Clinical characteristics and outcomes of intratemporal facial nerve neurofibromas

Liu, Liang; Xiang, Dongdong; Li, Yefeng; Sun, Jiayu

doi:10.1016/j.amjoto.2015.01.001

Cited by 6 publications

(7 citation statements)

References 17 publications

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“…Auditory symptoms were the second most common symptoms and included otalgia with the onset of facial palsy, hearing loss, and pulsatile tinnitus. 1,3,5,7,10 In our case, patient presented with progressive facial palsy with otalgia accompanied the palsy at the onset. Facial nerve tumors which could either grow along the facial nerve and presenting with facial palsy or invaded the middle ear directly and presenting with auditory symptoms like hearing loss and pulsatile tinnitus.…”

Section: Discussionmentioning

confidence: 60%

“…1 In Liu L et al study, multi-segment involvement of the facial nerve was found in 50% of the cases (5 of 10 cases with FNN) and usually containing geniculate ganglion or tympanic segment. 3 In Dai et al report, two or more segments of facial nerve were affected in 54% of cases (6 of 11 cases with FNN). 5 Yamamoto el at report, two or more segments affected in all cases (2 of 2 cases).…”

Section: Discussionmentioning

confidence: 93%

“…6 As schwannomas and neurofibromas share common imaging characteristics including multi-segmental and multifocal occurrence, the diagnosis could not be made based on clinical and imaging findings alone. 3,5,7 The differential diagnosis between the two tumors dependent on pathological examination. Schwannomas are composed exclusively of neoplastic cells that simulate the appearance of differentiated Schwann cells, while neurofibromas display a mixture of cell types, including Schwann cells, perineurial cells, and endoneurial fibroblasts.…”

Section: Discussionmentioning

confidence: 99%

“…2 FNN are rare benign tumors, which originate along the facial nerve and are most commonly located in the parotid gland, and FNN in temporal bone are rarely reported. 3 The majority of neurofibromas occur sporadically, although about 10% ultimately prove to be associated with neurofibromatosis type1 (NF1). 4 We described the extremely rare occurrence of a histologically verified neurofibroma primarily arising in the mastoid segment of the facial nerve in a patient not fulfilling diagnostic criteria for neurofibromatosis.…”

Section: Introductionmentioning

confidence: 99%

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Intratemporal facial nerve neurofibroma: a case report and review of literature

Vijayendra¹,

Yousef²,

Vijayendra³

et al. 2023

Int J Otorhinolaryngol Head Neck Surg

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Facial nerve neurofibromas (FNN) are a rare benign tumor of facial nerve can arise from anywhere along the course of the facial nerve from the cerebellopontine angle (CPA) to the extracranial branches within the parotid. They are most commonly located in the parotid gland, and FNN in temporal bone are rarely reported. Intratemporal facial neurofibroma arise from facial nerve in internal auditory canal or in Fallopian canal. It usually manifests as progressive facial palsy, but also can present as sudden or repetitive facial palsy mimicking Bell’s palsy. We reported a case of intratemporal facial neurofibroma arising mainly from mastoid segment in 17-year-old female who presented with progressive facial palsy for 3 years. We briefly reviewed previous cases of intratemporal facial neurofibroma reported in the literature to provide a comprehensive understanding of this rare entity.

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Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intratemporal facial nerve neurofibroma: a case report and review of literature

Vijayendra¹,

Yousef²,

Vijayendra³

et al. 2023

Int J Otorhinolaryngol Head Neck Surg

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“…They reported that complete tumor removal and nerve grafting had better outcomes for the facial nerve compared with complete tumor removal with nerve integrity preserved. 17 Radiosurgery is a safe therapeutic alternative for patients with small to medium-size facial schwannomas. 18 It may be preferred as a first-line treatment when the tumor is smaller or as a salvage treatment for residual/recurrent tumors that remain or progress after resection.…”

Section: Discussionmentioning

confidence: 99%

Large Intratemporal Facial Nerve Schwannoma without Facial Palsy: Surgical Strategy of Tumor Removal and Functional Reconstruction

Yetışer

2018

J Neurol Surg A Cent Eur Neurosurg

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Conservative treatment with sparing of the nerve is considered in patients with small tumors. Excision of a large facial schwannoma with immediate hypoglossal nerve grafting as a primary procedure can provide satisfactory facial nerve function. One of the disadvantages of performing anastomosis is that there is not enough neural tissue just before the bifurcation of the main stump to provide neural suturing without tension because middle fossa extension of the facial schwannoma frequently involves the main facial nerve at the stylomastoid foramen. Reanimation should be processed with extensive backward mobilization of the hypoglossal nerve.

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