2023
DOI: 10.2147/ijgm.s401803
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Clinical Characteristics and Risk Factors of Neonatal Hypoxic-Ischaemic Encephalopathy and Its Associated Neurodevelopmental Outcomes During the First Two Years of Life: A Retrospective Study in Saudi Arabia

Abstract: Objective This study aimed to determine the clinical characteristics and factors associated with neonatal hypoxic-ischaemic encephalopathy (HIE) and its neurodevelopmental outcomes. Methods We conducted retrospective case-control research to investigate the clinical and labour-related risk factors for HIE. In addition, a single-centre cohort study was conducted on infants with HIE to describe their neurodevelopment from birth to 24 months. For this investigation, cases … Show more

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Cited by 2 publications
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“…It is defined as a neurological syndrome characterized by impaired respiratory function, diminished reflexes, low muscle tone, a reduced heart rate, and seizures in newborns following birth. HIE results from a combination of reduced oxygen delivery (hypoxia) and diminished blood flow (ischemia) to the brain (1)(2)(3). This condition is categorized into mild, moderate, and severe forms, reflecting its clinical severity (4).…”
Section: Introductionmentioning
confidence: 99%
“…It is defined as a neurological syndrome characterized by impaired respiratory function, diminished reflexes, low muscle tone, a reduced heart rate, and seizures in newborns following birth. HIE results from a combination of reduced oxygen delivery (hypoxia) and diminished blood flow (ischemia) to the brain (1)(2)(3). This condition is categorized into mild, moderate, and severe forms, reflecting its clinical severity (4).…”
Section: Introductionmentioning
confidence: 99%
“…Hypoxic-ischemic encephalopathy (HIE) is a serious condition that affects newborns who experience oxygen deprivation and reduced blood flow to the brain which can cause brain damage, seizures, developmental delays, and cerebral palsy [20,21]. However, the risk factors and biomarkers associated with HIE in neonates from southern Ethiopian public hospitals are not well understood.…”
Section: Introductionmentioning
confidence: 99%