Clinical applications of smart wearable sensors

Tao, Q. T.; Liu, Suwen; Zhang, Jingyu; Jiang, Jinling; Jin, Zhao-Hui; Huang, Yongjun; Liu, Dage; Song, Lin; Zeng, Xierong; Li, Xuemei; Tao, Guangming; Chen, Hongxiang

doi:10.1016/j.isci.2023.107485

Cited by 16 publications

(1 citation statement)

References 122 publications

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“…125 For the management of burn injuries and chronic wounds, widely employed synthetic acellular skin substitutes encompass Biobrane, Integra, Alloderm, and TransCyte. 126 Notable natural skin substitutes incorporating allogeneic cells include Dermagraft, Apligraf, and OrCel. 127,128 SWOT analysis for the development of smart advanced dressings has been represented in the Supporting Information.…”

Section: Role Of Electronic Skin In Wound Healingmentioning

confidence: 99%

Advanced Dressings for Chronic Wound Management

Mishra,

Kushare,

Gupta

et al. 2024

ACS Appl. Bio Mater.

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Wound healing, particularly for chronic wounds, presents a considerable difficulty due to differences in biochemical and cellular processes that occur in different types of wounds. Recent technological breakthroughs have notably advanced the understanding of diagnostic and therapeutic approaches to wound healing. The evolution in wound care has seen a transition from traditional textile dressings to a variety of advanced alternatives, including self-healing hydrogels, hydrofibers, foams, hydrocolloids, environment responsive dressings, growth factor-based therapy, bioengineered skin substitutes, and stem cell and gene therapy. Technological advancements, such as 3D printing and electronic skin (e-skin) therapy, contribute to the customization of wound healing. Despite these advancements, effectively managing chronic wounds remains challenging. This necessitates the development of treatments that consider performance, risk–benefit balance, and cost-effectiveness. This review discusses innovative strategies for the healing of chronic wounds. Incorporating biomarkers into advanced dressings, coupled with corresponding biosensors and drug delivery formulations, enables the theranostic approach to the treatment of chronic wounds. Furthermore, integrating advanced dressings with power sources and user interfaces like near-field communication, radio frequency identification, and Bluetooth enhances real-time monitoring and on-demand drug delivery. It also provides a thorough evaluation of the advantages, patient compliance, costs, and durability of advanced dressings, emphasizing smart formulations and their preparation methods.

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