Clinical Characteristics of Impacted Bile Duct Stone in the Elderly.

Arima, Nobuyuki; Uchiya, T; Hishikawa, Ruo; Saito, Masaki; Matsuo, Tetsuya; Kurisu, Shigeru; Umeki, Masahiko; Kita, Yuko; Koyama, Teruhisa; Hatta, Tomoko

doi:10.3143/geriatrics.30.964

Cited by 8 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been reported that the mortality rate of acute cholangitis was higher than 50 % before 1980, 10-30 % in 1981-1990s, and 2.7-10 % after 2000 [42,45,[79][80][81][82][83][84][85][86][87][88][89][90][91][92][93][94][95][96][97]. Such differences in mortality rate are assumed to have arisen from differences in severity and diagnostic criteria for the accumulated cases.…”

Section: Other Etiologies Of Acute Cholangitismentioning

confidence: 99%

TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis

Kimura

Takada

Strasberg

et al. 2013

J Hepato Biliary Pancreat

197

120

View full text Add to dashboard Cite

While referring to the evidence adopted in the Tokyo Guidelines 2007 (TG07) as well as subsequently obtained evidence, further discussion took place on terminology, etiology, and epidemiological data. In particular, new findings have accumulated on the occurrence of symptoms in patients with gallstones, frequency of severe cholecystitis and cholangitis, onset of cholecystitis and cholangitis after endoscopic retrograde cholangiopancreatography and medications, mortality rate, and recurrence rate. The primary etiology of acute cholangitis/ cholecystitis is the presence of stones. Next to stones, the most significant etiology of acute cholangitis is benign/ malignant stenosis of the biliary tract. On the other hand, there is another type of acute cholecystitis, acute acalculous cholecystitis, in which stones are not involved as causative factors. Risk factors for acute acalculous cholecystitis include surgery, trauma, burn, and parenteral nutrition. After 2000, the mortality rate of acute cholangitis has been about 10 %, while that of acute cholecystitis has generally been less than 1 %. After the publication of TG07, diagnostic criteria and severity assessment criteria were standardized, and the distribution of cases according to severity and comparison of clinical data among target populations have become more subjective. The concept of Electronic supplementary material The online version of this article

show abstract

Section: Other Etiologies Of Acute Cholangitismentioning

confidence: 99%

TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis

Kimura

Takada

Strasberg

et al. 2013

J Hepato Biliary Pancreat

197

120

View full text Add to dashboard Cite

show abstract

“…The reported mortality of acute cholangitis varies from 2.5% to 65% (Table 4). The mortality rate before 1980 was 50%,, and after 1980 it was 10%–30% . Such differences in mortality are probably attributable to differences in early diagnosis and improved supportive treatment.…”

Section: Acute Cholangitismentioning

confidence: 99%

“…The major cause of death in acute cholangitis is multiple organ failure with irreversible shock, and mortality rates have not significantly improved over the years . Causes of death in patients who survive the acute stage of cholangitis include multiple organ failure, heart failure, and pneumonia …”

Section: Acute Cholangitismentioning

confidence: 99%

“…The reported mortality of acute cholangitis varies from 2.5% to 65% [26][27][28][29][30][31][32][33][34][35][36][37] (Table 4). The mortality rate before 1980 was 50%, 26,27 and after 1980 it was 10%-30%.…”

Section: Prognosismentioning

confidence: 99%

“…The mortality rate before 1980 was 50%, 26,27 and after 1980 it was 10%-30%. [28][29][30][31][32][33][34][35][36][37] Such differences in mortality are probably attributable to differences in early diagnosis and improved supportive treatment.…”

Section: Prognosismentioning

confidence: 99%

See 2 more Smart Citations

Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines

Kimura

Takada

Kawarada

et al. 2007

J Hepatobiliary Pancreat Surg

399

288

View full text Add to dashboard Cite

This article discusses the definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis. Acute cholangitis and cholecystitis mostly originate from stones in the bile ducts and gallbladder. Acute cholecystitis also has other causes, such as ischemia; chemicals that enter biliary secretions; motility disorders associated with drugs; infections with microorganisms, protozoa, and parasites; collagen disease; and allergic reactions. Acute acalculous cholecystitis is associated with a recent operation, trauma, burns, multisystem organ failure, and parenteral nutrition. Factors associated with the onset of cholelithiasis include obesity, age, and drugs such as oral contraceptives. The reported mortality of less than 10% for acute cholecystitis gives an impression that it is not a fatal disease, except for the elderly and/or patients with acalculous disease. However, there are reports of high mortality for cholangitis, although the mortality differs greatly depending on the year of the report and the severity of the disease. Even reports published in and after the 1980s indicate high mortality, ranging from 10% to 30% in the patients, with multiorgan failure as a major cause of death. Because many of the reports on acute cholecystitis and cholangitis use different standards, comparisons are difficult. Variations in treatment and risk factors influencing the mortality rates indicate the necessity for standardized diagnostic, treatment, and severity assessment criteria.

show abstract

Pattern of bile cultures and antibiotic sensitivity tests in Sudanese patients diagnosed with obstructive jaundice: A single‐center prospective study

Babekir,

Abdelrahim,

Doush

et al. 2023

JGH Open

View full text Add to dashboard Cite

Background and Aim Biliary obstruction causes bacteriobilia and significant morbidity and high mortality, which necessitates prompt and effective treatment for a good clinical outcome. Hence, the aim of this study was to determine updated knowledge of biliary microbial spectrum, antibiotic sensitivity pattern, and key clinical factors of bacteriobilia. Methods This is a prospective study conducted during the period between November 2021 and December 2022 at Ibn Sina specialized hospital, Khartoum, Sudan, on 50 patients diagnosed with obstructive jaundice and symptomatic bacteriobilia who underwent open biliary surgeries electively. Bile samples were aspirated intra‐operatively and cultured, and antibiotic sensitivity tests were performed. Results Fifty‐four percent of patients diagnosed with obstructive jaundice who underwent elective open biliary surgeries were males with the ratio (2:1). Forty‐six percent of patients were between 61 and 75 years (elderly). The most frequent cause of obstructive jaundice was migrating biliary stones (48% of cases). Thirty‐two percent of patients were diabetic with bacteriobilia. The predominant isolated bacterial pathogen in this study was Escherichia coli (36% of cases). These biliary pathogens were sensitive to meropenem in 54% of cases and ciprofloxacin in 46%. Eventually, in all patients in this study, biliary bacterial pathogens were found to be resistant to a broad spectrum of antibiotics. Conclusion Careful selection of empirical antibiotic therapy based on surveillance of routine bile cultures during biliary tree procedures in patients with high risk of bacteriobilia will potentially help in improving the surgical outcomes and optimizing treatment of acute cholangitis, which is associated with high mortality.

show abstract

Clinical Characteristics of Impacted Bile Duct Stone in the Elderly.

Cited by 8 publications

References 0 publications

TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis

TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis

Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines

Pattern of bile cultures and antibiotic sensitivity tests in Sudanese patients diagnosed with obstructive jaundice: A single‐center prospective study

Contact Info

Product

Resources

About