Clinical characteristics and thromboembolic risk of atrial fibrillation patients with and without congestive heart failure. Results from the CRATF study

Balsam, Paweł; Gawałko, Monika; Peller, Michał; Tymińska, Agata; Ozierański, Krzysztof; Zaleska, Martyna; Żukowska, Katarzyna; Szepietowska, Katarzyna; Maciejewski, Kacper; Grabowski, Marcin; Borkowski, Mariusz; Kołtowski, Łukasz; Praska-Oginska, Anna; Zaboyska, Inna; Opolski, Grzegorz; Bednarski, Janusz

doi:10.1097/md.0000000000013074

Cited by 13 publications

(8 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Left atrial (LA) dilation is also a predictor for the development of atrial fibrillation after cardiac surgery, and for the likelihood of an atrial fibrillation recurrence after a patient's initial presentation . Some studies also showed a positive association between atrial structure parameters and cardiovascular events . Cardiac ventricular structural values are important prognostic parameters for predicting patient outcome and represent an important component for the diagnosis of cardiac disease, risk stratification, and therapeutic decision‐making, and it is of high prognostic value in patients with ischemic and nonischemic cardiomyopathy .…”

mentioning

confidence: 99%

Age‐ and Sex‐Specific Reference Values for Atrial and Ventricular Structures in the Validated Normal Chinese Population: A Comprehensive Measurement by Cardiac MRI

Zhuang

et al. 2020

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Background Left and right cardiac structures have been shown to provide important prognostic information in patients with various cardiac disorders. They have always been important biomarkers in patients with heart failure and are crucial in the judgment of a variety of heart diseases. Purpose To provide age‐ and sex‐specific reference values of the normal cardiac structure of Chinese adults. Study Type Prospective study. Population In all, 200 healthy adult volunteers with 20 men and 20 women in each of five age deciles from 20 to 70 years. Field Strength 3.0T, steady‐state free precession (SSFP), turbo spin‐echo (TSE) sequence. Assessment The reference range of cardiac structure values was normalized to age, gender, and body surface area (BSA). The height, weight, blood pressure, and body mass index were measured as well. Statistic Tests Kolmogorov–Smirnov's, independent‐sample t‐tests, one‐way analysis of variance (ANOVA), Pearson's coefficient, and linear regression. Results The normalized left atrial (LA) transverse diameter (two‐chamber view) at end‐systolic, and left ventricular outflow tract diameter (LVOT) were significantly larger in females compared to males (all P < 0.001), while LA volume at end‐systole was found higher in males (males: 36.25 ± 10.03 mL vs. females: 32.78 ± 10.27 mL). With increasing age, there was a weak but significant decrease in normalized LA transverse diameter (two‐chamber view) at end‐ systolic (r = −0.25, P < 0.001). The normalized RA volume at end‐systole and RVOT diameter showed significant decrease with advancing age (r = −0.22, P = 0.002; r = −0.34, P < 0.001). The indexed left and right ventricular volumes were mostly smaller with advancing age. The LA longitudinal parameters correlated significantly with LA area measured in the two‐chamber view at end‐systole (r = 0.78, P < 0.001). Data Conclusion Reference values for the morphological parameters of the intracardiac structure by sex and age distribution are provided in a Chinese population. Level of Evidence 2 Technical Efficacy Stage 5 J. Magn. Reson. Imaging 2020;52:1031–1043.

show abstract

mentioning

confidence: 99%

Age‐ and Sex‐Specific Reference Values for Atrial and Ventricular Structures in the Validated Normal Chinese Population: A Comprehensive Measurement by Cardiac MRI

Zhuang

et al. 2020

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…A total of 5316 results were retrieved from the search (939 from PubMed and 4377 from EMBASE). After duplicates removal, and title and abstract screening, 130 full-texts were assessed for eligibility, and 46 studies were included for quantitative synthesis (Table 1 and Supplementary material online, Figure S1), with a total of 4 232 784 AF patients included: 3 studies were secondary analyses of randomized trials, 28,38,62 19 cohorts were based on administrative databases, 19,20,26,27,31,32,35,36,39,41,49,50,53,55,56,60,61,63,64 16 were observational multicentre studies, 21,22,24,25,33,34,37,40,42,[45][46][47][48]52,54,57 and 8 were observational single-centre studies 23,29,30,43,44,51,58,…”

