Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases

Kim, Min Jae; Kim, Na Young; Lee, Dong−Yun; Yoon, Byung-Koo; Choi, DooSeok

doi:10.1016/j.ajog.2011.02.044

Cited by 72 publications

(71 citation statements)

References 10 publications

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“…Mature teratomas are commonly detected incidentally during routine pelvic imaging studies. 8 Computed tomographic diagnosis of a benign cystic teratoma is more specific than sonography or radiography. Characteristic findings on CT include a fat-containing mass with Hounsfield units greater than normal fat because of the mixture of fat, hair, debris, and fluid.…”

Section: Discussionmentioning

confidence: 99%

“…4 Mature cystic teratomas often occur in younger patients, with an average age of 30 years. These teratomas are usually asymptomatic 8 and grow slowly, averaging 1.8 mm of growth per year. Mature cystic teratomas are typically evident within the pelvic bowl on radiographic examinations because of their fat and calcific density.…”

Section: Introductionmentioning

confidence: 99%

“…Mature cystic teratomas are typically evident within the pelvic bowl on radiographic examinations because of their fat and calcific density. Given that most of these tumors are asymptomatic, 5,8 they are often incidental findings on lumbar or pelvic radiography. 8 Treatment of mature cystic teratomas depends on the size, with nonsurgical management for smaller tumors, less than 6 cm, or cystectomy when larger.…”

Section: Introductionmentioning

confidence: 99%

“…Given that most of these tumors are asymptomatic, 5,8 they are often incidental findings on lumbar or pelvic radiography. 8 Treatment of mature cystic teratomas depends on the size, with nonsurgical management for smaller tumors, less than 6 cm, or cystectomy when larger. 5 Immature teratomas contain tissues derived from the 3 germ cell layers; but unlike mature teratomas, they demonstrate malignant behavior.…”

Section: Introductionmentioning

confidence: 99%

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A calcific pelvic mass in a woman with chronic spinal pain: a case of mature cystic teratoma

Kaeser

McDonald²,

Kettner

2011

Journal of Chiropractic Medicine

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Objective: The purpose of this case is to describe findings of a mature cystic teratoma and to further provide differential diagnoses for ovarian pelvic masses and calcifications. Clinical Features: A 27-year-old woman presented to a chiropractic teaching clinic with a chief complaint of chronic multilevel spinal pain. During a full spine radiographic examination, radiopaque densities were incidentally identified in the pelvic bowl visualized through a gonad shield. Follow-up pelvic radiography revealed several radiopacities of uniform density localized in the pelvic bowl. Intervention/Outcomes: Medical (gynecological) consultation led to ultrasonography of the pelvis that revealed a mature cystic teratoma. The patient underwent complete excision of the mass through a laparotomy procedure. The patient continued to receive chiropractic treatment of her original cervical and lumbar spine complaints, further suggesting that the pelvic mass was not a source of her musculoskeletal complaints. Conclusion: This case demonstrates the detection and proper referral of a patient with a calcific mass. The presence of a pelvic mass, suspected of arising from the ovary, requires additional diagnostic imaging and careful clinical correlation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A calcific pelvic mass in a woman with chronic spinal pain: a case of mature cystic teratoma

Kaeser

McDonald²,

Kettner

2011

Journal of Chiropractic Medicine

View full text Add to dashboard Cite

show abstract

“…Mature teratoma usually contains two or three germ cell layers from the endoderm, mesoderm and ectoderm (2). A typical mature teratoma often contains components from each of the three germ layers, including lipid, epithelium, bone, cartilage, hair, fat, muscle and nerve tissue.…”

