Clinical approach to palatal necrosis in an immunocompromised patient: A dental professional’s role

Nagarajan, Nivethitha; Jayachandran, S; Jayaram, Vidya

doi:10.32677/ijcr.2020.v06.i11.006

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Possible differential diagnosis for oral mucormycosis include tertiary syphilis, Wegener’s granulomatosis, carcinoma of the palate (squamous cell carcinoma/mucoepidermoid carcinoma), midline lethal granuloma, osteomyelitis, tuberculosis, other deep fungal infections, and ulcer due to bisphosphonate therapy. [ 22 ]…”

Section: Early Diagnosis: a Critical Factor In Managing Mucormycosismentioning

confidence: 99%

Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India

Aswal

Rawat²,

Dwivedi

et al. 2022

Journal of Family Medicine and Primary Care

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With the current pandemic raging over the world, science and medicine is faced with hereto with unfought enemies or less fought opponent in the form of viruses and consequently, other biotic entities. While researchers are striving to identify and conquer the variants of COVID-19, other innocuous organisms are raising their ugly heads in the form of opportunistic fungal infections. Mucormycosis/Black Fungus is an invasive opportunistic fungal infection caused by mucorale species. It spreads through blood vessels causing thrombosis, ischemia, and necrosis. Population with pre-existing immunocompromised conditions such as Diabetes Mellitus, Malignancy, Long-term immunosuppressant therapy are more susceptible. Mucormycosis associated with Corona Virus Disease-2019 (COVID-19) proved to be catastrophic due to its high mortality rates. Rhino orbital Mucormycosis is the most common form. The primary care physician, being the first and often, (more so in developing countries) and being the only point of contact with a healthcare professional, plays a pivotal role in the diagnosis and management of this condition. The keystone to decreasing mortality is early detection and diagnosis followed by preventive measures to control progression to the brain. A multidisciplinary approach by various specialties is a prerequisite for effective diagnosis and management. Antifungal therapy, surgical debridement, and resection of the affected areas are protocols to be followed. Post-operative defects cause impairment of function, phonetics, and esthetics. Prosthetic rehabilitation of these defects has shown favorable results, especially in the aged and immunocompromised individuals.

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Section: Early Diagnosis: a Critical Factor In Managing Mucormycosismentioning

confidence: 99%

Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India

Aswal

Rawat²,

Dwivedi

et al. 2022

Journal of Family Medicine and Primary Care

View full text Add to dashboard Cite

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Mucormycosis of Maxillofacial Region in a Diabetic Patient: A Case Report, Review of Literature and an Insight Into Variuos Management Modallities.

Kasaraneni

Kumar

Reddy

et al. 2021

ijsr

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Fungi of the order Mucorales causes an invasive and potentially lethal infection known as mucormycosis. It is a devastating disease in patients with poorly controlled diabetes mellitus and immunocompromised conditions. The infection either begins in the nose and paranasal sinuses due to inhalation of fungal spores or an ulcer or extraction of teeth aids as portal of entry. The infection can also spread to orbital and intracranial structures either through direct invasion or the blood vessels. It is an aggressive infection that needs to be addressed promptly to prevent fatal consequences. We report a case of maxillary necrosis in an uncontrolled diabetic patient due to mucormycois to emphasize importance early diagnosis and treatment of this potentially fatal fungal infection. We briey review the literature of rhinocerebral mucormycosis in terms of its pathogenesis, portal of entry and predisposing factors, incidence and forms, clinical features, diagnosis, differential diagnosis and various management options.

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Clinical approach to palatal necrosis in an immunocompromised patient: A dental professional’s role

Cited by 2 publications

References 12 publications

Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India

Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India

Mucormycosis of Maxillofacial Region in a Diabetic Patient: A Case Report, Review of Literature and an Insight Into Variuos Management Modallities.

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