Clinical characteristics and surgical outcomes of cardiac myxoma: A meta-analysis of worldwide experience

Oktaviono, Yudi Her; Saputra, Pandit Bagus Tri; Arnindita, Jannatin Nisa; Afgriyuspita, Lelyana Sih; Kurniawan, Roy Bagus; Pasahari, Diar; Milla, Clonia; Wungu, Citrawati Dyah Kencono; Susilo, Hendri; Multazam, Chaq El Chaq Zamzam; Alkaff, Firas Farisi

doi:10.1016/j.ejso.2023.107940

Cited by 8 publications

(3 citation statements)

References 128 publications

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“…Because of the reversibility of the left ventricle dysfunction after heart rate control, so we concluded to tachycardiomyopathy. According to the literature, surgical resection of myxomas is associated with an excellent outcome with low recurrence rate at 0.5 (95% CI = 0.0-1.1) per 1000 person-years, and also low mortality [9] The mainly post-operative complications are infection and bleeding, but tachycardiomyopathy has never been reported.…”

Section: Discussionmentioning

confidence: 99%

Atrial Tachycardia Revealing Obstructive Left Atrial Myxoma. Case Report

ZOUZOU

2024

clin. med. & helt. res. jour.

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Myxomas are the most common primary cardiac tumors; the most common localization is the left atrium, and may cause mitral flow obstruction so their clinical presentation could mimic severe mitral stenosis; trans thoracic echocardiography allows the diagnosis; we report a case of left atrial myxoma revealed by atrial tachycardia concomitant with dyspnea and signs of chronic right heart failure; despite surgical resection of the tumor, our patient had developed tachycardiomyopathy with severe left ventricular dysfunction, which recovered two months later, after intensive administration of antiarrhythmic treatment.

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Section: Discussionmentioning

confidence: 99%

Atrial Tachycardia Revealing Obstructive Left Atrial Myxoma. Case Report

ZOUZOU

2024

clin. med. & helt. res. jour.

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“…Notably, calcification and ossification can occasionally be observed in solid myxomas, although they are not typical features. Calcification is present in approximately 20% of cases, while ossification is observed in about 8%[ 2 , 6 ]. These occurrences, while relatively rare, pose diagnostic challenges on two-dimensional ultrasound due to the solid mass appearance and strong echogenicity accompanied by acoustic shadows.…”

Section: Discussionmentioning

confidence: 99%

“…CM that may cause serious complications, such as embolism, valve obstruction, and heart failure, have to be diagnosed and treated promptly. This is crucial for improving the prognosis and quality of life of patients [ 2 , 3 ]. CM have variable features in terms of location, shape, composition, and vascularization, which can make them difficult to distinguish from other lesions.…”

Section: Introductionmentioning

confidence: 99%

Two cases of atrial myxoma with calcification and ossification as the main features

Yin,

Deng,

Liu

et al. 2024

J Cardiothorac Surg

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Background Cardiac myxomas are the most common type of primary cardiac tumors in adults, but they can have variable features that make them difficult to diagnose. We report two cases of atrial myxoma with calcification or ossification, which are rare pathological subgroups of myxoma. Case presentation A 47-year-old woman and a 35-year-old man presented to our hospital with different symptoms. Both patients had a history of chronic diseases. Transthoracic and transesophageal echocardiography revealed a mass in the left or right atrium, respectively, with strong echogenicity and echogenic shadows. The masses were suspected to be malignant tumors with calcification or ossification. Contrast transthoracic echocardiography(cTEE) showed low blood supply within the lesions. The patients underwent surgical resection of the atrial mass, and the pathology confirmed myxoma with partial ossification or massive calcification. Conclusion We report two rare cases of atrial myxoma with calcification or ossification and analyze their ultrasonographic features. Transthoracic echocardiography and cTEE can provide valuable information for the diagnosis and management of such mass. However, distinguishing calcification and ossification in myxoma from calcification in malignant tumors is challenging. More studies are needed to understand the pathogenesis and imaging characteristics of these myxoma variants.

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