Clinical Characteristics and Long-Term Outcomes of Patients Undergoing Combined Heart-Kidney Transplantation: A Single-Center Experience

López-Sainz, Ángela; Barge‐Caballero, Eduardo; Paniagua‐Martin, María J.; Rivas, Raquel Marzoa; Sánchez-Fernández, Gabriel; Arias, Laura; García-Vieites, María; Alonso-Hernández, Ángel; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María G.

doi:10.1016/j.transproceed.2014.11.009

Cited by 13 publications

(4 citation statements)

References 8 publications

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“…8 In our analysis of 1507 SKHT from the UNOS/OPTN database, we demonstrate excellent overall patient and graft survival. The median survival of 12.4 years in SKHT recipients and 11.3 years in HTA recipients is consistent with previous single-center 6,10,11 and large database studies. [2][3][4] J o u r n a l P r e -p r o o f…”

Section: Discussionsupporting

confidence: 89%

Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States

Agarwal

Patel

Agrawal

et al. 2021

Kidney International Reports

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Discussionsupporting

confidence: 89%

Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States

Agarwal

Patel

Agrawal

et al. 2021

Kidney International Reports

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“…Studies regarding long-term follow-up of combined heart-kidney transplant reported the occurrence of de-novo malignancies as well, mainly represented by skin cancers and lymphoproliferative diseases but also from solid cancers in up to 25% of cases, even though small samples are available [19,22,23].…”

Section: Discussionmentioning

confidence: 99%

Advanced native-kidney carcinoma in a heart- and kidney-transplanted patient: a case report

et al. 2018

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Malignancies are one of the leading causes of death in long-term surviving transplant recipients. Dose and prolonged durations of immunosuppressive regimens are considered the main cause, through a direct oncogenic effect and a renowned interaction on physiological anti-viral and anti-oncogenic immune response. Specific neoplasms are known to occur with different frequencies according to the transplanted organ. As a consequence, imaging screenings have been implemented in many graft surveillance programs, although a wide consensus on the timing and modality has not been concurred. There are little data available in the literature regarding incidence of de-novo malignancies in multi-organ recipients. We report the case of a 66-year-old man who developed a renal mass 10 years after a combined heart-kidney transplant.

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“…A total of 781 articles were identified based on the literature search criteria and 15 eligible papers were included in qualitative synthesis and meta-analysis [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24], including 376 patients who underwent the procedure from 1996 to 2019. All articles were single-center retrospective studies from 15 different transplantation centers in Austria, Belgium, the United States of America, the United Kingdom, Germany, Taiwan, Italy, New Zealand, Argentina, Spain, France, and Brazil.…”

Section: Characteristics Of the Selected Literaturementioning

confidence: 99%

Simultaneous Heart and Kidney Transplantation: A Systematic Review and Proportional Meta-Analysis of Its Characteristics and Long-Term Variables

Sampaio,

Faleiro,

Vieira

et al. 2024

Transpl Int

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Patients with end-stage heart disease who undergo a heart transplant frequently have simultaneous kidney insufficiency, therefore simultaneous heart and kidney transplantation is an option and it is necessary to understand its characteristics and long-term variables. The recipient characteristics and operative and long-term variables were assessed in a meta-analysis. A total of 781 studies were screened, and 33 were thoroughly reviewed. 15 retrospective cohort studies and 376 patients were included. The recipient’s mean age was 51.1 years (95% CI 48.52–53.67) and 84% (95% CI 80–87) were male. 71% (95% CI 59–83) of the recipients were dialysis dependent. The most common indication was ischemic cardiomyopathy [47% (95% CI 41–53)] and cardiorenal syndrome [22% (95% CI 9–35)]. Also, 33% (95% CI 20–46) of the patients presented with delayed graft function. During the mean follow-up period of 67.49 months (95% CI 45.64–89.33), simultaneous rejection episodes of both organ allografts were described in 5 cases only. Overall survival was 95% (95% CI 88–100) at 30 days, 81% (95% CI 76–86) at 1 year, 79% (95% CI 71–87) at 3, and 71% (95% CI 59–83) at 5 years. Simultaneous heart and kidney transplantation is an important option for concurrent cardiac and renal dysfunction and has acceptable rejection and survival rates.

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Clinical Characteristics and Long-Term Outcomes of Patients Undergoing Combined Heart-Kidney Transplantation: A Single-Center Experience

Cited by 13 publications

References 8 publications

Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States

Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States

Advanced native-kidney carcinoma in a heart- and kidney-transplanted patient: a case report

Simultaneous Heart and Kidney Transplantation: A Systematic Review and Proportional Meta-Analysis of Its Characteristics and Long-Term Variables

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