2022
DOI: 10.1186/s13741-021-00234-z
|View full text |Cite
|
Sign up to set email alerts
|

Clinical characteristics and allergen detection of perioperative anaphylaxis: a 12-year retrospective analysis from an anesthesia clinic in China

Abstract: Background Anaphylaxis during anesthesia is a rare but often a potentially life-threatening event for patients. Identifying culprit agents responsible for anaphylaxis is of great important for avoiding potential re-exposure to allergens, but it poses great challenge for anesthetists. This retrospective study aimed to analyze the culprits of patients with a history of perioperative anaphylaxis referred to an anesthesia allergy clinic in China, and to evaluate the role of allergy diagnostic tests… Show more

Help me understand this report
View preprint versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
7
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 6 publications
(7 citation statements)
references
References 40 publications
0
7
0
Order By: Relevance
“…No reports of local anesthesia or latexinduced allergy were found. 12 The most common symptoms noticed were hypotension (46%), bronchospasm (18%), tachycardia (9.8%), oxygen desaturation (4.7%), bradycardia (3%), and reduced/absent capnography trace (2.3%). All patients indicated hypotension.…”
Section: Resultsmentioning
confidence: 99%
“…No reports of local anesthesia or latexinduced allergy were found. 12 The most common symptoms noticed were hypotension (46%), bronchospasm (18%), tachycardia (9.8%), oxygen desaturation (4.7%), bradycardia (3%), and reduced/absent capnography trace (2.3%). All patients indicated hypotension.…”
Section: Resultsmentioning
confidence: 99%
“…They ranked second in the list of causative agents among total SRsAs, pediatric SRsAs, and fatal SRsAs. LAs are typical triggers of anaphylaxis in dentistry practice [ 32 ], though the risk of true IgE-mediated allergy was shown to be lower than 1% [ 33 , 34 , 35 , 36 , 37 ]. Amide local anesthetics are less involved in hypersensitivity reactions compared with ether local anesthetics, and among the amides, lidocaine is known to be the most associated with severe allergic reactions.…”
Section: Discussionmentioning
confidence: 99%
“…Table 1 provides a list of drugs concentrations used in BAT. 8 14 15 For each tube, basophil activation is induced by adding 50 µL of the patient’s whole blood sample, 50 µL of the corresponding stimulator (with the stimulation buffer serving as the patient’s background control and FcεRI antibody as the stimulus quality control) and 100 µL of the stimulation buffer.…”
Section: Methods and Analysismentioning
confidence: 99%
“…Conventional diagnostic methods, such as skin testing (ST) and basophil activation testing (BAT), often fall short in their diagnostic capacity, leaving many POA cases unresolved. 8 This diagnostic gap can significantly hamper the anaesthesiologist’s ability to select appropriate drugs for anaesthesia, which may affect surgical management.…”
Section: Introductionmentioning
confidence: 99%