Clinical Characteristics and Outcome of Post-Infectious Glomerulonephritis in Children in Southern India: A Prospective Study

Gunasekaran, Kuralvanan; Krishnamurthy, Sriram; Mahadevan, Subramanian; Harish, Belgode Narasimha; Kumar, Ajith Prabhu

doi:10.1007/s12098-015-1752-0

Cited by 41 publications

(57 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Rajajee et al study 13 [12][13][14]5 In the present study, at the time of presentation 82.5% of patients had low levels of serum C3 suggesting post infectious glomerulonephritis. Normal C3 at the time of onset of disease was present in 17.5% of patients.…”

supporting

confidence: 45%

“…5 In our study only 2.9% developed hypertensive encephalopathy and Congestive cardiac failure was present in 4.9%.…”

contrasting

confidence: 41%

“…In a recent study from South India (2015), the mean age was 6.8 years with 78.5% of subjects being above 5-year-old. 5 The immature immune response in very young children has been attributed as the cause for rarity of APSGN in this age group. 7,8 In the present study the age group ranged from 2 to 12 years and the peak age group was 6 to 8 years i.e.…”

Section: Discussionmentioning

confidence: 99%

“…ASO titre more than 200IU/ml was considered as evidence for recent streptococcal infection. 5 Serum complement 3 (C3) levels were measured by immunoturbidimetric method. APSGN was diagnosed based on the following criteria.…”

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Clinical profile and outcome of acute nephritic syndrome in children from a tertiary care centre in south India: a descriptive study

Valiyat

Valoor

2017

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: Acute nephritic syndrome (ANS) is major cause of morbidity in developing countries. This study is an attempt to evaluate the clinical characteristics, complications and outcome of acute nephritic syndrome.Methods:This hospital based descriptive study was conducted at a tertiary care hospital in Kerala, South India. 103 children with ANS were analysed. Detailed clinical examination and relevant laboratory investigations were done. These children were followed up for 1 year.Results: Out of 103 patients studied 64% were male and 36% were female. The peak age group was 6 to 8 years. Skin infection was the most common predisposing condition (68.9%). Hypertension was present in 60.1% of patients. 26.2% of patients developed complications. Of these Acute renal failures was the most commonly encountered complication (18.4%). Proteinuria (87.4%) and microscopic hematuria (80.6%) were the most consistent features. 82.5 % patients had low C3 at the time of diagnosis. Majority of patients with low C3 level had positive ASO titre. (p = 0.014). At 3month follow up C3 became normal in 95.2% of patients. At 3 months’ majority of patients with normal C3 had incomplete recovery. (p = 0.010). At the end of 12m, microscopic heamaturia was present in 4 patients, persistent hypertension in 2 patients, 11 patients had proteinuria. These patients are kept under long term follow up.Conclusions:Complications and morbidity is significantly high during the acute phase in ANS. This study highlights the need for long term follow up of these patients.

show abstract

supporting

confidence: 45%

“…5 In our study only 2.9% developed hypertensive encephalopathy and Congestive cardiac failure was present in 4.9%.…”

contrasting

confidence: 41%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Clinical profile and outcome of acute nephritic syndrome in children from a tertiary care centre in south India: a descriptive study

Valiyat

Valoor

2017

Int J Contemp Pediatr

View full text Add to dashboard Cite

show abstract

“…(14) Acute Poststreptococcal Glomerulonephritis (PSGN): (a) Features of ANS +; (b) Evidence of recent streptococcal infection i.e., pharyngitis, pyoderma or serological evidences (raised ASO); (c) With low serum C3 levels with normalisation at 8 weeks.…”

Section: Methodsmentioning

confidence: 99%

Clinical Profile and Short-Term Outcome of Acute Nephritic Syndrome in Children

Kamalakarababu¹,

Sam²,

Varghese³

2017

jemds

View full text Add to dashboard Cite

show abstract

Acute Kidney Injury in the Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment

Parameswaran

Jha

2018

Core Concepts in Acute Kidney Injury

View full text Add to dashboard Cite

Clinical Characteristics and Outcome of Post-Infectious Glomerulonephritis in Children in Southern India: A Prospective Study

Abstract: PIGN (including PSGN) remains a significant contributor to morbidity in children with ANS. The study is notable for high incidence of hypertensive emergency and AKI, that often required intensive care management.

Cited by 41 publications

References 19 publications

Clinical profile and outcome of acute nephritic syndrome in children from a tertiary care centre in south India: a descriptive study

Clinical profile and outcome of acute nephritic syndrome in children from a tertiary care centre in south India: a descriptive study

Clinical Profile and Short-Term Outcome of Acute Nephritic Syndrome in Children

Acute Kidney Injury in the Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment

Contact Info

Product

Resources

About