Clinical characteristics of patients with atrial fibrillation at a tertiary care hospital in the central region of Saudi Arabia

Salih, Salih A. Bin; Showlag, Mohammed S; Alqahtani, Mohammed A.; Taha, Ahmad; Yousuf, Muhammad; Abdullah, Mohammed

doi:10.4103/2230-8229.83374

Cited by 13 publications

(20 citation statements)

References 20 publications

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“…In the study by Salih A et al [9], it is determined that 71% of the patients with AF have LV dilatation, 27% have LV function depletion and 26% have left ventricular hypertrophy.…”

Section: Discussionmentioning

confidence: 99%

Which one is the first choice for rapid ventricular rate atrial fibrillation in emergency department: Metoprolol or Diltiazem? A randomized clinical trial

Memiş¹,

Ak²,

Öztürk³

et al. 2018

Journal of Surgery and Medicine

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Aim: Atrial fibrillation (AF) is the most common cardiac arrhythmia managed by emergency physicians. Primary goals of treatment are hemodynamic stabilization, ventricular rate control, and prevention of embolic complications. The aim of this study is to compare the drug responses of the patients who presented to the ED with AF with rapid ventricular response (AFRVR), their need for the second dosage and echocardiographic parameters. Methods: This is a prospective, single blind, randomized study. AFRVR patients were randomized and first group was given intravenous 0.25 mg/kg diltiazem as the calcium channel blocker; the second group was given intravenous 5 mg metoprolol. The vital findings and the clinical data of the patients in the 0, 2nd 5th, 15th and 30th minutes were recorded after each treatment. After the initial dosing, the patients having heart rate <110 beat/min in the 30th minutes were regarded as responders to the initial treatment. Nonresponders took second dosage of the same drug. After the rate control of all patients, a cardiologist performed the transthoracic echocardiography (TTE)'s of all participants. Results: Fifty of the patients were given diltiazem, 50 of them were given metoprolol. 45 of them (45%) had no first dose response; whereas 55 (55%) of them had. The rate of incidence for the first dose response in the patients having diltiazem was higher than the patients having metoprolol, which was statistically significant. There is statistically significant difference between rates of the valvular heart disease seen for the patients in responsive /unresponsive groups for both drugs. But diltiazem is more successful in presence of valvular disease than metoprolol. Conclusions: In this study, we found that diltiazem is more effective in the rate control of AFRVR in emergency department. This study showed that most of atrial fibrillation patients have valvular disease, and diltiazem is more effective than metoprolol in these patients. Ejection fraction, cardiac diameters are important in drug response.

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“…In the study by Salih A et al [9], it is determined that 71% of the patients with AF have LV dilatation, 27% have LV function depletion and 26% have left ventricular hypertrophy.…”

Section: Discussionmentioning

confidence: 99%

Which one is the first choice for rapid ventricular rate atrial fibrillation in emergency department: Metoprolol or Diltiazem? A randomized clinical trial

Memiş¹,

Ak²,

Öztürk³

et al. 2018

Journal of Surgery and Medicine

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“…The prevalence in the USA, Europe, and New Zealand was 2.3%, 2%, and 1.7%, respectively 2–4. In Saudi Arabia, only two hospital-based studies showed dissimilarities in the main causes of AF, whereas it has been attributed to the increasing aging population in the West 5,6. The implications of AF represent a great burden in terms of morbidity and mortality due to thromboembolic complications and heart failure (HF) as well as a wider healthcare and economic burden 1.…”

Section: Introductionmentioning

confidence: 99%

Atrial fibrillation: risk factors and comorbidities in a tertiary center in Jeddah, Saudi Arabia

