2012
DOI: 10.1016/j.schres.2012.03.024
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Clinical characteristics of heavy and non-heavy smokers with schizophrenia

Abstract: Up to 50–90% of persons with schizophrenia smoke cigarettes. Limited data and theories suggest persons with schizophrenia may smoke for different reasons than persons without schizophrenia, making smoking cessation interventions particularly challenging in this population. Although health consequences of smoking are widely known, less information is available regarding characteristics of different amounts of smoking exposure in this population. This study was performed to investigate differences between heavy … Show more

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Cited by 24 publications
(18 citation statements)
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“…Among those subjects, women were more likely than men to smoke their first cigarette within 5 min of wakening. In turn, we did not find an association between psychiatric disorders and CPD 20+, although there is evidence in the literature indicating this relationship [43][44][45]. Non-replication of the association could have been caused by several different factors.…”
Section: Discussioncontrasting
confidence: 84%
“…Among those subjects, women were more likely than men to smoke their first cigarette within 5 min of wakening. In turn, we did not find an association between psychiatric disorders and CPD 20+, although there is evidence in the literature indicating this relationship [43][44][45]. Non-replication of the association could have been caused by several different factors.…”
Section: Discussioncontrasting
confidence: 84%
“…Nicotine dependence is also found to be associated with symptom severity and poor outcome in patients with schizophrenia (Krishnadas et al, 2012). Furthermore, heavy smoking in these individuals makes them highly susceptible to develop various disorders such as cardiovascular diseases, lung cancer, and pulmonary conditions, resulting in premature mortality (Hennekens, 2007; Kelley et al, 2011; Shanmugam et al, 2007; Wehring et al, 2012). Therefore, a fundamental understanding of the neurobiological mechanisms that contribute to comorbid nicotine use in schizophrenia is essential to develop therapeutic strategies to improve smoking cessation, treatment outcome and life span of patients suffering from schizophrenia.…”
Section: Introductionmentioning
confidence: 99%
“…U prilog spomenutom svjedoče rezultati zanimljivog istraživanja koje su Wehrig i sur. 34 nedavno proveli na većem uzorku kroničnih pacijenata sa shizofrenijom oba spola (N = 745) u američkoj populaciji pacijenata. Iako nije pronađena značajna razlika u vrijednostima glukoze, tjelesne mase, BMI-ja i krvnog tlaka između lakih i teških pušača, uočeno je da su teški pušači imali statistički značajno veće koncentracije ukupnog kolesterola u plazmi.…”
Section: Rezultatiunclassified