Clinical characteristics and outcomes of Takayasu's arteritis: analysis of 108 patients using standardized criteria for diagnosis, activity assessment, and angiographic classification

Park, M. C.; Lee, S. W.; Park, Yong Bum; Chung, Namsik; Lee, S. K.

doi:10.1080/03009740510026526

Cited by 240 publications

(157 citation statements)

References 24 publications

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“…В 2017 г. на момент постановки диагноза СОЭ составляла 28 мм/ч, СРБ -28,9 мг/л. Повышение СОЭ отмечается у подавляю-щего большинства больных [12]. Необходимо отметить, что отклонение от нормы уровней маркеров острофа-зового воспаления далеко не всегда отражает сниже-ние или повышение активности болезни и имеет ограниченное значение для принятия решений о кор-рекции терапии [13].…”

Section: клиническое наблюдениеunclassified

Systemic Vasculitis With Lesion of Large Vessels as a Cause of Art Erial Hypert Ension in a Patient of Young Age

et al. 2018

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Objective:to analyze and present a clinical case of late diagnosis of Takayasu’s arteritis in a young female patient with long-term arterial hypertension.Materials and methods.The female patient G., born in 1989, had noted elevated arterial pressure (AP) of 150/90 mm Hg since she was 14. At 21 the following diagnosis was stated: Fibro-muscular dysplasia, stenosis of the left renal artery. Stenosis of the celiac trunk. Aneurisms of the branches of the superior mesenteric artery; prosthesis of the left renal artery was performed. Since the beginning of 2016, the patient has noted elevated AP of 200/110 mm Hg despite continuing hypotensive therapy. Diagnosis of Nonspecific aortoarteritis was proposed in May of 2017. Methylprednisolone therapy was administered: 250 mg No. 2 intravenously, Prednisolone: 25 mg a day orally. Due to signs of decreased blood flow to the left kidney, in August of 2017 extracorporeal repeat prosthesis of the left renal artery, bypass of the right middle renal artery with reversed autovein were performed.Results.During examination in October of 2017, the patient complained of weakness, frequent elevated AP of 200/110 mm Hg. In blood test: hemoglobin 106 g/l, erythrocyte sedimentation rate 38 mm/h, C-reactive protein 25 mg/l. A heterozygous mutation in the methylenetetrahydropholate reductase, a heterozygous mutation in the factor V gene (G1691A) were identified. Homocysteine level was normal, infection and oncological pathology were excluded. The following diagnosis was made: Takayasu»s arteritis type IV affecting the aorta and its branches, moderate activity. Occlusion of the celiac trunk. Aneurisms of the branches of the superior mesenteric artery. Critical stenosis of the left renal artery. Thrombosis of the aorto-renal prosthesis. Hypoplasia of the left kidney. Prednisolone 50 mg a day, metoprolol 50 mg a day, valsartan 160 mg a day, acetylsalicylic acid 100 mg a day were prescribed.Conclusion.The presented clinical observation shows the importance of comprehensive examination of young patients complaining of elevated AP for many years. Due to untimely diagnosis and absence of pathogenetic therapy, the patient suffered negative consequences of surgical treatment.

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Section: клиническое наблюдениеunclassified

Systemic Vasculitis With Lesion of Large Vessels as a Cause of Art Erial Hypert Ension in a Patient of Young Age

et al. 2018

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“…In the Cleveland cohort (Maksimowicz-McKinnon et al, 2007), only 20% of patients persisted on remission with <10 mg prednisolone for 6 months. It is therefore common the need of an additional immunosuppressive agent to induce or maintain remission in large cohorts (Kerr et al, 1994;Vanoli et al, 2005;Park et al, 2005). Granulomatous inflammation is one of the key histopathological features of large vessel vasculitides.…”

Section: Large Vessel Vasculitidesmentioning

confidence: 99%

The Role of Biological Therapies in the Management of Systemic Vasculitis

Vela¹,

Andrés²

2011

Advances in the Diagnosis and Treatment of Vasculitis

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“…По данным Phillip и соавт., общий пока-затель 10-летней выживаемости составляет около 90% [6], а по версии Park и соавт., по-казатели 5-и 10-летней выживаемости со-ставили 69 и 36% соответственно [7]. В то же время Schmidt и соавт.…”

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“…Такие факторы, как пол, артериальная гипертензия, наличие осложнений и их количество, прогрессивное течение заболевания, оказали влияние на выживаемость пациентов с неспецифичес-ким аортоартериитом, что совпадает с дан-ными авторов других [2, 3,7,11,12].…”

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“…продемонстрировали, что у пациентов, страдающих неспецифи-ческим аортоартериитом и имеющих 3-ю стадию заболевания, хирургическая кор-рекция повышала выживаемость, а частота осложнений, ассоциированных с хирурги-ческими вмешательствами, повышались у пациентов с 1-й стадией заболевания [7].…”

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Factors influencing survival of patients suffering from nonspecific aortoarteritis

et al. 2017

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Clinical characteristics and outcomes of Takayasu's arteritis: analysis of 108 patients using standardized criteria for diagnosis, activity assessment, and angiographic classification

Abstract: These findings could provide useful information on the clinical features, angiographic findings, and outcomes in TA, particularly on the assessment of patients at risk of a poor outcome.

Cited by 240 publications

References 24 publications

Systemic Vasculitis With Lesion of Large Vessels as a Cause of Art Erial Hypert Ension in a Patient of Young Age

Systemic Vasculitis With Lesion of Large Vessels as a Cause of Art Erial Hypert Ension in a Patient of Young Age

The Role of Biological Therapies in the Management of Systemic Vasculitis

Factors influencing survival of patients suffering from nonspecific aortoarteritis

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