Clinical callosum syndrome in a case of multiple sclerosis

Moroni, Christine; Belin, Cathérine; Haguenau, M; Salama, J.

doi:10.1046/j.1351-5101.2003.00734.x

Cited by 10 publications

(5 citation statements)

References 13 publications

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“…Tasks which evaluate transfer of auditive, motor and somesthesic information also shown a deficit in interhemispheric transfer [22][23][24]. Some rare cases of MS patients presenting a real syndrome of callosal disconnection were also reported [25]. Ipsilateral Silent Period (ISP) paradigm revealed that transcallosal conduction is significantly slower in MS patients [26].…”

Section: Introductionmentioning

confidence: 99%

Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis

Lenne

Blanc

Nandrino

et al. 2013

Behavioural Neurology

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The disturbance of cortical communication has been hypothesized as an important factor in the appearance of cognitive impairment in (MS). Cortical communication is quantified here in control subjects and patients with relapsing-remitting multiple sclerosis (RRMS) on the basis of mean coherence in the δ, θ, α, β and γ bands and using mutual information computed between pairs of bipolar EEG signals recorded during resting condition. Each patient received also a cognitive assessment using a battery of neuropsychological tests specific to cognitive deficits in MS.No difference was observed for the coherence indices whereas inter-hemispheric and right hemisphere mutual information is significantly lower in patients with MS than in control subjects. Moreover, inter-hemispheric mutual information decrease significantly with illness duration and right mutual information differentiate cognitively deficient and non-deficient patients.Mutual information allows to quantify the cortical communication in patients with RRMS and is related to clinical characteristics.Cortical communication quantified in a resting state might be a potential marker for the neurological damage induced by RRMS.

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Section: Introductionmentioning

confidence: 99%

Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis

Lenne

Blanc

Nandrino

et al. 2013

Behavioural Neurology

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“…Diffusion tensor tractography (DTT), derived from diffusion tensor imaging (DTI), allows for threedimensional visualization of CC fibers [12][13][14][15]. Therefore, DTT has been used for the assessment of disruptions of CC fibers in patients with brain injury, including diffuse axonal injury (DAI) and stroke [16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Unusual compensatory neural connections following disruption of corpus callosum fibers in a patient with corpus callosum hemorrhage

Jang

Yeo

Lee

2013

International Journal of Neuroscience

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“…Here we report a single case study of a 47-year-old woman, with 35-year history of multiple sclerosis (MS) who presented with alien hand signs. Alien hand has been described in MS only occasionally, generally associated with callosal involvement [7, 8]. Even though inflammatory demyelination and axon damage in the corpus callosum are prominent features of MS, clinical manifestations of alien hand or other signs of callosal disconnection, such as callosal apraxia or unilateral agraphia, have been scarcely reported.…”

Section: Introductionmentioning

confidence: 99%

Intermittent Alien Hand Syndrome and Callosal Apraxia in Multiple Sclerosis: Implications for Interhemispheric Communication

Lunardelli

Sartori

Mengotti

et al. 2014

Behavioural Neurology

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We report a case of a 47-year-old woman with 35-year history of multiple sclerosis, who showed alien hand signs, a rare behavioural disorder that involves unilateral goal-directed movements that are contrary to the individual's intention. Alien hand syndrome has been described in multiple sclerosis (MS) only occasionally and is generally suggestive of callosal disconnection. The patient presented also with bilateral limb apraxia and left hand agraphia, raising the possibility of cortical dysfunction or disconnection, in addition to corpus callosum and white matter involvement. Her specific pattern of symptoms supports the role of the corpus callosum in interhemispheric communication for complex as well as fine motor activities and may indicate that it can serve as both an inhibitory and excitatory function depending on task demands.

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Clinical callosum syndrome in a case of multiple sclerosis

Cited by 10 publications

References 13 publications

Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis

Decrease of Mutual Information in Brain Electrical Activity of Patients with Relapsing-Remitting Multiple Sclerosis

Unusual compensatory neural connections following disruption of corpus callosum fibers in a patient with corpus callosum hemorrhage

Intermittent Alien Hand Syndrome and Callosal Apraxia in Multiple Sclerosis: Implications for Interhemispheric Communication

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