Clinical Characteristics of 852 Patients with Subacute Thyroiditis before Treatment

Nishihara, Eijun; Ohye, Hidemi; Amino, Nobuyuki; Takata, Kazuna; Arishima, Takeshi; Kudo, Takumi; M, Ito; Kubota, Sumihisa; Fukata, Shuji; Miyauchi, Akira

doi:10.2169/internalmedicine.47.0740

Cited by 199 publications

(222 citation statements)

References 18 publications

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“…Nishihara et al previously examined the clinical characteristics of 852 untreated patients with SAT, and reported that 28.2% of the patients were febrile (body temperature ≧ 38°C in 19.2%), and that ≧ 60% had clinical symptoms and signs of thyrotoxicosis at the onset of the disease [12]. In our study, the mean body temperature was 37.0 ± 0.6°C (≧ 38°C in 19.2%), and symptoms of thyrotoxicosis were observed in 57.7% of the patients.…”

Section: Discussionmentioning

confidence: 99%

Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis

Arao

Okada

Torimoto

et al. 2015

J UOEH

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: The rate of recurrence of subacute thyroiditis (SAT) during prednisolone (PSL) therapy is approximately 10 to 20%. However, there is little or no information on the time period to relapse following administration of a tapered dose of PSL and the factors associated with such relapse. The aim of this study was to determine the correlation between SAT recurrence and PSL tapering regimen used in the treatment of SAT. This study was a medical record-based retrospective study and involved 26 patients (3 men, 23 women) who received PSL therapy for SAT. The primary endpoint was the association between recurrence and number of days required to taper daily PSL dose to 5 mg. The secondary endpoint was the relationship between recurrence and several variables including age, clinical score, free thyroxine, inf lammatory reaction, thyroglobulin, total treatment time, total dose of PSL and presence or absence of creeping thyroiditis. The SAT recurrence rate was 15.3%. There was no significant difference in the initial PSL dose between the non-recurrence and recurrence groups (27.5 mg vs 24.5 mg, P = 0.302). However, for the primary endpoint, significant differences were found between the two groups in time required for tapering PSL to 5 mg/day (non-recurrence: 44.3 ± 15.3 days, recurrence: 19.0 ± 11.9 days, P = 0.012). None of the clinical variables evaluated correlated significantly with SAT relapse. In conclusion, to prevent recurrence of SAT, consideration should be given to the period required for PSL tapering to 5 mg/day.

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Section: Discussionmentioning

confidence: 99%

Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis

Arao

Okada

Torimoto

et al. 2015

J UOEH

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“…On the other hand, SAT may similarly manifest with increased body temperature, a significant elevation of ESR and CRP but rather no leukocytosis, firm and painful goiter, with pain of typical radiation. However, SAT is usually accompanied by thyroid dysfunction (11). CAT can be diagnosed at any thyroid functional state, but typically it is not characterized by painful thyroid enlargement and biochemical or clinical signs of inflammation.…”

Section: Discussionmentioning

confidence: 99%

The role of sonoelastography in acute, subacute and chronic thyroiditis: a novel application of the method

Ruchała

Szczepanek‐Parulska²,

Zybek³

et al. 2012

European Journal of Endocrinology

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“…Disfunções de tireoide e paratireoide foram des critas na TA, sendo a elevação transitória de tiroxina, decorrente da liberação de estoques hormonais pelo processo de destruição folicular, algumas vezes acom panhada de sinais clínicos de tireotoxicose, a alteração mais frequentemente verificada (1,15).…”

Section: Discussionunclassified

Tireoidite supurativa aguda com múltiplas complicações

Fonseca

Avvad²,

Sanchez

et al. 2012

Arq Bras Endocrinol Metab

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SUMÁRIOA tireoidite supurativa aguda é uma desordem rara, mais frequentemente causada pelo Staphylococcus aureus ou Streptococcus pneumoniae, e atinge particularmente crianças com fístula do seio piriforme. Em adultos, a disseminação por via hematogênica a partir de foco infeccioso em orofaringe ou trato respiratório parece ser o principal mecanismo patogênico.Os sinais e sintomas iniciais da tireoidite aguda são semelhantes aos da faringite aguda e da tireoidite subaguda. Esse fato frequentemente retarda o diagnóstico dessa doença e aumenta o risco de complicações. Relatamos o caso de um paciente masculino de 28 anos, previamente saudável, que, após quadro de amigdalite, apresentou tireoidite aguda complicada por tireoto xicose, volumoso abscesso no lobo direito da tireoide, que se estendia à abertura superior do tórax com desvio da traqueia e compressão de grandes vasos, associado à trombose de veia jugular interna e sepse. Arq Bras Endocrinol Metab. 2012;56(6):388-92

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Clinical Characteristics of 852 Patients with Subacute Thyroiditis before Treatment

Abstract: Objective Subacute thyroiditis (SAT) is a transient inflammatory

Cited by 199 publications

References 18 publications

Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis

Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis

The role of sonoelastography in acute, subacute and chronic thyroiditis: a novel application of the method

Tireoidite supurativa aguda com múltiplas complicações

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