2020
DOI: 10.21203/rs.3.rs-115006/v1
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Clinical characteristics and prognosis of castleman disease patients in a Chinese hospital: paraneoplastic pemphigus is an independent risk factor

Abstract: Background Castleman disease (CD) is a rare lymphoproliferative disorder that has had limited clinical research. This study aims to detect the clinical manifestations, pathological features, and prognostic factors of this disease.Methods This study retrospectively analyzed the information of 54 patients with CD hospitalized in a single centre. A Cox regression model was employed to perform univariate analysis and multivariate analysis in order to identify independent prognostic factors for survival.Results Bas… Show more

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“…As demonstrated in this small series, early clinical suspicion, extensive imaging to investigate for often clinically silent malignancy, intensive multidisciplinary care, awareness for and management of BO, if present, resulted in impressive long‐term survival when compared with recent data of less than 50% survival at 6 years 12 …”
Section: Discussionmentioning
confidence: 66%
“…As demonstrated in this small series, early clinical suspicion, extensive imaging to investigate for often clinically silent malignancy, intensive multidisciplinary care, awareness for and management of BO, if present, resulted in impressive long‐term survival when compared with recent data of less than 50% survival at 6 years 12 …”
Section: Discussionmentioning
confidence: 66%