Clinical case of treatment of patient with aHUS in obstetrical practice. Experience of anesthesiology and resuscitation department

Abstract

Atypical hemolytic-uremic syndrome (aHUS), a variant of thrombotic micro angiopathy (TMA), is a life-threatening disease that leads to multiple organ damage with the high rate of maternal mortality or the disability of surviving. Our experience of the clinical course of the disease, launched after delivery, features of multiple organ failure, intensive care unit monitoring and treatment is presented in the article. We suggest, timely diagnosis and early specific anticomplementary therapy with complex and escalation treatment of multiple organ failure, which can be realized only in large multidisciplinary medical centers, can contribute to the improvement of outcomes.

Controversial Issues in the Management of Patients with HELLP Syndrome

“…Женщин с HELLP-синдромом, текущей ТМА должны вести совместно акушер-гинеколог и анестезиолог-реаниматолог с соответствующим клиническим опытом и современными знаниями, а также смежные специалисты (кардиолог, гематолог, нефролог) в стационаре III уровня [16][17][18][19].…”