Section: Introductionmentioning

confidence: 99%

Primary adrenal teratoma: Clinical characteristics and retroperitoneal laparoscopic resection in five adults

et al. 2015

Oncology Letters

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Abstract. Primary adrenal teratoma is extremely rare. To investigate the clinical characteristics and further enrich the limited knowledge on its diagnosis and treatment, the present study retrospectively analyzed the detailed clinical data of five patients with primary adrenal teratomas treated in the Peking Union Medical College Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China) between March 2009 and February 2014. The five patients were female, aged from 16 to 51 years (mean, 36.0±16.3 years), with solitary lesions that were incidentally found on routine physical examinations. The tumor size ranged from 2.4 to 9.0 cm (mean, 6.0±2.7 cm). Ultrasonography revealed a mixed echo in four patients, and computed tomography showed mixed density masses with fat components and calcification in three patients. Adrenal-related endocrine tests were normal in all five patients, and no abnormalities were found in the three patients who underwent somatostatin receptor scintigraphy examination. All patients were treated with retroperitoneal laparoscopic surgery, with no complications, and the resected tumors were identified as mature cystic teratomas pathologically. To date, the patients have been followed up for 4-60 months post-operatively, with no recurrence. In conclusion, this rare adrenal teratoma is an occult entity to which reproductive females are susceptible. The tumor exhibits no typical clinical manifestations or adrenal-related laboratory abnormalities, and the pre-operative diagnosis mainly relies on imaging characteristics of a heterogeneous lesion containing fat components with scattered and marginal calcifications. The preferred treatment is retroperitoneal laparoscopic surgery, and the prognosis is good.

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Imaging in gynecological disease (24): clinical and ultrasound characteristics of ovarian mature cystic teratomas

Heremans

Valentin

Sladkevicius

et al. 2022

Ultrasound in Obstet & Gyne

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Objective To describe the clinical and ultrasound features of ovarian mature cystic teratomas (MCTs). Methods This was a retrospective study. From the International Ovarian Tumor Analysis (IOTA) database, we identified patients with a histologically confirmed diagnosis of MCT who had undergone transvaginal ultrasound examination between 1999 and 2016 (IOTA phases 1, 2, 3 and 5) in one of five centers. Ultrasound was performed by an experienced examiner who used the standardized IOTA examination technique and terminology. In addition to extracting data from the IOTA database, available two‐dimensional grayscale and color or power Doppler images were reviewed retrospectively to identify typical ultrasound features of MCT described previously and detect possible new features using pattern recognition. All images were reviewed by two independent examiners and further discussed with two ultrasound experts to reach consensus. Results Included in the study were 454 patients with histologically confirmed MCT. Median age was 33 (range, 8–90) years and 66 (14.5%) patients were postmenopausal. Most MCTs were described by the original ultrasound examiner as unilocular (262/454 (57.7%)) or multilocular (70/454 (15.4%)) cysts with mixed echogenicity of cystic fluid (368/454 (81.1%)), acoustic shadowing (328/454 (72.2%)) and no or little vascularization on color Doppler (color score 1, 240/454 (52.9%); color score 2, 123/454 (27.1%)). The median largest lesion diameter was 66 (range, 15–310) mm. A correct preoperative diagnosis of MCT was suggested by the original ultrasound examiner in 372/454 (81.9%) cases. On retrospective review of ultrasound images of 334 MCTs that had quality sufficient for assessment, ‘dots and/or lines’ and/or ‘echogenic white ball’ (typical features according to the literature) were present in 271/334 (81.1%) masses. We identified four new ultrasound features characteristic of MCT: ‘cotton wool tufts’, ‘mushroom cap sign’, ‘completely hyperechogenic lesion’ and ‘starry sky sign’. At least one classical or novel ultrasound feature was present in 315/334 (94.3%) MCTs. Twenty‐nine (8.7%) MCTs manifested vascularized solid tissue, of which seven exhibited no typical features. Conclusion We provide a comprehensive overview of conventional and newly described ultrasound features of MCTs. Only a small proportion of MCTs did not manifest any of the typical features. © 2022 International Society of Ultrasound in Obstetrics and Gynecology.

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Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases

Cited by 72 publications

References 10 publications

A calcific pelvic mass in a woman with chronic spinal pain: a case of mature cystic teratoma

A calcific pelvic mass in a woman with chronic spinal pain: a case of mature cystic teratoma

Primary adrenal teratoma: Clinical characteristics and retroperitoneal laparoscopic resection in five adults

Imaging in gynecological disease (24): clinical and ultrasound characteristics of ovarian mature cystic teratomas

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