Clinical benefit of hydroxyapatite-coated pins compared with stainless steel pins in external fixation at the wrist: A randomised prospective study

Biomimetic Hydroxyapatite Coated Titanium Screws Demonstrate Rapid Implant Stabilization and Safe Removal <i>In-Vivo</i>

“…"Biologically, the early phase (days) after implantation of an implantable device is considered to be critical to the long-term implant stability" [40]. The HA coating appears to improve early implant stabilization and therefore, ensures that initial implant placement is maintained [41] [42]. After implantation the HA coating was modulating the early biological response of the bone and the surrounding tissue to the screw implant.…”

Treatment of Gustilo grade III tibial fractures with unreamed intramedullary nailing versus external fixator: A meta-analysis

“…Intramedullary nailing allows earlier extremity weight loading and less stress shielding, [2] which can result in better fracture union. External fixation also is popular because of its easy application and economy, while pin site complications such as infection may be major hazards to consider and to prevent [3]. External fixation is usually recommended more for severe open fractures, and it is more successful in superficial bones such as the tibia [4].…”

Advanced bioactive and biodegradable ceramic biomaterials

“…models, including rabbit (Patel et al , 2002;Tamai et al , 2002), pig (Chu et al , 2002;Ramselaar et al , 1991) and dog (Kikuchi et al , 2001). In human patients, the use of hydroxyapatite-coated pins for external fi xation of unstable wrist fractures indicated potentially superior clinical performance; however, the difference in healing outcomes in this study was not statistically signifi cant (Pieske et al , 2010). In addition to coatings, clinical applications of hydroxyapatite include sintered macroporous granules and cements in nonload-bearing applications.…”