Clinical characteristics and outcomes of infective endocarditis: impact of haemodialysis status, especially vascular access infection on short-term mortality

Kwon, Seong Soon; Park, Se Yoon; Bang, Duk Won; Hyon, Min-Su; Lee, Seong Soo; Yun, Sangchul; Song, Dan; Park, Byoung-Won

doi:10.1080/23744235.2021.1916587

Cited by 2 publications

(4 citation statements)

References 25 publications

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“…In the present study, the mean ages of HD and non-HD patients were not significantly different, which is in line with studies by Bentata et al, Kwon et al, Hsiao et al, and Zhang et al, who have not noted any statistically significant age difference between the groups [ 20 , 23 , 24 , 26 ]. In contrast, Stahl et al and Bhatia et al reported significantly lower mean ages in the hemodialysis group [ 8 , 25 ].…”

Section: Discussionsupporting

confidence: 92%

“…In our study, valve surgeries were performed on 52.94% of the HD patients, similar to the non-HD group (57.14%). In line with several previous investigations by Durante-Mangoni et al, Hsiao et al, and Kwon et al, there was no significant difference in the surgical requirements between the studied groups [ 24 , 26 , 36 ]. However, other studies by Stahl et al, Pericas et al, and Zhang et al reported cardiac surgery being performed in a significantly lower number of HD patients than in non-HD patients [ 19 , 20 , 25 ].…”

Section: Discussionsupporting

confidence: 92%

“…Consistent with most prior studies, in-hospital mortality was significantly higher in the HD group than in the non-HD group [ 5 , 19 , 20 , 24 , 27 ]. However, Stahl et al and Durante-Mangoni et al reported no significant differences between the two groups [ 25 , 36 ].…”

Section: Discussionsupporting

confidence: 89%

“…Studies by Kwon et al, Zhang et al, and Durante-Mangoni et al could not demonstrate any significant differences in terms of vegetation of size and location between HD and non-HD patients [ 20 , 24 , 36 ].…”

Section: Discussionmentioning

confidence: 90%

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Comparative analysis of infective endocarditis in hemodialysis versus non-hemodialysis patients in Iran: implications for clinical practice and future research

Zolfaghari,

Peighambari,

Kohansal

et al. 2024

BMC Cardiovasc Disord

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Background In hemodialysis (HD) patients, there is a larger frequency of mortality and morbidity associated with infective endocarditis (IE) as opposed to the general population. Despite the increased burden of IE in the HD population, optimal strategies for prevention and management still need to be clarified. Elucidating the distinguishing features and outcomes of IE in HD patients is crucial to guide clinical decision-making and improve prognosis in this high-risk group. However, the details of IE characteristics, specifically in HD patients in the Middle East, are limited. Objective To compare the clinical characteristics and short-term outcomes of IE between HD and non-HD patients. Methods A retrospective analysis was carried out on 139 patients with infective endocarditis who were referred to a tertiary cardiovascular center in Iran from 2006 to 2018. The participants were split into HD (n = 34) and non-HD (n = 105) groups. Data pertaining to demographic characteristics, comorbidities, microbiological findings, occurrence of complications, therapeutic interventions, and mortality rates during hospital stay were gathered. Results Diabetes, hypertension, and congestive heart failure were observed more frequently in HD patients. HD patients were more likely than non-HD patients to have involvement of the right valve (41.2% vs. 20.9%), larger vegetation, and extracardiac emboli. In-hospital mortality was 41.2% for HD patients versus 14.3% for non-HD patients. Mortality remained high after valve surgery in HD patients (38.2% vs. 10.5% in non-HD). Conclusion HD patients exhibited a distinct clinical profile of IE with worse short-term outcomes, including higher mortality.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 90%

See 2 more Smart Citations

Comparative analysis of infective endocarditis in hemodialysis versus non-hemodialysis patients in Iran: implications for clinical practice and future research

Zolfaghari,

Peighambari,

Kohansal

et al. 2024

BMC Cardiovasc Disord

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Infective Endocarditis in Patients with End-Stage Renal Disease on Dialysis: Epidemiology, Risk Factors, Diagnostic Challenges, and Management Approaches

Issa,

Chaaban,

Salahie

et al. 2024

Healthcare

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Infective endocarditis (IE) poses a significant clinical challenge, especially among patients with end-stage renal disease (ESRD) undergoing dialysis, and is associated with high morbidity and mortality rates. This review provides a contemporary discussion of the epidemiology, risk factors, diagnostic challenges, and management strategies for IE among ESRD patients, including a literature review of recent studies focused on this vulnerable population. The review highlights the multifactorial nature of IE risk in ESRD patients, emphasizing the roles of vascular access type, dialysis modality, and comorbid conditions. It also explores the diagnostic utility of different imaging modalities and the importance of a multidisciplinary approach in managing IE, including both medical and surgical interventions. The insights from this review aim to contribute to the improvement of patient outcomes through early recognition, appropriate antimicrobial therapy, and timely surgical intervention when necessary.

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Clinical characteristics and outcomes of infective endocarditis: impact of haemodialysis status, especially vascular access infection on short-term mortality

Cited by 2 publications

References 25 publications

Comparative analysis of infective endocarditis in hemodialysis versus non-hemodialysis patients in Iran: implications for clinical practice and future research

Comparative analysis of infective endocarditis in hemodialysis versus non-hemodialysis patients in Iran: implications for clinical practice and future research

Infective Endocarditis in Patients with End-Stage Renal Disease on Dialysis: Epidemiology, Risk Factors, Diagnostic Challenges, and Management Approaches

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