Mashat¹,

Subki²,

Bakhaider³

et al. 2019

IJGM

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IntroductionAtrial fibrillation (AF) is the most common type of cardiac arrhythmia worldwide and carries significant risk of morbidity and mortality. The prevalence of AF is high in significant parts of the world, but not much is known from countries, such as Saudi Arabia.AimsTo study the risk factors, etiologies, comorbidities, and outcome of AF in Saudi Arabia.Patients and methodsA retrospective study was conducted in King Abdul-Aziz Hospital in Jeddah during the period 2010–2017. Data were collected from both the electronic-and paper-based medical records of patients with AF. The data included the demographic information, adverse lifestyle (smoking and obesity), cardiothoracic surgery, and comorbidities.ResultsA total of 167 patients were included in the analysis (43% were males). The mean age was 63.3±35 years and the mean body mass index was 28.8±83. Hypertension (HTN) was the most prevalent risk factor encountered (73.1%). This was followed by valvular heart disease, and type 2 diabetes mellitus (T2DM), which occurred in 58.7% and 53.3% of patients, respectively. Valvular heart disease was significantly associated with older age (P=0.002) and coronary artery disease (CAD) (P=0.001). Heart failure (HF) was associated with HTN (P=0.005), coronary heart disease (P=0.001), and chronic kidney disease (CKD) (P=0.003).ConclusionAF was more prevalent among females in Saudi Arabia. HTN, valvular heart disease, and T2DM were the most prevalent risk factors of AF in Saudi Arabia. Valvular heart disease was more prevalent among older patients and significantly associated with CAD. HTN, CAD, and CKD were the most significant risk factors for HF in patients with AF.

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“…Only few studies were published on the clinical characteristics, management, and cardiovascular risk factors in Saudi patients with AF. [ 14 15 ]…”

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confidence: 99%

Assessment and comparison of CHADS2, CHA2DS2-VASc, and HAS-BLED scores in patients with atrial fibrillation in Saudi Arabia

et al. 2016

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AIMS:No previous reports on the utilization of CHADS2, CHA2DS2-VASc, and HAS-BLED scores in atrial fibrillation (AF) patients in Saudi Arabia have been identified in the literature. The main objectives of this study were to assess and compare the distribution of CHADS2, CHA2DS2-VASc, and HAS-BLED scores and to identify the most common risk factors for stroke and bleeding among AF patients attending clinical pharmacists managed anticoagulation clinic.SETTINGS AND DESIGN:This cross-sectional study was conducted over 2 months period at clinical pharmacists managed anticoagulation clinic.METHODS:CHADS2, CHA2DS2-VASc, and HAS-BLED scores were calculated and compared for all eligible patients.RESULTS:Two hundred and sixty-four patients with AF were included in the analysis. The number of patients at low risk for stroke was found to be 14 (5.3%) using CHADS2 and only 4 (1.5%) using CHA2DS2-VASc. On the other hand, 64 patients (24.2%) were found at moderate risk for stroke using CHADS2 compared with 17 patients (6.4%) using CHA2DS2-VASc. Most of the patients were found to be at high risk for stroke using either the CHADS2 (70.5%) and CHA2DS2-VASc (92%). The study also revealed that most of the patients were at moderate (63.3%) to high (27.7%) risk of bleeding.CONCLUSIONS:The results of this study show that the percentage of patients at high risk for stroke and bleeding is very high. The study revealed that this could be attributed to the high prevalence of modifiable risk factors for stroke and for bleeding in Saudi patients with AF.

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Clinical characteristics of patients with atrial fibrillation at a tertiary care hospital in the central region of Saudi Arabia

Cited by 13 publications

References 20 publications

Which one is the first choice for rapid ventricular rate atrial fibrillation in emergency department: Metoprolol or Diltiazem? A randomized clinical trial

Which one is the first choice for rapid ventricular rate atrial fibrillation in emergency department: Metoprolol or Diltiazem? A randomized clinical trial

Atrial fibrillation: risk factors and comorbidities in a tertiary center in Jeddah, Saudi Arabia

Assessment and comparison of CHADS2, CHA2DS2-VASc, and HAS-BLED scores in patients with atrial fibrillation in Saudi Arabia

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