sac, thromboembolism, prolonged anticoagulation, and infective endocarditis.

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Clinical applications of radionuclide imaging in the evaluation and management of patients with congenital heart disease

Cited by 20 publications

References 65 publications

Practical Indication-Based Pediatric Nuclear Medicine Studies

Practical Indication-Based Pediatric Nuclear Medicine Studies

Review findings included diminished coronary flow reserve after surgery in children with congenital heart disease and inflammation

Infective endocarditis of the left main to right atrial coronary cameral fistula

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