Clinical characteristics of older patients: The experience of a geriatric short-stay unit dedicated to patients with COVID-19 in France

Godaert, Lidvine; Proye, Emeline; Demoustier-Tampère, David; Coulibaly, Pécory Souleymane; Hequet, Fanny; Dramé, Moustapha

doi:10.1016/j.jinf.2020.04.009

Cited by 70 publications

(72 citation statements)

References 9 publications

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“…The laboratory findings of 1194 patients were reported [10][11][12][13][14][15][16][17][18]24,[26][27][28]. The majority of the results were presented as median (IQR), except for Cheng B et al as mean and SD [13].…”

Section: Laboratory Findingsmentioning

confidence: 99%

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COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review

Neumann-Podczaska¹,

Al-Saad²,

Karbowski³

et al. 2020

Aging and disease

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The SARS-CoV-2 tendency to affect the older individuals more severely, raises the need for a concise summary isolating this age population. Analysis of clinical features in light of most recently published data allows for improved understanding, and better clinical judgement. A thorough search was performed to collect all articles published from 1st of January to 1st of June 2020, using the keywords COVID-19 and SARS-CoV-2 followed by the generic terms elderly, older adults or older individuals. The quality assessment of studies and findings was performed by an adaptation of the STROBE statement and CERQual approach. Excluding duplicates, a total of 1598 articles were screened, of which 20 studies were included in the final analysis, pertaining to 4965 older COVID-19 patients (≥60 years old). Variety in symptoms was observed, with fever, cough, dyspnea, fatigue, or sputum production being the most common. Prominent changes in laboratory findings consistently indicated lymphopenia and inflammation and in some cases organ damage. Radiological examination reveals ground glass opacities with occasional consolidations, bilaterally, with a possible peripheral tendency. An evident fraction of the elderly population (25.7%) developed renal injury or impairment as a complication. Roughly 71.4% of the older adults require supplementary oxygen, while invasive mechanical ventilation was required in almost a third of the reported hospitalized older individuals. In this review, death occurred in 20.0% of total patients with a recorded outcome (907/4531). Variability in confidence of findings is documented. Variety in symptom presentation is to be expected, and abnormalities in laboratory findings are present. Risk for mortality is evident, and attention to the need for supplementary oxygen and possible mechanical ventilation is advised. Further data is required isolating this age population. Presented literature may allow for the construction of better predictive models of COVID-19 in older populations.

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Section: Laboratory Findingsmentioning

confidence: 99%

“…Complications Despite only 9 studies reporting complications, the results pertained to 3241 patients [10,12,[15][16][17][18]24,26,29]. Renal impairment/injury was the most prominent complication with an incidence rate of 25.7%.…”

Section: Aging and Disease • Volume 11 Number 4 August 2020 999mentioning

confidence: 99%

COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review

Neumann-Podczaska¹,

Al-Saad²,

Karbowski³

et al. 2020

Aging and disease

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“…A fall was the first sign of the infection for more than a quarter of our patients. 32 Guan et al reported that thrombopenia and lymphopenia have been frequently observed in adult patients with COVID-19, but Godaert et al reported lymphopenia was more frequent than thrombopenia or leukopenia in their study. 32,33 Evaluating the molecular pathogenesis and the role of the immune system in modulating symptoms it can be assumed that susceptibility of COVID-19 to older adults is more.…”

Section: Symptoms Of Covid-19 and Its Effect On Geriatric Individualsmentioning

confidence: 73%

“…32 Guan et al reported that thrombopenia and lymphopenia have been frequently observed in adult patients with COVID-19, but Godaert et al reported lymphopenia was more frequent than thrombopenia or leukopenia in their study. 32,33 Evaluating the molecular pathogenesis and the role of the immune system in modulating symptoms it can be assumed that susceptibility of COVID-19 to older adults is more. There are various contributing factors for poor health outcomes and these include the physiologic changes of aging; multiple comorbid conditions such as heart and lung disease, diabetes, and dementia; and associated immunosuppressive disorders.…”

Section: Symptoms Of Covid-19 and Its Effect On Geriatric Individualsmentioning

confidence: 73%

“…Cough, delirium, dyspnoea, and asthenia were the other most commonly observed signs. 32 According to a study done by Guan et al in 1099 adults during the outbreak in China (median age 47 years), fever (88.7%), cough (67.8%), asthenia/fatigue (38.1%), sputum (33.7%) were most common symptoms. Diarrhoea was rare (3.8%).…”

Section: Symptoms Of Covid-19 and Its Effect On Geriatric Individualsmentioning

confidence: 99%

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Effect of COVID-19 in geriatric individuals and role of a prosthodontist in clinical setup in Indian populations: a literature review

et al. 2020

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Medical professionals including dentists are one of those high-risk professionals who can easily get affected by COVID-19 due to its highly contagious nature. Evaluating the molecular pathogenesis and the role of immune system in modulating symptoms it can be assumed that susceptibility of COVID-19 to older adults is more. This review aimed to summarize all the information available on electronic databases PubMed, PubMed central, Cochrane database related to the effect of COVID-19 ingeriatric individuals and guidelines for a prosthodontist during treatment of geriatric individuals in Indian population during this pandemic period. This review will focus on the characteristic symptoms and signs of COVID-19 ingeriatric individuals and how the prosthodontists during treatment of geriatric individuals in Indian populations can better equip themselves to prevent the spread of COVID-19 ina clinical setup.

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The Italian national survey on Coronavirus disease 2019 epidemic spread in nursing homes

Lombardo

Bacigalupo

Salvi³

et al. 2021

Int J Geriat Psychiatry

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Introduction Residents in facilities such as nursing homes (NHs) are particularly vulnerable to Coronavirus disease 2019 (COVID‐19). A national survey was carried out to collect information on the spreading and impact of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection in nursing homes, and on how suspected and/or confirmed cases were managed. We carried out a survey between 25 March 2020 and 5 May 2020. Materials and Methods All Italian nursing homes either public or providing services both privately and within the NHS were included in the study. An on‐line questionnaire was sent to 3292 nursing homes across all Italian regions. Nursing homes were also contacted by telephone to provide assistance in completing the questionnaire. Results A total of 1356 nursing homes voluntarily participated to the survey, hosting a total of 100,806 residents. Overall, 9154 residents died due to any cause from February 1 to the time when the questionnaire was completed (from March 25 to May 5). Of these, 7.4% had COVID‐19 and 33.8% had flu‐like symptoms, corresponding to a cumulative incidence of 0.7 and 3.1, respectively. Lack of personnel, difficulty in transferring patients to hospital or other facility, isolating residents with COVID‐19, number of beds and geographical area were the main factor positively associated to the presence of COVID‐19 in nursing homes. Discussion This survey showed the dissemination and impact of SARS‐CoV‐2 infection in Italian nursing homes and on how older and potentially chronically ill people residing in these long‐term care facilities were managed.

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Clinical characteristics of older patients: The experience of a geriatric short-stay unit dedicated to patients with COVID-19 in France

Cited by 70 publications

References 9 publications

COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review

COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review

Effect of COVID-19 in geriatric individuals and role of a prosthodontist in clinical setup in Indian populations: a literature review

The Italian national survey on Coronavirus disease 2019 epidemic spread in nursing homes

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