Clinical Aspects of Recurrent Abdominal Pain in Children

Galler, Janina R.; NEUSTEIN, STEVEN; Walker, W. Allan

doi:10.1016/s0065-3101(22)00653-3

Cited by 20 publications

(2 citation statements)

References 39 publications

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“…In our group only 7% of the pathologic findings could have been diagnosed by means other than endoscopy. At the moment, we disagree with the opinion that endoscopy should be avoided in the diagnostic workup of children with RAP (5). Histology can clarify the diagnosis in many cases, so biopsies should always be taken, even on mucosa that appears to be normal.…”

Section: Discussionmentioning

confidence: 77%

Upper Gastrointestinal Endoscopy in Recurrent Abdominal Pain of Childhood

Ashorn,

Mäki,

Ruuska

et al. 1993

J. pediatr. gastroenterol. nutr.

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SummaryOver a 2.5‐year period, 82 consecutive children complaining of recurrent abdominal pain underwent upper gastrointestinal endoscopy. Gastroscopy confirmed pathology in 48 of the children (58.5%). Four of the children, who also had undergone gastroscopy, had other diagnoses (lactose malabsorption, hydronephrosis, yersinosis), and 30 of the children (36.6%) retained the initial diagnosis of recurrent abdominal pain syndrome. Gastritis was found in 48 of the children, 18 of whom (37.5%) had positive test results for Helicobacter pylori, based on histology and/or culture. Of 16 H. pylori‐positive children tested, 12 (75%) also had an elevated concentration of IgG‐class antibodies to H. pylori in their sera. Three of the children had duodenal ulcer disease, all of whom were H. pylori positive. Esophagitis was found in eight of the children with gastritis, all of whom were found to have gastroesophageal reflux. Our data suggest that among the children with recurrent abdominal pain syndrome, organic pathology is more common than was previously thought. Altogether 22% of the children with recurrent abdominal pain syndrome were infected with H. pylori.

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Section: Discussionmentioning

confidence: 77%

Upper Gastrointestinal Endoscopy in Recurrent Abdominal Pain of Childhood

Ashorn,

Mäki,

Ruuska

et al. 1993

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

show abstract

“…Abdominal pain represents an important cause of pediatric consultation. However, it is a nonspecific symptom, and during endoscopic exploration the majority of these patients do not have any visible evidences of gastroduodenal damage (5‐7). Endoscopy is associated with some, albeit minimal, risk of morbidity and mortality and requires rather expensive installations and equipment.…”

mentioning

confidence: 99%

Sucrose Permeability in Children with Gastric Damage and Helicobacter pylori Infection

Vera,

Gotteland,

Chavez

et al. 1997

J. pediatr. gastroenterol. nutr.

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Background:Increased permeability to sucrose has been recently shown to be a good marker of gastric mucosal damage in adults.Methods:This test was evaluated in 40 children consulting for recurrent abdominal pain and the results were correlated with endoscopic and histologic findings and with the presence of H. pylori.Results:The gastric mucosa was considered endoscopically normal in 31 children; 3 had duodenitis, and 6 had mild gastritis. Abnormal endoscopic findings were associated with increased urinary sucrose excretion (MANOVA F = 7.30; p = 0.002). In the 6 children with mild gastritis, mean sucrose excretion was twice that of controls (0.060 ± 0.024 vs. 0.029 ± 0.018, respectively; p = 0.019) and significantly higher than the group with duodenitis (0.037 ± 0.013; p = 0.038). The specificity and sensitivity of sucrose permeability test for detection of gastric damage were 90.3% and 83.3%, respectively. H. pylori was detected in 62.5% of children including all patients with mild gastritis, in 2 out of 3 with duodenitis and 17 out of 31 endoscopically normal controls. No differences in sucrose excretion were observed in relation with the presence of H. pylori or histological findings in the control group.Conclusions:Urinary sucrose excretion is a good marker of mucosal gastric damage in children and may be used as a screening test in large groups of populations.

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Recurrent Abdominal Pain

Hodges¹,

Burbach²

1991

Children in Pain

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Objectives To test whether children with recurrent abdominal pain (RAP) exhibit subliminal (nonconscious) and supraliminal (conscious) attentional biases to pain-related words, and to determine correlates of these biases. Previous research indicates that individuals attend to disorder-relevant threat words, and in this study, attentional biases to disorder-relevant threat (pain), alternative threat (social threat), and neutral words were compared. Methods Participants were 59 children with RAP who completed a computer-based attentional bias task. Participants and their parents also completed questionnaires measuring pain, somatic complaints, anxiety/ depression, and body vigilance. Results Children with RAP showed attentional biases toward subliminal pain-related words and attentional biases away from supraliminal painrelated words. Participants' attentional biases to social threat-related words were marginally significant and also reflected subliminal attention and supraliminal avoidance. Attentional biases were related to parent and child reports of pain, body vigilance, and anxiety/ depression. Conclusions Children with RAP show nonconscious attention to and conscious avoidance of threat-related words. Their attentional biases relate to individual differences in symptom severity. Implications for models of pediatric pain and future studies are discussed.

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Clinical Aspects of Recurrent Abdominal Pain in Children

Cited by 20 publications

References 39 publications

Upper Gastrointestinal Endoscopy in Recurrent Abdominal Pain of Childhood

Upper Gastrointestinal Endoscopy in Recurrent Abdominal Pain of Childhood

Sucrose Permeability in Children with Gastric Damage and Helicobacter pylori Infection

Recurrent Abdominal Pain

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