Section: Resultsmentioning

confidence: 99%

Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients

et al. 2021

View full text Add to dashboard Cite

Funding Acknowledgements Type of funding sources: None. OnBehalf AF-COMET Collaborative Group Background Multimorbidity is a major concern in patients with atrial fibrillation (AF). Among other diseases, the prevalence of chronic obstructive pulmonary disease (COPD) in these patients is unclear, and its association with adverse outcomes is often overlooked. Moreover, uncertainties on the treatment of patients with both AF and COPD still exist, and may lead to undertreatment. Purpose The aim of this study is to estimate the prevalence of COPD, and its impact on management and outcomes in patients with AF. Methods A systematic review and meta-analysis was conducted according to PRISMA guidelines. All studies reporting the prevalence of COPD in AF patients were included and pooled. Data on comorbidities, beta-blockers (BBs) and oral anticoagulant (OAC) prescription, and outcomes (all-cause death, cardiovascular death, ischemic stroke, major bleeding) were pooled and compared according to COPD status; the impact of BBs on outcomes in patients with COPD was also investigated. All analyses were performed using random-effect models; subgroup analysis and meta-regressions were also performed to account for heterogeneity. Results Among 46 studies, the pooled prevalence of COPD was 13% (95% Confidence Intervals (CI): 10-16%), with high heterogeneity between studies; significant differences were found according to geographical locations and definition of COPD. A multivariable meta-regression model which included age, female sex, history of hypertension, diabetes and chronic heart failure (CHF) was able to explain a significant proportion of the heterogeneity (R2 = 69.8%). COPD was associated with a higher prevalence of diabetes, coronary artery disease, CHF and stroke (Fig. 1, panel A), as well as higher CHA2DS2-VASc scores and age (Fig. 1, panel B), and lower probability of BB prescription (Odds Ratio (OR): 0.77, 95%CI: 0.61-0.98). Patients with COPD showed higher risk of all-cause death (OR: 2.22, 95%CI: 1.93-2.55), cardiovascular death (OR: 1.84, 95%CI: 1.39-2.43) and major bleeding (OR: 1.45, 95%CI: 1.17-1.80) (Fig.1, Panel C); no significant differences in outcomes were observed according to BBs use in AF patients with COPD (Fig. 1, panel D). Conclusion COPD is common in AF, being found in 1 every 8 patients, and is associated with an increased burden of comorbidities, differential management and worse outcomes, with more than two-fold higher risk of all-cause death and increased risk of CV death and major bleeding. Therapy with BBs does not increase the risk of adverse outcomes in these patients. Abstract Figure.

show abstract

“…According to previous studies all over the world, both the prevalence and incidence of thromboembolism are high in patients with HCM, especially in patients with atrial fibrillation (AF) 12 , 13 , 15 , 22 , 23 . In Asia, based on the data on patients diagnosed with HCM from the entire Korean population between 2005 and 2015, the prevalence of stroke was approximately 10% 24 .…”

Section: Epidemiologymentioning

confidence: 99%

Thromboembolism in Patients with Hypertrophic Cardiomyopathy

Liu

Chen

et al. 2021

Int. J. Med. Sci.

View full text Add to dashboard Cite

Clinical characteristics and thromboembolic risk of atrial fibrillation patients with and without congestive heart failure. Results from the CRATF study

Cited by 13 publications

References 35 publications

Age‐ and Sex‐Specific Reference Values for Atrial and Ventricular Structures in the Validated Normal Chinese Population: A Comprehensive Measurement by Cardiac MRI

Age‐ and Sex‐Specific Reference Values for Atrial and Ventricular Structures in the Validated Normal Chinese Population: A Comprehensive Measurement by Cardiac MRI

Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients

Thromboembolism in Patients with Hypertrophic Cardiomyopathy

Contact Info

Product

Resources

About